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Biomedical subjects

B Vande Berg

Publications and source records attributed to B Vande Berg.

At least 19 recordsLinked to original sources

[Multiple diabetic muscular infarctions after liver and kidney transplantation: a case report].

INTRODUCTION: Several neuromuscular diseases may complicate diabetes mellitus and transplantation, including chronic sensorimotor length dependent polyneuropathy. OBJECTIVE: Description of muscular infarction, a rare complication of diabetes mellitus, which occurred after liver and kidney transplantation. CASE REPORT: A 57-year-old patient presented with long-term diabetes mellitus and multiple complications. End-stage renal and hepatic disease led to kidney and liver transplantation. Twenty-seven days after transplantation, swelling and induration appeared in the left shoulder and forearm. Forty-three days after transplantation, the same symptoms appeared in both lower limbs. Markedly reduced range of motion led to severe disability. Bone scans showed multiple spots following muscle anatomy. Computed tomography gave negative results. Magnetic resonance imaging (MRI) confirmed muscular infarction by a high T1 signal (muscular necrosis) and soft-tissue infiltration. DISCUSSION AND CONCLUSION: Muscular infarction is a rare and unknown complication of diabetes mellitus. It is characterised by sudden painful muscular induration and swelling affecting one muscle at a time with recurrence. Our patient presented with simultaneous multiple muscular infarctions in 3 limbs. Diagnosis was based on clinical investigation and MRI. The treatment is conservative and the condition generally resolved by itself. However, the long-term prognosis of muscular infarction is not good because of the cardiovascular-associated complications of diabetes mellitus.

Diabetes Mellitus, Type 1↗

[Juvenille papillomatosis].

The authors report a patient with juvenile papillomatosis of the breast presenting with a palpable mass and illustrate the correlation between mammographic, sonographic and pathologic features.

Adolescent↗

Post-renal transplant syndrome of transient lower limb joint pain: description under a tacrolimus-based immunosuppression.

The occurrence of a post-renal transplant syndrome of lower limbs joint pain has been reported extensively over the last decade. Clinical examination of the symptomatic joints is often unremarkable and magnetic resonance imaging reveals abnormalities of the bone marrow suggestive of edema and/or hemorrhage. The main striking features of this syndrome are the spontaneous resolution of the symptoms within a few weeks as well as of the marrow abnormalities. This syndrome has been attributed to cyclosporine, given in the immunosuppression regimen or to epiphyseal impactions. We here document the occurrence of this syndrome in 5 kidney graft recipients given a tacrolimus-based immunosuppression.

Adult↗

Costal cartilage fractures as revealed on CT and sonography.

OBJECTIVE: We describe the CT and sonographic appearance of 15 costal cartilage fractures observed in eight patients. CONCLUSION: On CT, fracture was seen as a low-density area through the costal cartilage, with surrounding calcifications present near old fractures, and gas density within the cleft in some cases. On sonography, cartilage fracture appeared as an interruption of the smooth anterior aspect of the cartilage.

Adult↗

Hematological changes in anorexia nervosa are correlated with total body fat mass depletion.

OBJECTIVE: To assess the relationships between total body fat mass (FM) and hematological abnormalities in anorexia nervosa (AN). METHOD: Peripheral blood parameters and body composition were determined in 10 anorectic patients and 19 age- and sex-matched healthy subjects. In patients with AN, magnetic resonance imaging (MRI) studies of bone marrow were also performed. RESULTS: Compared with controls, patients with AN had -41% body weight, -81% FM, -18.8% lean tissue mass (LTM), and -22.6% bone mineral content; they also had lower mean total leukocyte (4.52 +/- 0.47 vs. 6.28 +/- 0.33 x 10(3)/microliter, p < .005), neutrophil (2.45 +/- 0.34 vs. 3.46 +/- 0.20 x 10(3)/microliter, p < .005), monocyte (0.24 +/- 0.03 vs. 0.37 +/- 0.03 x 10(3)/microliter, p < .05), and platelet counts (184 +/- 17 vs. 238 +/- 9 x 10(3)/microliter, p < .005). Hemoglobin level was normal and comparable in both groups. In patients with AN, but not in controls, total leukocyte, neutrophil, eosinophil, and monocyte counts as well as hemoglobin level were highly correlated with FM expressed in absolute values or in percentage of body weight, but not with LTM. Moreover, AN patients with signal intensity patterns suggestive of serous atrophy of bone marrow at MRI had not only lower erythrocyte, leukocyte, neutrophil, and platelet counts, but they also had lower FM than AN patients with normal MRI patterns. DISCUSSION: Hematological changes in AN, as assessed by peripheral blood parameters and MRI patterns of bone marrow, are correlated with total body FM depletion, suggesting that the reduction of adipose tissue adversely affects hematopoiesis.

