Biomedical subjects

B Schlechtweg

Publications and source records attributed to B Schlechtweg.

3 recordsLinked to original sources

PubMed1982

Conservative treatment of inoperable arterial occlusions of the lower extremities with intra-arterial prostaglandin E1.

Prostaglandin E1 has a strong vasodilator effect, it inhibits the aggregation of platelets and improves the microcirculation. The hormone is synthesized from arachidonic acid and 80-90 per cent is eliminated in the first transit of the pulmonary circulation. From 1 January 1978 to 30 June 1981 100 patients suffering from inoperable occlusion of the arteries of the lower limbs and facing amputation were treated with intra-arterial PGE1 by prolonged perfusion over an average period of 34 days. PGE1 0.1-0.2 ng kg-1 body weight min-1 was administered. Forty-seven of 100 legs were saved; 22 of 29 patients suffering from diabetes requiring insulin had to undergo amputation, but only 1 of 18 patients suffering from thromboangiitis obliterans had to have an amputation. The results of treatment in the 52 cases of uncomplicated arteriosclerosis lie in between, with 18 amputations. The complications that followed treatment were haemorrhage, arterial thrombosis, infection and mycotic aneurysms.

Adult↗

PubMedDate not supplied

Shoulder girdle compression syndrome.

Nowadays all compression syndromes at the upper chest like the costoclavicular syndrome, the scalenus syndrome, the hyperabduction syndrome and the Page-von Schroetter syndrome are included under the term of thoracic-outlet-syndrome. Apart from a constitutional disposition (cervical rib, anomalies of the tendons, etc.), it needs special factors like professional activities, sports, trauma, etc. to develop a T.O.S. syndrome. The symptoms range from prickling paresthesia, early fatigue, pains in shoulder and neck, claudication like pains and strong tendency towards swelling and rest pain or peripheral gangrene. Among 3126 vascular-surgical operations 128 transaxillary rib resections were performed during the time from June 1st, 1975 until March 31st, 1980. On 105 occasions rib resection was combined with the thoracic sympathectomy. In only 4 cases the resection of a cervical rib was sufficient to obtain decompression; in 15 cases the first rib had to be resected with a cervical rib. In 3 cases direct reconstructions of the artery and subclavian vein was performed by way of transaxillary approach. Postoperatively, 56% of the patients remained completely asymptomatic, 32% were decidedly improved and 12% unchanged.

Adult↗

PubMedDate not supplied

Arterial reconstruction for distal disease of the lower extremities by the in situ vein graft technique.

From January 1st, 1975 to December 31st, 1979, 285 femoropopliteal and femorocrural bypasses have been performed in 260 patients. In 57% of all cases the operation was carried out for limb salvage. The first 100 in situ transplants were angiographically examined 2 years after the operation. 5 years after the operation all patients were examined clinically, angiologically and by ultra sound Doppler technique. The patency rate amounts to 84% after 2 years and 76% after 5 years. With a patency rate of 57% after 2 years and 38% after 5 years the results achieved in the revascularization of a single crural artery are much more unfavourable. The results may be compared with those demonstrated by other authors who use the in situ technique. Compared to the classical venous bypass, the in situ bypass comes off a little better after a five years period.

Aged↗