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Biomedical subjects

B Vion

Publications and source records attributed to B Vion.

16 recordsLinked to original sources

Cutaneous plasmacytosis: an unusual presentation sharing features with POEMS syndrome?

Cutaneous plasmacytosis is a recently described skin disorder consisting of brown to red papules and nodules containing polyclonal plasmacytes. In this particular case, leg ulcers developed but also a diffuse patchy hyperpigmentation coexisting with a primary hypothyroidisim. The last two signs have only been described to date in POEMS syndrome, which is linked to monoclonal plasmacytic proliferation, and might suggest an overlap between these two entities.

Aged↗

Angiosarcoma of the scalp. A case with a particularly aggressive evolution.

A 80-year-old woman presented with a spontaneously bleeding wound on her scalp. The diagnosis of angiosarcoma was made based on histopathological examination of the second biopsy 1 month later. At that time, a large hematoma was present on the scalp and forehead with two bleeding erosions and numerous small blue-black nodules as well as a right cervical lymphadenopathy. The patient was treated by wide-field electron-beam radiotherapy, which showed no effect. The particularly aggressive evolution of this angiosarcoma led to death within less than 2 months.

Aged↗

Neutrophilic eccrine hidradenitis.

We report an additional typical case of neutrophilic eccrine hidradenitis, which was observed in a 57-year-old man with acute myelogenous leukemia. He developed this eruption following chemotherapy with cytarabine and mitoxantrone. A short review of the literature is presented.

Antineoplastic Combined Chemotherapy Protocols↗

Delayed skin reaction caused by a coelenterate.

We report a delayed skin reaction, histologically characterized by liquefaction degeneration of the basal layer, which was observed in a 30-year-old man returning from Guadeloupe. It was most likely due to contact with a marine animal.

Adult↗

Tufted angioma.

The clinical and histological description of 2 cases of tufted angioma is presented.

Diagnosis, Differential↗

Melanoacanthoma of the penis shaft. Report of a case.

We report an additional case of melanocanthoma, a rare benign mixed tumor of both keratinocytes and melanocytes occurring in a 66-year-old man on the penis shaft, a localization not previously described. Clinical and histological features are briefly discussed.

Aged↗

Generalized eruptive pustular drug rash due to cephalexin.

A 38-year-old woman developed a generalized pustular eruption 18 h after taking an oral cephalosporin (cephalexin). After having excluded other possible pustular dermatoses, we concluded that our patient's eruption was drug-induced.

Adult↗

[Developmental aspects of nevus spilus: review of the literature apropos of 7 cases].

The nevus on nevus is a dischromic lesion with a double component made of a pigmented, pale-brown coloured spot, most often congenital punctuated by macular or discretely papular darker elements, with a usually later setting-up and conventionally characterized by an absence of evolutivity. A series of seven cases is reported of whom three present a very peculiar evolution: A 37 years old man is taking a medical advice for a nevus on a congenital nevus on the right buttock on which appeared later on a blue-coloured, lightly sensitive nodule which clinically calls to mind the diagnosis of a blue nevus: the surgical exeresis is refused by the patient. A little girl, born in 1972, has since her birth a nevus on nevus of her right fore-arm; in 1975 and 1976 appeared successively on this lesion three nodules evocative of Spitz melanoma (fig. 4), which are surgically removed; histologic examination confirms the clinical diagnosis (fig. 5). A woman, aged 38, presents a big nevus on congenital zosteriform nevus of the right lower limb; since 1982, one of the dark elements situated on the lower third of the leg is progressively spreading and becoming polychromic (fig. 6); the clinical suspicious of superficial spreading malignant melanoma is confirmed by the histologic examination. In the literature, the terminology aiming to call this kind of nevic pale brown spot recovered by darker macules is not quite clear, as it was already emphasized by Stewart in 1978 (27). Indeed, numerous different denomination are found in it: "nevus spilus", nevus on nevus", "spotty nevus" "speckled lentiginous nevus", "speckled nevus "spilus".(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