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Biomedical subjects

B Seguy

Publications and source records attributed to B Seguy.

18 recordsLinked to original sources
PubMedDate not supplied

[Methods of natural and voluntary sex selection. Value for the prevention of sex-linked malformations and of certain recurrent abortions].

Voluntary selection of the sex of a foetus may have an undeniable value in the prevention of certain diseases of malformations which are sex-linked. An indirect statistical control of the efficiency of these methods was carried out on 100 sterile treated couples. These couples agreed to respect a certain number of parameters which constitute the methods of voluntary selection of the sex of the foetus. Under these conditons and taking care that we were dealing only with cases where the sperm cell count was normal, the results were positive in 77%. It is probable the the results would have been above 80% if the parameter of the low pH of the vagina had been used as well. Attention was then directed to the possibility of using these methods to prevent certain sex-linked congenital malformations on the one hand (a classical idea) and prevention of certain repeated abortions on the other hand (a less well accepted idea). Three characteristic case histories have been reported to support these hypotheses.

Abortion, Spontaneous↗
PubMedDate not supplied

[Voluntary choice of sex. The present state of our knowledge].

Whether we like it or not, the next demand that the modern couple will make after birth control will be voluntary selection of the sex of their babies. Furthermore, this selection does have an undoubted medical value in preventing certain sex-linked congenital or hereditary diseases. Many research workers have turned their attention to these problems over the past years, especially in the U.S.A., in England and in Germany. After a historical review of the progress that has taken place in this area a study has been undertaken into the actual state of research in the U.S.A. and in Germany, in which the country the Federal Government has created a special department for scientific research. Our present knowledge into the methods that are adopted to obtain a foetus of male of female sex up to the present is then briefly explained. The results obtained by the principle research workers have been summarised. These are between 80 and 90 per cent success. The steps that have marked these discoveries in this field that is ill understood by the majority of doctors and the French public are outlined.

Body Temperature↗
PubMedDate not supplied

[Possible immunologic factors in natural selection of the sexes].

The foetal graft is protected from immunological rejection by the trophoblastic barrier, antigenically neutral. A deficiency of this protective barrier puts the highly antigenic egg contents in direct contact with the maternal organism. The formation of maternal antibodies, and the rejection reaction of the egg graft due to it, probabally explains certain miscarriages. We think that the male fetus must, in these cases, be more antigenic with regard to the graft carrying maternal organism, than the female fetus. A study of 222 pregnancies, with repeated spontaneous miscarriages confirms the clear preponderance of girls, among the non-premature and well-formed children born, and the efficiency of H.C.G. in protecting threatened pregnancies with male fetus.

Abortion, Spontaneous↗