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Biomedical subjects

B Seignon

Publications and source records attributed to B Seignon.

15 recordsLinked to original sources

[Value of discography in disk punctures in bacterial spondylodiscitis].

26 discographic examinations were performed during puncture of 28 intervertebral disks for septic spondylitis. Discography assures the operator that the diagnostic needle is correctly inserted in the intervertebral disk, without destroying the causative microorganisms. But, in particular, this examination reveals the presence of lesions which often are not suspected within the vertebra or the adjacent soft tissue, and notably the presence of large and frequently occurring pyogenic abscesses. Because of this capacity, this test has a certain diagnostic value in case of recent spondylitis and with erosive disk disease. This simple and safe procedure, in our opinion, justifies its routine utilization at the same time as disk puncture is performed for bacteriological assessment of infectious spondylitis.

Bacterial Infections↗

[Bacterial spondylodiskitis. Diagnostic problems].

The authors carried out 193 needle aspiration of needle biopsies of the discs or vertebrae in 7 French Rheumatology Units to draw up the bacteriological diagnosis in infectious spondylodiscitis. The bacteria were identified in 62.7% of cases on average, the score of the most favourable series reaching 80%. No incident or accident was observed. These results, which are definitely better than direct surgical exposure, suggest the widespread adoption of this technique before any antibiotic therapy whenever spondylodiscitis is suspected. However, a prospective study with a uniform protocol seems necessary in order to draw up more precisely the value and limits of the method.

Bacterial Infections↗

[Discopathies after fractures and destructive vertebral lesions during rheumatismal pelvispondylitis].

In three cases of rheumatic spondylitis, fracture across the disc of an ankylosed spinal segment (C5-C6, D7-D8, and D12-L1 respectively) resulted in rapid development of a discopathy with destruction of the adjacent vertebral bodies. In one of these cases, surgical exposure of the focus permitted anatomical study of the lesion; the changes that had developed after the fracture were inflammatory in appearance, which at first suggested infection by non-specific micro-organisms, an assumption that was rapidly abandoned. This misleading histological appearance largely explains why these destructive discopathies in spondylitis have long been regarded as a consequence of the rheumatic process itself. A review is presented of the arguments which suggest that they have, in fact, a mechanical pathogenesis, often determined by a fracture. From this it may be concluded that the treatment of choice is temporary immobilization in moderate cases and surgery with transplantation in complicated or unstable cases.

Aged↗

[Femoral nerve paralysis complicating anticoagulant treatments. A propos of 3 cases].

The authors report 3 new cases of femoral nerve paralysis complicating anticoagulant treatment. The first sign was pain, the neurological signs occurred later and the patient usually recovered but recovery was sometimes incomplete. The pathogenesis is not clear : a muscle hematoma, ischemia of the nerve trunk, and intraneural hemorrhage are the commonest theories.

Aged↗

[Destructive lesions of the middle and lower part of the cervical spine during rheumatoid arthritis. Study of the neurological complications. A case with quadriplegia].

Lesions of the middle and lower part of the cervical spine during rheumatoid arthritis are less frequent than those of the cervico-occipital joint. They concern the discs on the one hand, the posterior inter-apophyseal joints, on the other hand. The authors report a case of rheumatic spondylodiscitis of C5-C6 with dislocation, complicated by quadriplegia, and review other published cases of rheumatoid lesions of the middle and lower cervical spine with neurological complications. The mechanisms of these lesions and their complications are then discussed.

Aged↗

[Needle puncture of the intervertebral disk foci in the bacteriological diagnosis of infectious spondylodiscitis. Technic and results].

Clinical, laboratory, and radiological data do not make possible a certain diagnosis of infectious spondylitis: errors are thus possible, even frequent, and are harmful to the patient. In order to ensure a certain diagnosis and to avoid exploratory surgery as far as possible, the authors propose systematic needle puncture of the inververtebral disk--a technique that is simple and inoffensive to carry out in all disks below T4, and that, in a series of 18 cases, gave a success rate of 2 out of 3 (11 positive results). The technique, the results and the factors essential for success are described and analysed.

Adolescent↗

[The lateral atlantoaxial joint involvement in the rheumatoid arthritis. Report of ten cases and review (author's transl)].

An analysis of ten recent observations of lateral arthritis of C1-C2 during the course of rheumatoïd arthritis. This lesion, which is not rare, has charactéristic symptoms: localized pain together with occipital (Arnold's) neuralgia and specific blocking of head rotation towards the afflicted side. Frontal per-oral radiography shows joint line lesions most often unilateral, and a displacement of C1 towards the non afflicted side with pseudoinclination of the odontoïd process towards the afflicted side. Sometime more destructive lesions of the lateral masses of the atlas give them a triangular form and this may result eventually in an upwards "vertical" displacement of the odontoïd. The pain usually subsides in a few weeks after a conservative treatment with or without temporary immobilisation by a light removable cervical collar but the loss of the homolateral rotation of the head persists. Besides occipital (Arnold's) neuralgia, there seems to be no other neurologic complications; if they follow, it is due to an associated anteroposterior displacement.

Adult↗