Biomedical subjects

B U Umeh

Publications and source records attributed to B U Umeh.

7 recordsLinked to original sources

PubMed1994

Pericarditis: a persisting surgical problem.

A study of pericarditis treated surgically over a period of 14.5 years was conducted to evaluate the current pattern and management of this disease in a tropical environment. The series comprised 86 patients (58 males and 28 females) aged from 5 months to 60 years (mean 21.1 years). Pericarditis was effusive in 41 patients, calcific in 33 and fibrous in 12. Aetiological or associated factors were non-specific, pyogenic infection, rheumatic heart disease, endomyocardial fibrosis, tuberculosis and amoebiasis in 36, 21, eight, eight, six and four patients, respectively. All the patients were in New York Heart Association (NYHA) functional class III or IV. Operative treatment involved pericardiotomy with tube drainage in 32 patients, pericardiectomy in 49, and pericardiotomy with subsequent pericardiectomy in five. The total hospital mortality rate was 8.0%, and was largely a result of severe pre-operative cardiac decompensation and multiple organ failure. Of the 79 early survivors, 91% reverted to NYHA functional class I or II. Surgical treatment remains the most effective management of chronic pericarditis which still constitutes a major clinical problem in some countries.

Adolescent↗

PubMed1989

Ventilatory pulmonary function study in healthy young Nigerian adults.

Ventilatory pulmonary function was studied in 108 healthy young Nigerian adults using an electronic spirometer, with a view to determining the normal values of function for healthy Nigerians. The measured values of forced vital capacity, forced expiratory volume in 1 sec, maximum voluntary ventilation, and peak flow rate were compared with those obtained from similar studies on Nigerians and the predicted values for Caucasians. Higher values of function were obtained in Nigerian males than in the females. Nigerian males, however, showed lower values when compared with Caucasians of similar anthropometric measurements; there was no difference between the females in this study and their Caucasian counterparts. There were also some similarities and differences between the values obtained in this study and those of similar studies in Nigerians of different socio-ethnic backgrounds. The results emphasize the necessity for a ventilatory normogram for each socio-economic or ethnic grouping of individuals.

Adult↗

PubMed1987

Management of traumatic rupture of the diaphragm.

Traumatic rupture of the diaphragm is a potentially serious injury which presents in different forms depending on the mechanism of the causative trauma. Over a 7 year period, 20 patients (17 male and 3 female) with traumatic rupture of the diaphragm were seen in our unit; their mean age was 25.6 years. Automobile accidents caused the diaphragmatic injuries in 65 per cent of cases while falls from trees were the cause of injury in 10 per cent. Ten patients (50 per cent) were seen within 7 days of the injury and 95 per cent within 3 months. The left hemidiaphragm was ruptured in 85 per cent and the right in 15 per cent of cases. Fifty ribs were fractured in fourteen patients (70 per cent) but there were no pelvic fractures. Fourteen patients (70 per cent) had gastrointestinal visceral herniation into the thorax, the stomach, omentum, colon and spleen being the commonest herniating organs. Successful surgical repair was achieved in 18 patients, 4 of whom also had splenectomy; 2 patients were treated conservatively. A high index of suspicion and early surgical treatment are the mainstay of successful management of traumatic rupture of the diaphragm with or without herniation of abdominal organs.

Accidents, Traffic↗

PubMed1986

Sacral acupuncture for pain relief in labour: initial clinical experience in Nigerian women.

Sacral acupuncture was used for pain relief during labour in 30 pregnant Nigerian women. It produced clinically adequate analgesia in 19 women (63.3%). 6 women in this group (31.6%) reported that they had experienced no pain whatsoever throughout the period of labour and delivery (average duration - 8 hours). 11 women (36.7%) had no pain relief and required pethidine injection when sacral acupuncture proved ineffective. 24 women (80%), including 5 who did not obtain relief, indicated their wish to have sacral acupuncture during their next confinement. 2 women (6.7%) objected to needling, 3 considered acupuncture useless while another 2 did not believe in it. The patients' cardio-respiratory functions and uterine contractions were not adversely affected. There were no untoward effects on the mothers or their neonates. The procedure was technically simple, the equipment light and cheap. The needles did not interfere with nursing or obstetric manouvres. The procedure was however time consuming. The results were inconsistent and unpredictable. Despite these limitations, the simplicity, cheapness and absence of physiological complications associated with the procedure, make it a worthwhile medical armament for pain relief in the Nigerian environment, with limited resources and specialized manpower.

Acupuncture Therapy↗

PubMed1982

Experience with civilian vascular injuries in eastern Nigeria.

Accidents and trauma are the most common causes of death in the young Nigerian male. Due to inadequate facilities for recovering the injured, patients with major vascular injuries fail to reach the hospital alive. The incidence of vascular injury in the Nigerian population should be higher than is reflected in this study. Late presentation to the hospital results in the greater number of patients with traumatic aneurysms. Improvement in ambulance and hospital services for the injured will facilitate earlier detection and treatment of vascular injuries, improve the mortality rate, and limit the late sequelae of vascular injuries.

Accidents, Traffic↗

PubMedDate not supplied

A clinical evaluation of clavulanate-potentiated amoxycillin in the management of moderate to severe respiratory tract infections.

This study investigated the effects of clavulanate-potentiated amoxycillin in the management of moderate to severe respiratory tract infections. A total of 34 patients aged 10-70 years were studied to establish the clinical and bacterial efficacy of treatment and screened for unwanted effects and abnormal laboratory findings. Clavulanate-potentiated amoxycillin was given in dosages of 375 or 750 mg twice daily, orally, for a mean of 13 days (range 3-30 days). Patients were assessed at the end of 2 weeks and again on discharge from hospital (if later) for up to 6 months. Overall diminution in the number of symptoms was recorded at the end of the study; 78% of symptoms had disappeared after 2 weeks. The treatment proved highly effective in controlling respiratory tract infections in 94% of patients. The necessity for multiple drug therapy and parenteral administration was also avoided.

Adult↗

PubMedDate not supplied

Initial clinical experience with fazadinium bromide during anaesthesia in Nigerians.

Fazadinium Bromide (Fazadon, AH 8165), a non depolarising muscle relaxant, was injected into one hundred unpremedicated Nigerian patients requiring endotracheal intubation and prolonged skeletal muscle relaxation. The dose of Fazadon used was 1.5 mg per kg. body weight. Endotracheal intubation was possible in all the patients within thirty seconds of the intravenous injection of Fazadon. The initial single dose of the drug provided muscle relaxation for an average of forty minutes without the addition of any volatile anaesthetic agent. Arterial blood pressure was well maintained, but there was a mean increase in pulse rate of 20 beats per minute. Return of skeletal muscle activity was observed within one minute of the injection of neostigmine, in all but one patient.

Adolescent↗