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B Tumiati

Publications and source records attributed to B Tumiati.

35 records · Page 2Linked to original sources
PubMedDate not supplied

Hypoparathyroidism secondary to Riedel's thyroiditis. A case report and a review of the literature.

Riedel's thyroiditis is a rare condition in which the thyroid gland is replaced by fibrous tissue. Fibrosis in various distant sites is a possible concomitant event. We report a case of Riedel's thyroiditis complicated by mediastinal fibrosis, a tumefactive fibro-inflammatory lesion of the neck and primary hypothyroidism. A review of the literature in which only 8 previous cases of hypoparathyroidism secondary to Riedel's thyroiditis have been recounted concludes the report.

Acute Disease↗
PubMedDate not supplied

Human parvovirus B19 infection mimicking systemic lupus erythematosus in an adult patient.

We report a case of widespread immune activation with moderate cytopenia during acute infection with human parvovirus B19 in an adult female patient, in whom five criteria for the diagnosis of systemic lupus erythematosus were present at disease onset. Our case is unusual due to the presence of a cutaneous rash mimicking leukocytoclastic vasculitis at presentation, moderate leukopenia with thrombocytopenia and the presence of a broad array of autoantibodies. Diagnosis was established on the grounds of serological tests confirming recent infection with human parvovirus B19; spontaneous regression of clinical and laboratory abnormalities was observed within 16 weeks, ruling out classic systemic lupus erythematosus. We conclude by proposing that human parvovirus B19 infection should be included in the differential diagnosis of lupus-like syndromes in adult patients.

Adult↗
PubMedDate not supplied

[High-dose immunoglobulins for the treatment of rheumatoid arthritis: pilot study of 7 cases].

High intravenous doses (400 mg/kg) of gammaglobulin (IVIG) were administered monthly for six months to 7 patients with severe rheumatoid arthritis (RA). In all cases, previous treatment with NSAIDs and corticosteroids and in 3 of them with gold and/or methotrexate had been ineffective. A 50 per cent improvement of Ritchie index was obtained in 6/7 patients, morning stiffness was reduced from greater than 2 hours to less than 30 minutes in 6/7 patients. Swollen joints and Lee index improved in all patients. ESR did not show any change but RCP improved in 6/7 patients. The study of lymphocyte subpopulation showed no substantial changes in CD20+, CD3+, CD4 and CD8 cells as well as in CD4/CD8 ratio and a significant increase in 2H4+T cells without changes in 4B4+ subpopulation. IVIG improved the clinical and laboratory features of patients with severe RA. The major problem raised by IVIG therapy is its high cost suggesting that this therapy should only be applied in well selected patients with RA.

Adult↗
PubMedDate not supplied

[Acute idiopathic thrombocytopenic purpura after anti-influenza vaccination].

A case of acute thrombocytopenic purpura, presented with sudden onset of petechiae and ecchymoses, as a possible complication of antinfluenza vaccination with inactivated viruses is reported. Within 15 days of vaccination the platelet count fell down, serum antiplatelet antibodies were detected in high titre and bone marrow aspiration revealed an increased number of megakaryocytes. Corticosteroid therapy was followed by a complete recovery within ten days; three months later, platelets number remained in the normal range.

Adult↗
PubMedDate not supplied

[Reye's syndrome in an adult following therapy with salicylates in Still's disease].

Reye's syndrome or encephalopathy with fatty infiltration of the liver occurs mainly in childhood and to a lesser degree in adult age. Salicylate may play a role in the pathogenesis of this syndrome. Still's disease is a form of juvenile rheumatoid arthritis very rare in the adult. A case is reported of a 39-year old woman who developed Reye's syndrome while on aspirin therapy for the treatment of a classical adult Still's disease.

Arthritis, Juvenile↗
PubMedDate not supplied

[Necrotizing lymphadenitis (Kikuchi's disease) and systemic lupus erythematosus: a single entity?].

Kikuchi's necrotizing lymphadenitis is a histologically alarming but self-limiting lesion typically affecting the cervical lymph nodes of young women. The authors report 2 cases of systemic lupus erythematosus with the finding of Kikuchi's disease on lymph node biopsy. Considering the common infectious and/or immunologic etiologies described in both disorders, coexistence of both conditions suggests the possibility that they share a common etiology.

Adult↗