[Pathogenesis, early diagnosis and treatment in tuberculosis of peripheral lymph nodes].
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Biomedical subjects
Publications and source records attributed to B V Shcherba.
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A total of 386 patients admitted with the diagnosis of tuberculous lymphadenitis were subjected to a differential diagnosis of tuberculosis of peripheral lymph nodes and malignant tumours. A histological examination of the removed lymph nodes demonstrated malignant tumours in 22 (5.7%) patients. Difficulties encountered in differentiating between tuberculous lymphadenitis and malignant tumours are due to changes in the clinical course of the process which are manifested in the enlargement of one or several nodes in 80% of patients in the absence of intoxication, which is also typical of primary malignant tumours of the lymph nodes. Histological and bacteriological studies of the removed nodes proved to be more informative for the differential diagnosis of tuberculous lymphadenitis and malignant tumours.
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Outcomes of shorter periods of treatment of patients with tuberculosis of the peripheral lymph nodes are presented. It is possible to reduce the period of treatment provided early surgical intervention is performed to remove the affected nodes. One recurring case detected after the long-term therapy. The counterindications for reduction of treatment periods of the above disease are generalization of the process and Mycobacterium resistance to tuberculostatic drugs.
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