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Biomedical subjects

B Vucelić

Publications and source records attributed to B Vucelić.

At least 37 records · Page 2Linked to original sources
PubMedDate not supplied

Assessment of value of pancreatic pseudocyst amylase concentration in the treatment of pancreatic pseudocysts by percutaneous evacuation.

The aim of our study was to determine the value of the percutaneous pancreatic pseudocyst evacuation. We assessed the relation between the amylase concentration of the pseudocyst contents and the final outcome of the disease treated by the percutaneous evacuation. Forty-three patients with a history of acute pancreatitis and pancreatic pseudocysts larger than 5 cm in diameter that persisted beyond 6 weeks were divided into four groups relative to the amylase concentration in the pseudocystic contents and the number of evacuations. The results show a good correlation between low amylase concentration in the liquid pseudocystic contents (less than or equal to 64 WU) and the healing rate after the percutaneous evacuation (p less than 0.001). The percutaneous evacuation of the pseudocysts failed in patients with increased amylase concentrations in the pseudocyst fluid regardless of the number of evacuations. We conclude that surgical treatment is indicated in patients who have amylase-rich pseudocyst contents.

Adult↗
PubMedDate not supplied

[Pseudomyxoma peritonei associated with splenic mucinous epithelial cysts--case report].

A massive gelatinous ascites occurred in a 60-year-old patient, with no primary tumor found in the clinical work-up. The malignant cells were not found in the cytological examination of ascites. Explorative laparotomy revealed a gelatinous mass of 14 kg, a cystic tumor of the omentum and an identical cystic tumor of the spleen's lower pole. It was a well differentiated mucinous cystadenocarcinoma, most likely originating in the appendix. Most interesting is the involvement of the spleen with mucinous epithelial cysts, described as a rare finding associated with pseudomyxoma.

Cystadenocarcinoma, Mucinous↗
PubMedDate not supplied

[Acute psychoses caused by digitalis poisoning].

The course of illness in a 76-year-old woman with a history of dyspnea being treated with medigoxin, 0.1 mg daily, is presented. Five days before the symptoms of acute psychosis developed she had used medigoxin, 0.2 mg per day. On the fifth day of that therapy, the patient developed acute psychosis and was admitted to the Department of Psychiatry. An electrocardiogram recorded monomorphous ventricular premature beats at a frequency of 50%, the S-T segment depression of the anterolateral location with the diphasic T-wave and the corrected Q-T interval of 0.377 to 0.355 seconds. Five days after the discontinuation of medigoxin therapy, serum digoxin concentration was 2.2 nmol/L, out of which follows that two days after digitalis was stopped it was 4.0 nmol/L and that concentration was probably higher at the moment when acute psychosis developed. The patient was free of symptoms of acute psychosis after a single promazine dose and discontinuation of medigoxin.

Acute Disease↗
PubMedDate not supplied

[Stress erosions and ulcers].

The modern concept of the etiopathogenesis of stress erosions and ulcers is given in this paper. The importance of prophylaxis is emphasized due to the very complex problems of treating wounded in situation where medical institutions are being intentionally damaged and where delayed evacuation is a common occurrence.

Humans↗
PubMedDate not supplied

[Biliary calculosis--new possibilities of treatment].

The gallstone prevalence rate in Croatia is in the range of 10 to 20 per cent and for the population above age 65 years is around 30 per cent. Human gallstones are classified into two categories, i.e. cholesterol stones and pigment stones. Cholesterol stones account for 70-80% of gallstones. They are formed due to the bile supersaturation with cholesterol and later nucleation of cholesterol vesicles and crystal formation. Pigment stones of black type account for 20-25% of gallstones. They are formed as a result of chronic hemolysis. Surgery is still a method of choice in treatment of majority of patients with gallstones. It is a low-risk therapy with high success rate that can be used regardless the size, number, composition and localisation of gallstones. Cholesterol stones can be dissolved by direct instillation of methyl tert-butyl ether (MTBE therapy), fragmented by extracorporeal shockwaves (ESWL) and dissolved using bile salts chenodeoxycholic acid and ursodeoxycholic acid. The problems with these treatment modalities is high recurrence rate and limitation described for each method. Choledocholithiasis can be treated surgically, by endoscopic sphincterotomy combined with stone extraction and by extraction via T-tract. The decision on the best treatment modality in gallstone patients should be made only after careful evaluation of all relevant facts (type of stone, number and size of stones, localisation of stones, patient's age and general condition) taking into consideration the team experience. It is imperative not to use the treatment method with possible complication that cannot be dealt with in the institution performing the treatment.

