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Biomedical subjects

B Thull

Publications and source records attributed to B Thull.

7 recordsLinked to original sources

Performance evaluation of IVC systems.

An expert Working Group was set up in December 2000 to develop recommendations for users and industry on the evaluation of proper function and operation of individually ventilated cage (IVC) systems. The full report of their recommendations is in two parts--'Part 1: Test Instructions' and 'Part 2: Evaluation Criteria'--both of which have been published in full on the Laboratory Animals Ltd website. They can be found at http://www.lal.org.uk/IVC/index.html. Evaluation of and feedback on the recommendations to further refine their use and scientific basis is encouraged. This Summary Report provides a brief overview of the background to the development of the full report and the issues it addresses.

Animal Welfare↗

A case study in designing speech interaction with a patient monitor.

OBJECTIVE: New developments in speech interaction technology warrant the assumption that some of the interaction problems at anesthesia workplaces can be solved using speech interaction. One application might be the documentation of the anesthetic procedure. METHOD: To investigate this hypothesis, a speech input system was developed for a commercially available patient monitor (Datex-Ohmeda AS/3 Anesthesia Monitor with Record-Keeper), which in addition to standard functions also facilitates the generation of the anesthesia record. The speech input system was based on the IBM ViaVoice speech recognition technology (version Millennium Pro). The speech input device was preliminarily tested by 5 anesthetists wearing surgical masks under laboratory conditions and through retrospectively documenting 4 to 5 anesthetic procedures (each 12 to 17 documentation entries) in a calm situation. The speech interactive documentation procedure was compared with the conventional keyboard documentation procedure. RESULTS: The test persons achieved an overall word recognition rate between 72% and 92.4%. Between 76.5% and 97.7% of the single word commands could be completed without any corrections. The same qualifier held for 58.5% to 86.3% of the two- and three-word commands. Despite high speech recognition error rates, almost all documentation entries (236 of 238) could be finished using speech interaction. Comparing both documentation techniques, speech interaction was said to be more intuitive and caused less frustration than the keyboard documentation procedure. However, speech interactive documentation was rated less controllable because of the high speech recognition error rates and bccause the auditive feedback dialogues took too long. CONCLUSIONS: Modern speech recognition tools are still not advanced enough to facilitate the design of applications with an almost natural speech interface and widespread user acceptance. Nevertheless, many tasks in anesthesia have the necessary characteristics to be optimally supported by speech interaction. In contrast to earlier approaches to speech-interactive anesthesia workplaces, successful application today depends on the question of design rather than solely on that of technology. Many of the constraints and drawbacks of current technology can be overcome through appropriate design measures. The goals must focus first on identifying task areas in intensive care where speech-interaction can yield real benefit in terms of work efficiency, and second on developing and evaluating an ergonomic design of speech interaction. The intended users seem to look forward to the incorporation of speech interaction at the workplace.

Anesthesiology↗

Evaluation of two new ecological interface approaches for the anesthesia workplace.

OBJECTIVE: Currently, vital parameters are commonly displayed as trends along a timeline. However, clinical decisions are more often based upon concepts, such as the depth of anesthesia, that are derived by combining parameter relationships and additional context information. The current displays do not visualize such concepts and therefore do not optimally support the decision process. A new display should present an ecological interface (EI). The principle of EI design is to visualize all of the information necessary for decision making in one single display. METHODS: In the first approach, we developed an EI that visualizes 35 relevant parameters for anesthesia monitoring. All of the parameters are generated by an anesthesia software simulator. Sixteen anesthetists had to administer two simulated general anesthetics: in one setting working only with the simulator's monitors ("Sim Only"), and in another setting working with the simulator's monitors in combination with the EI ("Combi1"). During each experiment, one unexpected critical incident (either blood loss or a cuff leakage) had to be identified. The control and monitoring behavior was analyzed by recording the subjects' eye movements and think-aloud protocol. With the help of the eye-tracking results, we re-designed the EI. The new EI was then tested with no eye tracking ("Combi2") on eight anesthetists under analogous conditions as in "Combi1." RESULTS: Cuff leakage was identified significantly quicker in "Combi1" (7 of 8 cases; time (T): 65 s +/- 73 s) than in "SimOnly" (6 of 8 cases; T: 222 s +/- 187 s). Blood loss was identified in 5 of 8 cases (T: 215 s +/- 76 s) in "Combi1" as quickly as in "SimOnly" (all cases; T: 217 s +/- 72 s). In "Combi1," the EI was used as the main source of information (in 43 +/- 19% of time) and was frequently favored when identifying an evolving critical incident. In "Combi2," cuff leakage was identified in 7 of 8 cases (T: 70 s +/- 111 s) as quickly as in "Combi1." Blood loss was identified significantly quicker in all cases (T: 147 s +/- 62 s) in "Combi2" than in "Combi1" and in "SimOnly." CONCLUSION: The results have shown that appropriately designed EIs may improve the anesthetist's decision making and focus attention on specific problems. Now, the findings have to be tested in future studies by widening the scope using other simulated scenarios and being closer to reality under real conditions in the OR. Eye tracking proved to be a useful method to analyze the anesthetists' decision making and appropriately re-design interfaces.

