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Biomedical subjects

B Smeets

Publications and source records attributed to B Smeets.

9 recordsLinked to original sources
PubMed1997

Nd:YAG laser posterior hyaloidotomy for the treatment of a premacular vitreous floater.

A 63-year old man, with a large central vitreous floater, underwent a Nd:YAG laser posterior hyaloidotomy. Although the vitreous floater disappeared from the central optical axis, visual acuity did not improve. Microperimetry performed with the SLO revealed an absolute scotoma, which corresponded well in shape and dimension with the original vitreous floater. This finding suggests that a fragment of the neurosensory retina became detached together with the internal limiting membrane in the process of the vitreous collapse.

Aluminum Silicates↗
PubMed1996

[Use of the computer in dentistry: video superimposition and facial reproduction using the expedience of the computer interface].

Both video superimposition and computer facial reproduction play a useful role in the process of identification, particularly in the early stages of an investigation or when other more definitive methods may not be available. Video superimposition combined with a computer overlay technique can be used to establish whether a skull outline matches an image of a missing person, being a photograph, slide or videoimage. A computer driven robot can be used to simplify the alignment of the skull with the position of the head on the image. Craniofacial or facial reproduction are used in both 2D or 3D to produce an image which can be used for identification purposes.

Computer Graphics↗
PubMed1994

Learning phacoemulsification: the surgeon-in-training.

With the increasing trend towards phacoemulsification a perceived increased complication rate during the learning curve gives rise to a dilemma as to the best stage at which a surgeon-in-training can safely learn the technique. We prospectively analysed the complications and visual outcome of the first 160 phacoemulsification procedures performed by three surgeons-in-training. The main outcome measures included posterior capsule tear, vitreous and nuclear loss, surgical re-intervention rate and visual outcome. Posterior capsule tear occurred in 7 eyes (4.4%) and vitreous loss in 6 (3.8%). No nucleus was lost in the vitreous. Surgical re-intervention was required in 1 eye. Best corrected visual acuity was 6/12 or better in 88% of eyes. These results compare favourably with reports of surgeons-in-training learning extracapsular surgery and also with recently reported phacoemulsification series. This study indicates that with careful case selection and supervision phacoemulsification can be a safe procedure.

Aged↗
PubMed1993

Learning phaco in a teaching environment.

We prospectively analysed the complications and visual outcome of the first 160 phacoemulsification procedures performed by three surgeons in training under supervision. The main complications were posterior capsular tear (4,35%), vitreous loss (3,3%), nuclear loss (none) and surgical reintervention (one). Postoperative visual acuity was 0,7 or better in 94% of eyes without pre-existing pathology. Only one eye did not have a posterior chamber lens implanted.

Cataract Extraction↗
PubMed1991

ABO bloodgrouping on tooth material.

The ABO bloodgroup was determined on the pulp, dentin and enamel of 35 teeth using the adsorption-elution technique. A bloodstained compress from the extraction wound was used as the reference sample. Twenty teeth were examined within 6 weeks after extraction and fifteen teeth were examined 6-10 months after extraction. It was found, that bloodgrouping on pulp gives fairly good results, whereas the possibilities for correct bloodgrouping seem to be limited for dentin and debatable for enamel. Similar results were found in both groups of teeth.

ABO Blood-Group System↗
PubMed1989

Definition of subchromosomal intervals around the myotonic dystrophy gene region at 19q.

The localization to 19q of the gene causing myotonic dystrophy (DM) has been defined more precisely by refinement of the physical location of several linked markers. A somatic cell hybrid mapping panel from cells with t(1;19), t(12;19), and t(X;19) translocation products was constructed to define five different intervals across 19q. In addition, we have derived a series of cell hybrids by irradiation of a der(19)-only hybrid to further subdivide the cen-q13.1 region. Using an array of 36 cloned genes, anonymous DNAs, and enzyme markers, we have tested the location of the panel breakpoints and refined the regional assignment of several of these markers. All markers tightly linked to DM are localized mainly within 19q13.2, thus suggesting that the DM gene is also close to this region.

Animals↗
PubMed1988

Tight linkage between myotonic dystrophy and apolipoprotein E genes revealed with allele-specific oligonucleotides.

In 16 families with myotonic dystrophy (DM) a novel approach based on use of allele-specific oligonucleotides has been employed to study the linkage relationship between the apolipoprotein E (APOE) gene and DM. Synthetic oligonucleotides, designed to discriminate between APOE alleles epsilon 3 and epsilon 4, enabled us to distinguish heterozygous carriers in a hybridization assay. In a subset of families, the relevant segment of the APOE gene was enzymatically amplified to increase the sensitivity of the method. For DM and APOE, a maximum lod score (zmax of 7.47 was obtained at a recombination frequency (theta) of 0.047 (male theta = female theta). No recombination (maximum lod score of 5.61 at theta = 0.0) was found between APOE and the apolipoprotein CII (APOC2) gene. These results suggest that, in addition to APOC2, APOE is a useful marker for presymptomatic DM diagnosis.

Alleles↗