[Blood serum viscosity and protein fractions in patients with advanced-stage vascular type of vibration disease].
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Biomedical subjects
Publications and source records attributed to B Turczyński.
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300 workers of metalurgical plant exposed to vibrations were divided according to the chief work tool into the three groups: 1) moulder, 2) mould cleaner and 3) ironworker--grinder. The velocity of vibration was measured and the spectrum of vibrations examined. The product of vibration velocity excesses was evaluated within the following three bands of frequency: 16--63 Hz, 125--250 Hz, 500--2000 Hz and the frequency of occurrence of the two main forms of vibration disease, i.e. angioneurosis and osteoarthrosis was calculated. The osteoarthretic form of vibration disease was significantly more frequent when the multiplicity of surpassing the velocity of vibration occurred with low frequencies (moulders), and angioneurotic form was more frequent at high and very high frequencies. It seems, that "the safe limit" of vibration frequency should be transferred to frequencies higher than 500 Hz.
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Male Wistar rats were treated intraperitoneally once per week for 12 weeks with following detergents: Olbrotol-18 (nonionic detergent), a product of etheric condensation of 18 moles of ethylene oxide to 1 mole of the mixture of olein alcohol and cetyl alkohol in ratio 1:1, in a dose of 10 mg/kg; SBO (anionic detergent), sodium 2-ethylhexylsulfosuccinate, in a dose of 10 mg/kg and Sterinol (cationic detergent), benzalkonium bromide, in a dose of 0.6 mg/kg. The control rats were injected with 0.9% saline solution. The content of total cholesterol, beta-lipoproteins and total lipids in serum were estimated. The increase of total cholesterol and the decrease of beta-lipoproteins content in serum of rats after all used detergents were observed as compared with the control. The increase of total lipid content only after long-term treatment with Olbrotol-18 was found. It is concluded that long term intraperitoneal treatment with detergents changes similarly the contents of total cholesterol and of beta-lipoproteins in blood serum of rats.
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Blood and plasma viscosity, total lipids, triglycerides, total cholesterol, free fatty acids, fibrinogen, lipid-gram, and hematocrit were determined in 53 patients with occlusive arteriosclerosis in the lower limbs prior to and after ozone therapy. At the same time the distance of the intermittent claudication was measured. A significant prolongation of the distance walked painlessly, reduction in blood and plasma viscosity as well as the decrease in total cholesterol after therapy with ozone correlated with a decrease of the blood viscosity.
Blood and plasma viscosity, total blood lipids, triglycerides, total cholesterol, free fatty acids, fibrinogen, hematocrit, and lipidogram were determined in patients with diabetes mellitus type II and coexisting symptoms of the obliterative arteriosclerosis of the lower limbs. Intermittent claudication distance has been measured parallel. The same tests have been carried out after ozone therapy. A significant improvement in the intermittent claudication and reduction in blood and plasma viscosity have been noted. There was statistically significant correlation between intermittent claudication decrease and blood viscosity reduction following ozone therapy.
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