Anesthesia, General↗

Ergonomic evaluation of an ecological interface and a profilogram display for hemodynamic monitoring.

OBJECTIVE: Comprehensive monitoring of the patient state and subsequent decision making is an essential part of the task of an anaesthetist. The physicians' decision making process is based upon a concept of partly abstract physiologic parameters such as depth of anaesthesia or contractility. This concept is derived from the measured parameters given on todays' trend displays in addition to context information available for the anaesthetist. We investigated two alternative approaches of display design for hemodynamic monitoring: 1) integrated displays based on ecological interface design, and 2) profilogram displays based on intelligent alarms. METHOD: To evaluate differences in decision making, the two displays and a trend display were compared in an experimental set-up with computer simulated vital parameter curves. From a start state with random parameter deviations from the ideal state, subjects had to achieve the ideal circulatory performance as fast as possible by manipulating vasomotor tone, heart rate, blood volume and contractility. To analyse subjects' decision making process, eye-tracking, event-logging, and the method of think aloud protocols were used. Twenty anaesthesiologists performed 113 experiments (approximately 2 with each display). RESULTS: The anaesthetists failed to achieve the task in 37% using the trend display, in 19% using the profilogram display, and in 13% using the ecological interface. Hence, a safer task solution was possible with the ecological interface and the profilogram display but at the expense of various performance parameters such as higher trial time, more interactions with the simulated system, and more frequent eye movements. In contrast to the trend display and the profilogram display, where anaesthetists were mainly focussed on controlling the left atrial pressure, such an behaviour was less observed with the ecological interface. CONCLUSION: Our results have shown that subjects came to more effective solutions with the traditional trend display. The main reason for this result may be their years of experience with this kind of display type. Regarding safe and goal-intended decision finding, the results are encouraging for further experiments with redesigned ecological displays. But these displays ought to have smoother changes with respect to the traditional trend displays. Furthermore, new experiments have to be performed under real or fairly real (e.g. together with an anaesthesia simulator) conditions to underline the positive results for ecological interfaces.

Adult↗

Design and validation of an intelligent patient monitoring and alarm system based on a fuzzy logic process model.

The process of patient care performed by an anaesthesiologist during high invasive surgery requires fundamental knowledge of the physiologic processes and a long standing experience in patient management to cope with the inter-individual variability of the patients. Biomedical engineering research improves the patient monitoring task by providing technical devices to measure a large number of a patient's vital parameters. These measurements improve the safety of the patient during the surgical procedure, because pathological states can be recognised earlier, but may also lead to an increased cognitive load of the physician. In order to reduce cognitive strain and to support intra-operative monitoring for the anaesthesiologist an intelligent patient monitoring and alarm system has been proposed and implemented which evaluates a patient's haemodynamic state on the basis of a current vital parameter constellation with a knowledge-based approach. In this paper general design aspects and evaluation of the intelligent patient monitoring and alarm system in the operating theatre are described. The validation of the inference engine of the intelligent patient monitoring and alarm system was performed in two steps. Firstly, the knowledge base was validated with real patient data which was acquired online in the operating theatre. Secondly, a research prototype of the whole system was implemented in the operating theatre. In the first step, the anaesthetists were asked to enter a state variable evaluation before a drug application or any other intervention on the patient into a recording system. These state variable evaluations were compared to those generated by the intelligent alarm system on the same vital parameter constellations. Altogether 641 state variable evaluations were entered by six different physicians. In total, the sensitivity of alarm recognition is 99.3%, the specificity is 66% and the predictability is 45%. The second step was performed using a research prototype of the system in anaesthesiological routine. The evaluation of 684 events yielded a sensitivity, specificity and predictability of the alarm recognition of more than 99%.

Anesthesiology↗

Approach to computer-based medication planning and coordination support in intensive care units.

Due to more and more complex diagnosis and therapy measures, the critical care of patients requires an extensive work organisation which comprises patient, doctors, nurses and external services (e.g., central laboratory). In this organisation, the documentation plays a major role for the planning and coordination of work procedures and information flow within the medical staff. Various studies in intensive care units (ICU) reveal that the complex work organisation and the related information flow are faulty. Breakdowns are often caused by a lack of coordination between doctors and nurses and by poor transparency of work procedures. A typical example is the incorrect application of a doctor's medication orders by a nurse because she might have overseen a plan modification. This intransparency increases the strain on the medical staff and might result in critical effects on the patient. One approach to design a computer support for medication planning as well as the coordination when executing medication plans is given by work flow models. This paper shows that work flow models could be used to improve deficiencies in medication planning and coordination. Furthermore, it is demonstrated how such a support can be mediated to the user through an appropriately designed user interface.

Communication↗