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B Sellers

Publications and source records attributed to B Sellers.

10 recordsLinked to original sources

Decreased mortality from necrotizing pancreatitis.

BACKGROUND: Necrotizing pancreatitis has been associated with mortality rates of 25% to 80%. We reviewed our experience to determine whether aggressive debridement and comprehensive critical care improves survival. METHODS: The records of 989 patients with the diagnosis of pancreatitis admitted between January 1990 and September 1997 were retrospectively reviewed. Twenty-six patients required surgery for necrotizing pancreatitis and are the subjects of this review. RESULTS: Five of twenty-six patients (19%) died. For all patients, mean Ranson's score was 4.3 of 11, mean admission APACHE II score was 17.2, and mean Multiple Organ Dysfunction (MOD) score was 9.1. Poor outcome was associated with infected pancreatic necrosis (P = 0.03), elevated APACHE II score on admission (P = 0.04), and progression of MOD during the week after admission (P = 0.02). CONCLUSIONS: This review demonstrates improved survival in seriously ill patients with necrotizing pancreatitis as a result of comprehensive surgical and critical care.

Adult↗

Glomerulocystic kidney: proposed etiology and pathogenesis.

Glomerulocystic kidney, an unusual lesion seen only in infancy or early childhood, involves cystic dilatation of Bowman's space without evidence of urinary obstruction. This disease may result from intrarenal medullary obstruction in the third trimester of pregnancy because 1) it is similar to the cystic kidney lesion produced by urethral obstruction, 2) patients with glomerulocystic kidney have no evidence of extrarenal urinary tract obstruction and 3) most patients with glomerulocystic kidney have evidence of inflammation and fibrosis in the renal medulla. A prenatal drug history of prolonged maternal ingestion of phenacetin in an infant with glomerulocystic kidney prompted us to submit a possible etiologic source for the hypothesis of intrarenal obstruction.

Female↗

Glomerulocystic kidney. A hypothesis of origin and pathogenesis.

Glomerulocystic kidney, a disease primarily of infants, is characterized by dilation of Bowman's space. We describe an infant whose mother had regularly taken phenacetin during the latter half of her pregnancy. This history, with the renal morphologic features of our patient and those described in the literature, suggests that medullary obstruction contributes to the pathogenesis of this lesion.

Female↗