Extra-corporeal circulation (E.C.C.) has been held responsible for histamine liberation incidents, essentially by a mechanical cause. In order to prove this, the authors assayed the overall histaminaemia at different times during E.C.C. in 11 patients. The results are discussed in terms of the patients' backgrounds, temperature, hematocrit, blood gases and the acid-base balance, and electrolyte balance. Histaminaemia, corrected depending on the dilution, did not show any significant variation, even in two patients who clinically had anaphylactic manifestations.

Acid-Base Equilibrium↗

PubMedDate not supplied

[Oculorespiratory reflex].

The lack of interest about oculorespiratory reflex (ORR) in surgery and experimental studies is obvious. However the authors insist on the importance of its clinical traduction. The purpose of this study is to determinate an experimental model with titration of stimulus (pressure or traction) and therapeutic test. Our first Results prove the clinic entity of O.R.R. In first conclusion, we can insist on the importance of ventilatory assistance during squint surgery and on the monitoring of PE CO2 and Sa O2.

Anesthetics, Local↗

PubMedDate not supplied

[A new anesthetic protocol in experimental ocular surgery in rabbits].

The authors describe a new anaesthetic protocol for laboratory rabbits. The surgery consists in an extracapsular lens extraction with intraocular lens implantation in the bag. The anaesthetic protocol requires: an intravenous induction with ketamine (20.2 mg/kg +/- 5) and midazolam (0.65 mg/kg +/- 0.3) and after an oral endotracheal intubation with a simple method, and at last maintaining halothane anaesthesia with a concentration between 3 and 4%. 45 anaesthesia were performed: the average time of the anaesthesia was 77 min +/- 16. No rabbit died because of this anaesthesia. The anaesthesia was a success for the surgeon who could operate in the best working conditions.

Anesthesia, Endotracheal↗