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Biomedical subjects

B Thorsen

Publications and source records attributed to B Thorsen.

7 recordsLinked to original sources
PubMed1993

[Who is responsible for EDP-based records? Experiences with introduction of EDP in a public health center].

In 1991, about 150 general practitioners in 37 health care units in the county of Oslo introduced computerized systems of case records which replaced the previous paper records. The hardware units were located outside the units, and were physically interconnected by a large computer network within the county of Oslo. By losing physical contact, the general practitioners also lost control of their patient records. The files could be looked into and manipulated with or without the doctors' knowledge. It was no longer clear who was responsible for the computerized case records. These experiences are discussed, paying attention to the Norwegian legislation and official regulations in the area. The conclusions are that a health care unit using EDP should have its hardware at the unit itself. The chief doctor of the unit should be responsible for the daily management of the EDP-unit, and for safeguarding the confidentiality of the patient records.

Ambulatory Care Facilities↗
PubMed1989

Zidovudine treatment of AIDS and ARC in Denmark 1987.

In 1987, a total of 138 Danish patients (94 AIDS and 44 ARC) received treatment with zidovudine, a total observation period of 572 treatment months. 15 AIDS and 1 ARC patient died after a median of 70 days (range 2-295). In the ARC group 4 patients developed AIDS (3 Pneumocystis carinii pneumonia, 1 Kaposi's sarcoma). Among the AIDS patients 38 new opportunistic infections were reported. 24 of these opportunistic infections occurred within 6 weeks after treatment initiation. 79 patients were observed for more than 3 months, 25 of these had their daily dose zidovudine reduced, usually from 1,200 mg to 600 mg, 9 others were temporarily off drug. HIV antigen was analyzed in serum samples from 93 patients. Of these, 28 (52%) of 54 initially HIV antigen-positive became antigen-negative, 7 (18%) of 39 initially HIV antigen-negative became antigen-positive within the first 8 weeks of zidovudine treatment. In 57 patients the total count of CD4+ cells were evaluated. A significant increase in the number of CD4+ cells was observed during treatment. In nearly all patients an increase in MCV and a decrease in neutrophil count was observed. 44 of the patients received a total of 307 blood transfusions on 94 occasions and 19 (14%) patients required multiple transfusions. The mortality among the AIDS patients was significantly lower compared to historical controls. In our experience zidovudine treatment is reasonably well tolerated and the side effects are manageable.

AIDS-Related Complex↗
PubMed1987

Duodenal diverticula demonstrated by endoscopic retrograde cholangio-pancreatography (ERCP)--their relationship to biliary calculi and gastrooesophageal reflux.

In 24 patients with duodenal diverticula, demonstrated by ERCP, food-stimulated gastrooesophageal reflux was demonstrated in 33% of the patients and biliary tract calculi in 81%. This is in contrast to a previous study in patients with duodenal diverticula demonstrated by barium examination where gastroesophageal reflux occurred in 81% and biliary tract calculi in 38% of the patients. Differences in clinical selection are believed to be the underlying cause to these varying results.

Adult↗
PubMed1976

Pseudomonas aeruginosa rash associated with a whirlpool.

A generalized pruritic pustular rash was reported by 32 of 61 (53%) persons who had used the swimming pool and whirlpool at a Minnesota motel in March 1975. A questionnaire survey indicated that attack rates were highest in periods of heaviest bather load. The rash appeared 8 to 48 hours after exposure and resolved within seven days. No rash was reported by 37 motel guests who did not use the pool. Pseudomonas aeruginosa, serogroup 11, was isolated from the skin lesions of two patients and from the water from both pools. Circumstantial evidence implicated the whirlpool as the most probable source of infection. Deficiencies in disinfecting equipment and technique were identified and corrected.

Adolescent↗