Gm(a) grouping in neonates and children.
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Biomedical subjects
Publications and source records attributed to B Turowska.
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Tests were carried out on 89 specimens of human inner ear fluid and the results compared with those of blood and salivary gland tests. It was found that ABO(H) group substances are present in the perilymph of secretors.
The authors carried out investigations on the possibility of determining the Gm(1) factor in endolymph taken from human cadavers, as compared with tests of the blood. No difficulties or anomalies were found in the determination of Gm(1) factor either in the endolymph or the blood taken from cadavers.
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The distribution of red cell acid phosphatase types in 3244 unrelated Polish adults is reported. Gene frequencies Pa = 0.3594, Pb = 0.5643 and Pc = 0.0763 were obtained. In a forensic case of disputed paternity an apparent mother/child incompatibility respect to red cell acid phosphatase was found, the mother appearing as type B and the child as type A. Determination of acid phosphatase activity suggested the presence of a silent gene Po. The phosphatase levels were about half the values expected as determined in 237 adults representing the different phenotypes.
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Phosphoglucomutase (PGM1) subtypes in South Polish population were examined by thin-layer polyacrylamide gel isoelectrofocusing (pH 5-7) using fresh hemolysates from 460 unrelated adults. The allele frequencies in Polish population are as follows: PGM1+1 = 0.6402, PGM1-1 = 0.1185, PGM2+1 = 0.1880, PGM2-1 = 0.0533.
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The prevalence of the markers of blood groups ABO, MN, Kell, Hp, Gm1 was determined in 723 persons belonging to three age groups: from 61 to 91 years, and was compared with a similar study in a population of adults aged 20 to 60 years. It was found that with respect to MN markers the proportion of NN homozygotes was significantly increased, mainly in females aged 71-80 years. In the haptoglobin system a considerable increase was noted in the prevalence of Hp 1-1 phenotype and the appearance of ahaptoglobinaemia. Increased prevalence of the Gm1 marker was observed only in females aged 71-80 years. On the other hand, no significant differences were noted in the frequency of the phenotypes of the ABO and Kell blood groups. These preliminary results confirm the stability of the serological polymorphism in the ABO and Kell blood groups, and in the remaining blood groups studied a natural selection may be supposed to exist. Characteristic changes in the distribution of the frequency of the determined genetic markers encourage the continuation of such studies.