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Biomedical subjects

B Sivertsen

Publications and source records attributed to B Sivertsen.

8 recordsLinked to original sources
PubMed1989

Selegiline and levodopa in early or moderately advanced Parkinson's disease: a double-blind controlled short- and long-term study.

Selegiline 10 mg per day was compared to placebo as an adjunct to levodopa treatment in this double-blind study of early or moderately advanced Parkinson's disease. Thirty-eight patients completed an initial cross-over trial comprising two treatment periods, each of eight weeks, with a four weeks' wash-out period between them. Thirty of the patients continued in a long-term, double-blind parallel trial with a mean duration of 16 months (range 6-30 months). Selegiline treatment allowed a significant reduction of the necessary daily levodopa dose in both parts of the study and of the daily dosing frequency in the long-term investigation. In spite of this reduction of levodopa dose, an improvement was noted in tremor during the short-term selegiline periods. The side-effects were slight and related to dopamine effects and disappeared after reduction of levodopa-dose. The results support the use of selegiline as an early adjunctive treatment in Parkinson's disease.

Aged↗
PubMed1988

[Encephalitis].

Explore the source record for details and available documents.

Encephalitis↗
PubMed1977

Pain relieving effect of scalenotomy.

A follow-up was made of 37 patients treated by section of the anterior scalenus muscle. They complained of pain and/or paraesthesia in the upper extremities and tenderness over the muscle. All experienced relief of pain after injection of a local anaesthetic into the anterior scalenus muscle. Twenty-five patients were markedly improved. Patients with neurological signs seem to have a better result than those without (P = 0.06).

Adult↗