PubMed Health⌕ Search

Biomedical subjects

B T Troost

Publications and source records attributed to B T Troost.

At least 73 records · Page 4Linked to original sources

Tuberous sclerosis and Klippel-Trenaunay-Weber syndromes. Association of two complete phakomatoses in a single individual.

Tuberous sclerosis and Klippel-Trenaunay-Weber (KTW) syndromes are phakomatoses which are believed to be inherited separately. A 41 year old woman presented with the classic features of tuberous sclerosis: adenoma sebaceum, mental retardation, and seizures. In addition, the diagnostic triad of KTW involved the left lower limb: cutaneous naevi, a vascular anomaly, and osteohypertrophy. Arteriography documented the presence of visceral tumours and an arteriovenous malformation of the leg. This is the first reported association of the fully-developed symptomatology of tuberous sclerosis and KTW in one person.

Adult↗

Macro square wave jerks.

Quantitative eye movement recordings in a patient with multiple sclerosis who had both macro square wave jerks and an internuclear ophthalmoparesis supported the concept of an internal brain-stem monitor that mediates corrective eye movements. A brain-stem model of this monitor illustrates the patient's motility disorder and the normal function of providing synergistic version and vergence corrections for dysmetric eye movements. Thus, the careful study of pathologic disturbances provides information relevant to the normal operation of the ocular motor system.

Adult↗

Comparative velocities of different types of fast eye movements in man.

The peak velocity-amplitude characteristics of voluntary saccades and the fast phases of caloric, rotational, and optokinetic (OKN) nystagmus were compared in ten human subjects in both light and, except for OKN, darkness. All these fast eye movements had similar velocities and all slowed in darkness. This study supports the presumption that the identical brainstem firing patterns found in monkeys for all fast eye movements also occur in man.

Adult↗

Optic neuritis due to acquired toxoplasmosis.

A pediatric patient with well documented acquired toxoplasmic optic neuritis is presented. Use of immunoglobulin M immunofluorescent antibody studies allow easier identification of recently acquired toxoplasmosis. Toxoplasmic optic neuritis and retinitis should be considered along with toxoplasmic meningitis or encephalitis as complications of acquired toxoplasmosis. Therapy is available which may decrease the duration of visual symptomatology and reduce residual visual impairment.

Adolescent↗

Abnormalities of gaze in cerebrovascular disease.

Disorders of ocular motility may occur after injury at several levels of the neuraxis. Unilateral supranuclear disorders of gaze tend to be transient; bilateral disorders more enduring. Nuclear disorders of gaze also tend to be enduring and are frequently present in association with long tract signs and cranial nerve palsies on opposite sides of the body. Nystagmus is a reliable sign of posterior fossa or peripheral eight nerve pathology. Familiarity with these concepts may help the clinician answer questions regarding localization and prognosis.

Cerebrovascular Disorders↗