Adipose Tissue↗

Osteopenia, bone fragility and reflex sympathetic dystrophy syndrome in a man with ureterosigmoidostomy.

A 68-year-old man is presented with a reflex sympathetic dystrophy syndrome (RSDS) of the right ankle diagnosed by radiography, magnetic resonance imaging and bone scintiscan. Investigations, including blood tests and bone biopsy, revealed a diagnosis of metabolic acidosis and osteomalacia. These appeared to result from a ureterosigmoidostomy performed 9 years previously for a transitional carcinoma of the bladder. Correction of the metabolic acidosis coincided with improvement in ankle pain. RSDS may be the initial presentation of osteomalacia, which in turn may be caused by the metabolic acidosis resulting from a ureterosigmoidostomy.

Acidosis↗

Long-term effects of localized spinal radiation therapy on vertebral fractures and focal lesions appearance in patients with multiple myeloma.

The occurrence of new vertebral fractures and focal marrow lesions was determined and compared in irradiated and nonirradiated vertebrae of 12 patients with multiple myeloma (MM), prospectively followed using magnetic resonance imaging (MRI) of the thoraco-lumbar spine after localized spinal radiation therapy. During follow-up (mean 35 months), fractures appeared in 5% of irradiated vertebrae and in 20% of nonirradiated vertebrae: new focal lesions appeared in 4% of irradiated vertebrae and in 27% of nonirradiated vertebrae. This study demonstrates a beneficial long-term effect of localized radiation therapy, consisting of a reduced incidence of vertebral fractures and focal marrow lesions in irradiated vertebrae.

Aged↗

Injury to the brachial plexus by a fragment of bone after fracture of the clavicle.

Clavicular fractures are occasionally responsible for lesions of the brachial plexus. The symptoms are usually delayed and due to compression by hypertrophic callus, nonunion or a subclavian pseudoaneurysm. We describe a patient in whom a displaced bone fragment was pressing on the retroclavicular part of the brachial plexus, leading to early symptoms of a lesion of the posterior cord. Internal fixation of the clavicle and external neurolysis of the brachial plexus gave an almost full recovery.

Adult↗

[Radiologic aspects of the loosening of cemented hip prostheses: mechanical, septic or granulomatous etiology?].

Radiologic diagnosis of hip prosthesis loosening is based on the evaluation of each component (prosthesis, cement, bone) and of their interfaces. Both the prosthesis and the cement may deteriorate and the prosthesis/cement interface or cement/bone interface may become abnormal in prosthesis loosening of any etiology. In contrast, the aspect of the bone changes (erosion, periostitis) and their distribution vary according to the condition etiology. It appears from a retrospective study of 50 cases of chronic hip prosthesis loosening that the most specific signs for infection are unsharp bone resorption and acute-like or multifocal periostitis. In granulomatous loosening, bone resorption is sharp (as in mechanical loosening), but its distribution is not conform to the prosthesis shape (as in septic loosening), and periosteal changes are not observed.

Arthroplasty, Replacement, Hip↗

Recovery of red blood cell mass following orthognathic surgery.

The rates of recovery of red blood cell mass after surgery were compared in three groups of orthognathic surgery patients: 12 patients not receiving transfusions during Le Fort I osteotomy, 10 patients receiving transfusions during Le Fort I osteotomy, and 25 patients undergoing bilateral sagittal split osteotomy. Patients in these groups lost a mean of 421, 455, and 191 mL of blood, respectively, during surgery. Both groups of patients undergoing Le Fort I osteotomy donated a unit of blood prior to surgery, while the patients undergoing bilateral sagittal split osteotomy did not. A control group consisted of 77 presurgical orthognathic patients who donated a unit of blood (450 mL) a mean of 11 days prior to surgery. Among the control group, 38 had recovered red blood cell mass prior to surgery. The patients undergoing Le Fort I osteotomy recovered red blood cell mass after surgery more quickly than did the patients undergoing bilateral sagittal split osteotomy, despite having lost twice as much blood. This unexpected finding can be attributed to the need to lose sufficient red blood cell mass to stimulate the erythropoietic system. The patients undergoing Le Fort I osteotomy experienced two challenges to the system, predonation of blood and greater blood loss during surgery, resulting in a great enough decrease in red blood cell mass to stimulate the release of erythropoietin. Patients undergoing bilateral sagittal split osteotomy did not exceed this threshold. None of the differences among the groups were statistically significant, possibly because of the few number of subjects.

Adult↗