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B Schockenhoff

Publications and source records attributed to B Schockenhoff.

30 records · Page 2Linked to original sources

[Etomidate for long term administration (author's transl)].

Etomidate in a new more concentrated solution given in 50 ml NaCl 0.9% was administrated to two groups of patients for prolonged sleep over 48-60 hours. The first group of patients got withdrawal symptoms after several operations. The second group contain seven patients after multiple injury, who were given the continuous infusion for adaptation to the respirator. The following levels were recorded:Psyst/diast, Part, HR; paO2, paCO2. After the administration of etomidate heart rate and blood pressure became normal. We did not find any significant changes, neither in the first group under spontaneous breathing of room air nor in the second under controlled respiration with room air. Blood pressure, heart rate, paO2 and paCO2 remained normal during the long term medication of etomidate.

Adult↗

[Infusion-etomidate-anaesthesia. II. The influence of different serum levels (author's transl)].

The influence if etomidate-infusion-anaesthesia on different serum levels of GOT, GPT, Na+, K+, urea, creatinine and glucose in the postoperative period was examined. There was only a decrease in K+. Although the decrease was significant (p less than 0.05), the results remained normal. The infusion-etomidate-anaesthesia supplemented by fentanyl seems to be an alternative to other types of anaesthesia.

Adult↗

[Etomidate-infusion-anaesthesia. I. Haemodynamics and blood gases analyses in the early postoperative period (author's transl)].

The influence of etomidate-infusion anaesthesia on blood pressure, heart rate and blood gases in the early postoperative period has been investigated on 14 patients. An infusion model for etomidate is described. Blood pressure and heart rate remained unaltered. There was only a max. fall of pO2 for 7.7% and a max. rise in pCO2 for 5.4%. Metabolic parameters did not change.

Adult↗

[The influence on the cardiovascular system of etomidate infusion anaesthesia combined with fentanyl/nitrous oxide (author's transl)].

Blood pressure and heart rate after the application of etomidate, soluble in alcohol 70% (a ml approximately or equal to 125 mg) and supplemented by fentanyl under controlled respiration with N2O/O2 as an continuous infusion for anaesthesia has been investigated during surgery. After the administration of fentanyl/etomidate (Hypnomidate)/succinylcholine the patients were intubated. Then the infusion of etomidate began with 1.5-2 mg/min for ten minutes, whereafter the dose was reduced to 0.15-0.25 mg/min. The continuous infusion of etomidate was stopped about 20 minutes before the end of the operation. The influence on the cardiovascular system during the whole operation was very minimal. The anaesthesia could be handled without any problems. Therefore the application of etomidate as a continuous infusion in combination with fentanyl and nitrous oxide 66% seems to be an effective technique of intravenous anaesthesia.

Adult↗

[Short gynaecological general anaesthesia with pentazocin and etomidate combined with room air (author's transl)].

A new short general anaesthesia for minor gynaecological operations is presented, which is also suitable for out-patients. The patient receives 0.05 mg. Atropin and 10 mg. Diazapam i.m. 30 minutes prior to the operation. Pentazocin in a dosage of 0.75 mg/kg. body weight was injected intravenously. 1 minute later Etomidate in a dosage of 0.3 mg/kg. body weight was injected intravenously. 1/3 of the initial dose of Etomidate was given as necessary at an average of 5 minutes following the initial dose. Through-out the procedure the patients spontaneously breathe room air. As advantages of the method are listed the minimal disturbances of the heart and the circulatory system, the lack of respiratory depression, the lack of specific organ toxicity, the absence of measurable release of histamine, the unlimited frequent repetition possible, the lack of damage to the personnel by anaesthetic gases and the safety and simplicity of the anaesthesia.

Ambulatory Care↗

[Blood gases analyses during short anaesthesia with fentanyl and etomidate (author's transl)].

Etomidate 0,3 mg/kg body weight and fentanyl 0,1 mg were given intravenously to two groups of patients--different by age--whilst spontanously breathing room-air. The effects on arterial blood pressure, heart rate and blood gases (arterial) were measured. In neither group did arterial blood pressure and heart rate changed appreciably but a significant fall of pO2 was found. There was only a small influence on acid-base-metabolism.

Acid-Base Equilibrium↗

[Pentazocin/etomidate, an intravenous anaesthesia under spontaneous breathing of room air (author's transl)].

The influence of an i. v. anaesthesia with Pentazocin/Etomidate on heart rate, arterial pressure and bood gases under spontaneous breathing of room air has been investigated on 50 patients with surgical and urological diseases. Heart rate, arterial pressure, pH, HCO3- and pO2 remained unaltered. There was only a slight increase in the beginning of the anaesthesia after injection of Pentazocin in pCO2 and a decrease in oxygen saturation which both were slightly significant. The use of this anaesthesia for ambulatory care is discussed.

Adolescent↗

[Headache after spinal analgesia with reference to the type of analgesic agent used (author's transl)].

The incidence and localization of headache after spinal analgesia were studied by means of a questionnaire. The case material comprised 503 spinal analgesias carried out with a 4% hyperbaric and a 2% isobaric solution of mepivacaine respectively and with 0.5% isobaric solution of bupivacaine. The use of the 4% solution of mepivacaine was followed by an increased incidence of prolonged dull headache in the occipital region. The observations suggest that the occurrence of headache after spinal analgesia may also depend on the type of analgesic agent employed.

Adult↗

Intravenous short narcoses in geriatric patients, A comparative study of etomidate with various analgesics.

Because of their often complicated pathology, geriatric patients may present special problems to the anesthetist. Whereas the hazards of surgery have been diminished through specific pre- and posttreatment, the so-called short narcosis has failed as yet to fulfill the requirements of maximum safety for the patient. In our study, two potent analgesics, i.e. fentanyl or pentazocine are associated with the narcotic etomidate for short narcosis. The effects either combination has on cardiovascular or respiratory values during unassisted ventilation are studied. Both the fentanyl/etomidate combination and the pentazocine/etomidate combination are characterized by stable cardiovascular conditions. The unfavourable effect on spontaneous respiration is greater after fentanyl as compared with pentazocine. Combined anesthesia of pentazocine and etomidate remains safe an easy to perform when the patient breathes spontaneously. If fentanyl is used, assisted respiration with oxygen is required.

Age Factors↗

[Para-spinal analgesia in obstetrics].

The use of regional analgesia and anesthesia in obstetrics has been established since the end of the 19th century. According to an agreement between German societies of anesthesiologists and obstetricians, regional anesthesia may be performed by both anesthesiologists and obstetricians under certain preconditions. At the RWTH Aachen hospital, the responsibility for different anesthetic techniques is divided between anesthesiologists and obstetricians in order to reduce legal risks. Caudal anesthesia is done by obstetricians, whereas anesthesiologists perform lumbar epidural anesthesia. A retrospective study over three years has shown comparable results. Lumbar epidural catheters were preferred in primiparous women, while caudal anesthesia was used more often in multiparous women. One-minute Apgar values as well as postpartum fetal arterial blood gas analyses did not differ significantly in both groups. The failure rate of caudal anesthesia was higher than that of lumbar epidural anesthesia. Blood pressure falls exceeding 20 percent of baseline were only seen in the epidural group (incidence 0.9 to 1.5 percent). The incidence of fetal bradycardia and the overall complication rate were similar in both groups.

Analgesia, Epidural↗