Biomedical subjects
Publications and source records attributed to B Strittmatter.
This case report deals with an infected aortic aneurysm, caused by salmonella: a typical gastroenteritis with fever and diarrhoea led after a short remission period to septic reacerbation and rupture of infected aneurysm into the stomach. The patient died of an haemorrhagic shock. Nomenclature, pathogenesis and prognosis of infected aneurysms are discussed.
GH3 cells are shown to contain cytosolic progesterone receptor in a mean concentration of 270 fmol/mg protein with a dissociation constant (K(D)) for promegestone of 3 times 10(-9) M (4 degrees C). Estrogen receptor (K(D) = 1.8 times 10(-10) M) is demonstrated in cytosol (121 fmol/mg protein) as well as in 0.4 M KCl extracts (89 fmol/mg protein) of crude nuclear fractions. No progesterone receptor was detectable in the nuclear fraction. Both receptors are characterized by isoelectric focussing and by competition experiments. Addition of 10(-8) M estradiol to the growth medium increases progesterone receptor levels up to five, suggesting that the progesterone receptor is under estrogenic control.