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Biomedical subjects

B Spano

Publications and source records attributed to B Spano.

17 recordsLinked to original sources

Incidence and duration of breast-feeding in a group of primiparae after physiological delivery.

A study has been performed on the incidence and duration of breast feeding in a group of 103 primiparous women who delivered in the Obstetrics Department of Sassari in 1980. The most important maternal variables that could be related with breast feeding were maternal age, level of school education, maternal feelings concerning the present pregnancy and maternal information concerning the advantages of breast feeding.

Adult↗

[An anthropometric study of Sassari population 3 to 36 months of age: females].

The average values (+ SD) for height and weight and head circumference of 666 females 3 and 36 months of ages from the city of Sassari (Sardinia) have been determined. Numerical values and smooth curves from the 3rd to the 97th percentile for height and weight and head-circumference have also been calculated. The results were compared with those published by E. De Toni et Al. 20 years ago. The data show a significant increase in height and weight among Sardinian children during the past 20 years. The availability of these new curves will permit a more correct evaluation of growth in Sardinian children.

Age Factors↗

[Trisomy 18: phenotypic and biochemical variability].

We report a case of Edward's syndrome showing some symptoms infrequently described in trisomy 18. The authors suggest that the phenotypic expression of symptoms rarely observed in the syndrome may be better interpreted as non specific consequence of the chromosomal imbalance, rather than directly related to genes on chromosome 18. A gene dosage effect for the enzyme Peptidase A, whose gene is mapped on chromosome 18, was also observed.

Aspartic Acid Endopeptidases↗

[An anthropometric study of the population of Sassari from 3 to 36 months old: males].

The average values (+/- SD) for height and weight and head circumference of 745 males 3 and 36 months of ages from the city of Sassari (Sardinia) have been determined. Numerical values and smooth curves from the 3rd to the 97th percentile for height and weight and head-circumference have also been calculated. The results were compared with those published by E. De Toni ed al. 20 years ago. The data show a significant increase in height and weight among sardinian children during the past 20 years. The availability of these new curves will permit a more correct evaluation of growth in Sardinian children.

Anthropometry↗

[The gene-dose effect for peptidase A on the erythrocytes of a patient with Edwards' syndrome].

The study of gene/dosage effect may be essential in tracing the pathogenetic steps which lead from an unbalanced chromosome anomaly to a pathological phenotype. We present a newborn with a clinical and pathological picture compatible with a diagnosis of Edwards' syndrome. Chromosome analysis on lymphocytes and fibroblasts confirmed the diagnosis showing the presence of trisomy 18. On chromosome 18 the enzyme peptidase A is mapped, and we demonstrated the gene/dosage effect for Pep A in the erythrocytes of our patient.

Abnormalities, Multiple↗

[Gene-dosage effect of esterase D enzyme on erythrocytes in a patient with Patau's syndrome].

The study of gene/dosage effect may be essential in tracing the pathogenetic steps which lead from an unbalanced chromosome anomaly to a pathological phenotype. We present a newborn with a clinical and pathological picture compatible with a diagnosis of Patau Syndrome. A chromosome analysis confirmed the diagnosis showing the presence of trisomy 13. On chromosome 13 the enzyme Esterase D (ESD) is mapped, and we demonstrated the gene/dosage effect for ESD in the erythrocytes of our patient.

Alleles↗

[Incidence and duration of breast feeding in the city of Sassari from 1976 to 1987].

The authors have studied the incidence and duration of breast feeding (BF) among children from Sassari born in the period 1976 to 1987 (3608 full-term, normal infants). The data have shown a progressive decrease in the incidence and duration of B.F. from 1976 to 1983 followed by a progressive increase in the last 4 years of the study. The authors point out the need for structured incentive program aimed at a better education of the mothers concerning the advantages of breast feeding.

Breast Feeding↗

[Anthropometric study of the Sassari population 6 to 11 years of age].

The average values [+/- SD) for height and weight of 1518 males and 1333 females between 6 and 11 years of age from the city of Sassari (Sardinia) have been determined. Numerical values and smooth curves from the 3rd to the 97th percentile for height and weight have also been calculated. The results were compared with those of the literature and particularly with those published by De Toni et Al. 20 years ago. The data show a significant increase in height and weight among Sardinian children during the past 20 years. The availability of these new curves will permit a more correct evaluation of growth in Sardinian children.

Body Height↗

[Height and weight increase in Sassarian children in the last 20 years].

Height and weight were obtained for 4349 children (2330 males and 2019 females), aged 3-11 years and attending the primary school in Sassari, Sardinian, in 1986. Findings were compared to those reported by De Toni and Aicardi for the same population in 1966 in order to find out possible changes occurred in this lapse of time. The results of our study show that in the last 20 years children have become taller and heavier, but at the same time they seem to be rather "fatter" than in the past.

Biometry↗

[An anthropometric study of a Sassari population 3 to 6 years of age].

The average values (+/- SD) for height and weight of 812 males and 686 females between 3 and 6 years of age from the city of Sassari (Sardinia) have been determined. Numerical values and smooth curves from the 3rd to the 97th percentile for height and weight have also been calculated. The results were compared with those of the literature and particularly with those published by De Toni et Al. 20 years ago. The data show a significant increase in height and weight among Sardinian children during the past 20 years. The availability of these new curves will permit a more correct evaluation of growth in Sardinian children.

Age Factors↗

[Clavicular fractures in the newborn infant].

The frequency of the fracture of clavicle in liveborn infants delivered in the Obstetric Department of the School of Medicine of Sassari was retrospectively evaluated for the years 1977, 1978 and 1979. Moreover, all the fractured live infants born in 1980 were prospectively identified and compared to a group of unmatched controls, which included the live infant born immediately before and that born immediately after the index case. The same procedure was adopted when the fracture was identified in two infants born consecutively. The following variables were studied: date and hour of delivery, sex, birthweight, gestational age, type of labour, presentation and mode of delivery, Apgar at one minute, parity of the mother. There were 108 cases and 194 controls. The frequency of the fracture of clavicle showed a linear increase from 2.2/100 live births in 1977 to 4.8/100 live births in 1980; males were slightly more affected than females and the right clavicle was more frequently fractured than the left one (67% for the four years altogether). In the prospective study the only statistically significant differences between cases and controls were found for birthweight (less than 0.001) and mode of delivery (P less than 0.025): cases weighed more and were more frequently born by instrumental delivery (vacuum or forceps) than controls; none of the fractured infants was born by caesarean section. One of the fractured infants was affected by osteogenesis imperfecta and two other presented a transitory paresis of the omolateral brachial plexus; in the remaining cases the prognosis was good.

Apgar Score↗

[The Silver-Russell syndrome].

The authors describe a case of Silver-Russell Syndrome with severe deficit growth. They display the major and minor features of the syndrome, and discuss about the possible pathogenetic causes.

Craniofacial Dysostosis↗