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B Velasco Sánchez

Publications and source records attributed to B Velasco Sánchez.

8 recordsLinked to original sources
PubMed2003

[Apoptosis in the cryptorchidism. Role of the FAS protein in it's modulation].

The cellular degeneration, present at the criptorchidism leads to a malfunction in the spermatogenosis and it's due to cellular apoptosis (programed cellular death). This process is turned on and modulated by different ways. One of then is mediated by Ag-Ac reactions and a protein called FAS seems to have an important role in it's modulation. We studied the relation between FAS an the increased apoptosis in undescended testics. Testicular biopsies were done in criptorchid patients during orchidopexy and FAS was measured by immune-techniques. Our results seem to dismiss FAS as a modulation apoptosis factor in the cryptorchidism.

Apoptosis↗
PubMed2002

[Modifications of gastric distensibility as a function of the type of fundoplication. Experimental model in rats].

UNLABELLED: Gastric fundoplication to create an antireflux valve reduces gastric volume. The most widely used technique is Nissen's fundoplication (NF), but an anterior (AF) and posterior (PF) partial fundoplication are also used. This study examines the changes caused by these three techniques on the volume and the compliance of the stomach in vitro. MATERIAL AND METHODS: We used 4 groups of 10 rats Wistar each, weighing approximately 250-300 grams. One group was not manipulated (Control) whereas the other groups had NF, AF or PF respectively. The fresh stomachs were removed and progressively filled with saline by means of an infusion pump and the intragastric pressure was continuously measured with a pressure monitor. The volume of saline infusion required necessary to achieve pressure increments of 1 unit from 0 to 30 mmHg were measured and the results were compared with ANOVA. RESULTS: The three modalities of fundoplication reduced significantly gastric compliance since rats from the control group required 21.7 +/- 3.3 mL to reach intragastric pressure of 30 mmHg whereas 9.5 +/- 2.4 mL, 11.75 +/- 1.8 mL and 13.4 +/- 2.2 mL were required for the groups NF, AF and PF respectively. According to these results, the type of fundoplication which reduced the least the compliance was the posterior one. CONCLUSIONS: The use of fundus of the stomach to create an antireflux valve always implies a significant reduction of gastric compliance, which can favour gastric emptying and thus dumping syndrome. Even though important, this reduction was slightly less relevant after posterior fundoplication in this model. This evidence must be taken into account when choosing an antireflux technique.

Animals↗
PubMed2002

[Treatment of psoas abscess. Report of a case and review of the literature].

Psoas abscess is an infrequent disease. We present a right psoas abscess diagnosed in a thirteen-year-old child. There wasn't a history of known trauma nor immunodeficiency. We didn't find another infection focus so the abscess was described as primary one. This is the most commonly presentation in children. Staphylococcus aureus was the bacteria identified in blood culture. The presenting symptoms were bottom and hip pain, limp and fever. The differential diagnosis was established with suppurative arthritis of the hip. Diagnosis was confirmed by Magnetic Resonance. In regard to treatment the patient was exclusively treated with systemic antibiotics, high spectrum of activity. The patient didn't require percutaneous-drainage. Though surgical drainage wasn't made, evolution was favourable and recurrence wasn't observed.

Adolescent↗
PubMed2000

[Progressive acquired lymphangioma: report of a case and review of the literature].

We present 2-year-old patient with a allopecia lesions in scalp, and clinique diagnostic of Cutis Aplasia. The anatomopathologic study have diagnosed the lesions as Acquired Progressive Lymphangioma (APL). Is a rare vascular tumour that has a tendency to appear in childhood an to progress slowly over the years. It could present as a solitary erythematous macule or plaque and a simple excision is usually curative. Our patient is the youngest reported in the literature.

Child, Preschool↗
PubMed1997

[The use of a continent urinary stoma in complex reconstructions of the lower urinary tract in children].

Since its description in 1980, the Mitrofanoff principle has become a widely utilized and successful technique for the management of patients with a variety of urological disorders. We report our experience with this procedure in 14 patients (10 M, 4 F). The age range was 3.5 years to 17 years (average 12 y) and follow-up was from 6 months to 3 years (average 1.7 y). Patients were classified in 2 groups: I) When this procedure was done because of the patient was unable to perform urethral catheterization (8p). II) Concomitant bladder neck transection and Mitrofanoff diversion (6p). The appendice was used in 9p, ileum in 1 and ureter in 4. Bladder augmentation was performed with ureter in 2p and colon sigmoid in 4. In 1p, ileo-cecal segment and in other colon+ileum, were used to replace the bladder. All patients catheterize the Mitrofanoff channel easily, there were no case of stomal stenosis and the conduit was continent in all. We consider that Mitrofanoff principle is a very successful technique and it can be used as the primary continence mechanism or as an adjunct of major urinary tract reconstruction, to ensure complete bladder emptying, in patients unable to perform urethral catheterization.

Adolescent↗
PubMed1997

[Neutropenic enterocolitis in children with cancer].

OBJECTIVES: Neuropenic enterocolitis (NEC) is a destructive lesion of the ileocecal region occurring in cancer patients treated with chemotherapy. Its clinical picture is one of febrile acute abdominal extension with bloody diarrhea and low neutrophil counts. Our aim was to determine the incidence of NEC in children with cancer and to review the indications of surgery in these cases. MATERIAL AND METHODS: The records of children with cancer treated with chemotherapy in the last 6 years at Hospital Infantile La Paz were reviewed. We selected those patients who had abdominal pain and neutropenia and whose physical examination and radiological findings were consistent with NEC. RESULTS: Twelve cases of NEC were diagnosed during this period among 432 malignancies. The symptoms most frequently seen were abdominal pain and distension, nausea and vomiting. The neutrophil count was consistently below 500/ml. All patients were receiving chemotherapy before the onset of the clinical picture. Five children were operated upon. In three of these we found various ileocecal perforations, in one a gastric perforation and in the remaining one a diffuse inflammation of the ileocecal area. Two non-operated patients died from NEC. The remaining children recovered without problems with medical therapy. CONCLUSION: Pediatric surgeons treating neutropenic cancer patients should be familiar with this condition, that must be suspected early in granulocytopenic patients with acute abdominal extension. Aggressive surgical management is indicated in cases with severe peritonitis, bowel perforation or massive lower gastrointestinal bleeding, irrespective of the degree of neutropenia. Medical support should aim at reestablishing normal neutrophil counts.

Adolescent↗