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Biomedical subjects

B W Codling

Publications and source records attributed to B W Codling.

31 records · Page 2Linked to original sources

Five year follow-up study of gastritis.

This paper describes a five year follow-up study of the incidence and course of gastritis affecting the antrum and body of the stomach of 50 patients, most of whom presented with non-ulcer dyspepsia and a few with peptic ulceration. We have shown that antral gastritis, like gastritis affecting the fundus, becomes more severe in a proportion of patients as time goes by. Perhaps more important is the increased severity and progression of atrophic and metaplastic change in the antrum compared with the fundus. The significance of these changes with regard to the development of peptic ulceration and malignancy is discussed.

Adult↗

Use of a histopathology data pool for epidemiological analysis.

Data from the Birmingham Histopathology Data Pool of surgical pathology on the age, sex, and site distributions of various cutaneous and hepatic lesions have been analysed, and the results have been compared with data from the Regional Cancer Registry. Analysis of malignant neoplasms shows that there is no significant difference between the two sources. The results are discussed with reference to the potential use of histopathology data banks for quality assurance in histopathology and epidemiological analysis.

Adolescent↗

The Birmingham Histopathology Data Pool: a co-operative project among 10 laboratories.

In 1970 the Birmingham Histopathology Data Pool was established to collect information on biopsies of surgical specimens from three hospitals. The scheme has gradually expanded and 10 hospitals now participate. The pathologist gives each specimen a numerical code based on the Systematised Nomenclature of Pathology (SNOP). The information is processed by computer and stored on cumulative magnetic tape file. At regular intervals (at three, six, and nine months) 'printouts' listing all the information recorded within the interval are produced and a cumulative print-out is issued when the information for a whole year is complete. The data pool system has provided accurate alphabetical and SNOP diagnostic files and has simplified retrieval of data for both follow-up and research purposes. The pathologist may use the computer to retrieve and analyse information from the data pool for this own use or on behalf of clinicians, but he may use information from laboratories other than his own for research purposes and publication only with the permission of the pathologists who submitted the data.

Electronic Data Processing↗

An on-line computer system for histopathology reporting.

An on-line computer system was developed for issuing histopathology reports as part of an integrated hospital information system. Input is through a Cossor visual display unit with a typewriter keyboard to a Univac 418 III computer. Stored information is available to authorised hospital staff via similar visual display units located in the wards and laboratories. Existing programs and computer staff were used to provide the new service. It has resulted in better method, speedier communication, and saving of laboratory staff time. The system has yet to be fully tested but initial reactions are favourable and indicate that the investment in computer staff time and extra laboratory equipment will be cost effective.

Online Systems↗

Hodgkin's disease complicating Crohn's colitis.

A case of Hodgkin's disease involving an area of Crohn's colitis in a patient with a 20-year history of inflammatory bowel disease is described. The coexistence of Crohn's disease and Hodgkin's lymphoma has not been reported previously. The possible relationship between gastrointestinal lymphoma and Crohn's disease also is discussed.

Adult↗

Pulmonary fibrosis following therapy with Melphalan for multiple myeloma.

A patient suffering from multiple myeloma developed pulmonary fibrosis, of a type known to be associated wtih busulphan, whilst being treated with Melphalan. The possible role of Melphalan as the causative agent is discussed. Reference is made to other possible aetiological agents and the reasons for their exclusion are discussed.

Autopsy↗