Biomedical subjects
Publications and source records attributed to B Stibr.
The title compound, 1,1,2,2-tetracarbonyl-1,2-&mgr;-carbonyl-4, 11-dimethylsulfido-closo-1,2-dicobaltadodecaborane, [Co(2)(C(4)H(20)B(10)S(2))(CO)(5)], has a closo 12-vertex 1, 2-Co(2)B(10)H(8) structure with SMe(2) ligands at the exo-4- and 11-positions. The cluster displays close structural similarities to the SEt(2) analogue.
Metalloboranes could serve perspectively as carriers of electrodense metals for electron microscopy, because they penetrate into tissues and are linked to them. The tested brominated cobaltacarborane anion, however, did not by far meet the demands of standard quality electronograms, as in combination with aldehyde fixation they give a low contrast of protein and nucleoprotein structures and contrary to osmium tetroxide they does not mark membrane lipids; it did not prove useful for contrasting of epoxide sections. The results, however, stimulate the seeking of more suitable boranes substituted with metals with a higher atomic number and a different molecular configuration.