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Biomedical subjects

B Varkey

Publications and source records attributed to B Varkey.

67 records · Page 4Linked to original sources
PubMed1975

Allergic bronchopulmonary aspergillosis: an increasing clinical problem.

Allergic bronchopulmonary aspergillosis is being recognized with increasing frequency in the United States. The characteristics of the disease are recurrent pyrexia, cough, wheezing, sputum plugs containing aspergilli, fleeting pulmonary infiltrates, eosinophilia, dual skin reactions (immediate and late), and antibodies to the fungus in the blood. The pathogenetic mechanism is believed to involve type I and type III hypersensitivity reactions. Adrenal corticosteroids are effective in treating this condition.

Adrenal Cortex Hormones↗
PubMed1975

Deep mycotic infection in the hospitalized adult: a study of 123 patients.

A prospective study of patients hospitalized in a large Veterans Administration Hospital between November 1963 and November 1973 revealed 123 patients with deep mycotic infections. The incidence of these infections almost doubled during the last 5 years. Candida (55 patients) and Aspergillus (26 patients) were the major causative agents. Nine other fungal caused infection in the remaining patients. Candidemia was rare prior to the introduction of commerical percutaneously-inserted venous catheters in 1965. The incidence increased further following the introduction of parenteral hyperalimentation in 1969, and Torulopsis fungemia (5 patients) appeared for the first time. Invasive pneumonia caused by spore-forming Aspergillus decreased when patients were moved from an old, naturally-ventilated hospital to a new, mechanically-ventilated one. The air in both hospitals was sampled on one occasion for the presence of fungal spores, and spores of Aspergillus fumigatus were detected only in the old hospital. Our experience suggests that hospital-acquired Aspergillus infection of the lung might be eliminated if all incoming hospital air is filtered, properly vented, and not recirculated. Efforts to decrease hospital-acquired fungal infections include vigorous infection control procedures for intravenous therapy, judicious use of any therapy that predisposes to infection, and further evaluation of improved mechanical control of hospital ventilation.

Adult↗
PubMedDate not supplied

Malignant-appearing cells in pleural effusion due to pancreatitis: case report and literature review.

Malignant-appearing mesothelial cells were noted in an amylase-rich pleural effusion caused by pancreatitis in the absence of any neoplastic disease. Such changes in the mesothelial cells are believed to be the result of intense irritation of the serosal surfaces by the pancreatic enzymes. Review of the literature showed a likelihood of false-positive cytologic diagnosis of 0.44% for pleural effusions and 0.91% for all serous effusions. Because of the potential for serious error in patient management based on a false-positive cytology, it is important to recognize the conditions that may be responsible for it.

Diagnosis, Differential↗