Bile Acids and Salts↗
PubMedDate not supplied

[Value of C-reactive protein in the evaluation of activity in ulcerative colitis and Crohn's disease].

We studied a value of measuring the C-reactive protein (CRP) serum concentration in the assessment of ulcerative colitis and Crohn's disease activity. From a large register of patients with the inflammatory bowel disease (IBD), we have chosen randomly 91 patients: 61 with ulcerative colitis and 30 with Crohn's disease. As a reference point in the assessment of ulcerative colitis we have used the Powell-Tuck clinical index. Nineteen patients had an active disease, and 42 were in a remission. Patients with the active disease had significantly higher levels of the CRP then the patients in remission (chi 2 = 4.99; alpha less than 0.05). Serum CRP levels and the disease activity assessment by Powell-Tuck index were in a positive correlation, according to the Fisher's exact test (p less than 10(-8)). In the group of 30 patients with Crohn's disease, the disease activity was assessed by CDAI ("The Crohn's Disease Activity Index") and by van Hees index. According to CDAI, 26 patients were in a remission, and only 4 had an active disease. According to van Hees index, there was no patient in a complete remission, 17 patients had a partial remission and 13 had an active disease. Patients with the active disease had significantly higher CRP levels then the patients in remission, according to van Hees index (chi 2 = 7.863; alpha less than 0.01), but not according to CDAI (not significant). Meanwhile, the Fisher's exact test suggested a high positive correlation between the disease activity assessment with both indexes, either CDAI or van Hees, and the CRP serum values (alpha less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

C-Reactive Protein↗
PubMedDate not supplied

[Cigarette smoking and ulcerative colitis--is there a causal relationship?].

The relation between cigarette smoking and ulcerative colitis was assessed in a case-control study of 235 cases of ulcerative colitis and 311 age- and sex-matched control subjects admitted to the hospital for conditions unrelated to smoking. Smoking habits and daily number of cigarettes smoked were analysed. We found significantly less number of smokers and more ex-smokers in the ulcerative colitis group. The intensity of smoking was equal in both groups. It was noted that pancolitis occurred more frequently in the ex-smokers group. The intensity of smoking did not influence the extension and clinical course of ulcerative colitis. For ulcerative colitis, the relative risk for nonsmokers was 7.4. The study revealed a positive correlation between nonsmoking and ulcerative colitis, higher incidence of pancolitis among ex-smokers and higher relative risk of ulcerative colitis for never-smokers. Various possible causes of influence of smoking on ulcerative colitis are discussed.

Adolescent↗
PubMedDate not supplied

[The effect of atmospheric conditions on the occurrence of peptic ulcer hemorrhage].

The influence of atmospheric factors on the frequency of bleeding from the peptic ulcer was studied within the period from April 1, 1984, to March 31, 1989, consequently through 1826 days. The average daily atmospheric pressure, the average daily temperature and the relative humidity have been examined. There were 1102 cases of bleeding peptic ulcer, 537 bleeding gastric ulcers and 565 bleeding duodenal ulcers. During the study period there were 454 days with bleeding form ventricular ulcer and 465 days with bleeding from duodenal ulcer. There was 793 days with bleeding form either lesion. The discriminatory analysis demonstrated that the atmospheric pressure is the variable that discriminates the days with bleeding and the days prior to bleeding from the days without bleeding. The relative humidity occurs as the relevant discriminatory variable in the days prior to bleeding for the duodenal ulcer group and for the entire group. The centroids of the discriminatory function demonstrate that the days with ulcer bleeding are characterized by the fall of atmospheric pressure. The factor analysis of meterological variables clearly shows the correlation of the atmospheric pressure and the bleeding regardless to the localisation of bleeding ulcer, where the greatest number of bleedings is correlated with lower atmospheric pressure. We conclude that the incidence of bleeding form the peptic ulcer of the stomach and duodenum correlates in great measure with low atmospheric pressure in the days prior to bleeding and in the days of bleeding, as well as with fall of atmospheric pressure in the days of bleeding with respect to previous day.(ABSTRACT TRUNCATED AT 250 WORDS)

Atmospheric Pressure↗