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Biomedical subjects

B W Hindman

Publications and source records attributed to B W Hindman.

9 recordsLinked to original sources
PubMed1998

Langerhans cell histiocytosis: unusual skeletal manifestations observed in thirty-four cases.

OBJECTIVE: Unusual manifestations are occasionally encountered in Langerhans cell histiocytosis and may be a source of confusion. The objective of this study was to determine the frequency of occurrence of the unusual manifestations in our case material. DESIGN AND PATIENTS: Thirty-four children, average age 4.4 years (range 3 months to 16 years) with 262 skeletal lesions of biopsy-proven Langerhans cell histiocytosis (LCH) were retrospectively reviewed to determine the frequency of occurrence of unusual manifestations defined either as an atypical location of a skeletal lesion or an atypical radiographic appearance of the lesion. RESULTS: Twenty-four unusual lesions were found in this retrospective review. Among these were epiphyseal lesions, transphyseal lesions, extracranial 'button' sequestra, posterior vertebral arch lesions, dural extension of vertebral lesions, and fluid-fluid levels. The finding of fluid-fluid levels has not previously been described in the radiologic literature. Involvement of unusual sites included clavicles and small bones of the hands and feet. CONCLUSIONS: Radiographic, computed tomographic, and magnetic resonance imaging of LCH yield a variety of unusual manifestations. Recognition of these varied appearances of LCH may prevent confusion of such appearances with other pathologic processes. When the unusual manifestation occurs as the initial finding of the disease, LCH should be included in the differential diagnosis.

Adolescent↗
PubMed1997

Primitive neuroectodermal tumor in a child with tuberous sclerosis.

The case of a 13-year-old boy with tuberous sclerosis and primitive neuroectodermal tumor of bone is presented. A pathogenetic association between these two entities is postulated, the unifying underlying mechanism being a maldevelopment of the neural crest, or neurocristopathy.

Adolescent↗
PubMed1996

Neonatal osteofibrous dysplasia: report of two cases.

Skeletal neoplasms of the newborn and neonatal period are infrequently encountered and often misdiagnosed. Osteofibrous dysplasia is a tumor of childhood that may be seen in the newborn. Because of its unique natural history, with and without surgical treatment, and the similarity in radiographic appearance of this tumor to other lesions, a high index of suspicion must be maintained when a tibial lesion is encountered in the newborn. We present two additional cases of neonatal osteofibrous dysplasia and discuss the differential diagnostic considerations.

Diagnosis, Differential↗
PubMed1994

Multicentric giant cell tumor: report of five new cases.

The typical giant cell tumor (GCT) is a solitary neoplams that occurs in the epiphysis or epimetaphysis of long bones. GCT is seen with a slightly increased frequency in females, and 70% of patients are between 20 and 40 years of age at the time of presentation. Multicentric giant cell tumor (MGCT; two or more centers) is an unusual variant of GCT. Patients with MGCT are likely to be younger than those with a solitary lesion. The multicentric variety is often of a higher stage at diagnosis and is more often associated with a pathological fracture than the unifocal tumor. We are reporting five new cases of MGCT, with a total of 21 tumors seen over a period of 25 years from 1967 to 1992.

Adolescent↗
PubMed1989

Occult fractures of the carpals and metacarpals: demonstration by CT.

Occult fractures of the carpals and metacarpals occur frequently and are associated with major disability. The cross-sectional display and superior resolution of CT are well suited to the demonstration of these fractures. Sixteen patients with pain and negative conventional radiographs were chosen for further evaluation by CT. Imaging was performed in two planes and showed 21 fractures. The transaxial plane was the most revealing imaging plane. Coronal imaging was equal or superior to the transaxial plane in most fractures of the scaphoid, lunate, capitate, and pisiform bones and of the bases of the metacarpal bones. The direct sagittal plane was the best imaging plane in one patient with fractures of the scaphoid and lunate bones. After discovery of the fracture on CT, surgical removal of the avulsed fracture fragment was recommended in seven patients and fusion was recommended in three. Eight patients had a marked decrease in pain after the surgical procedure. The accuracy of CT for the demonstration of occult fractures may result in earlier recognition of these fractures and a reduction in the associated disability.

Carpal Bones↗
PubMed1988

Supracondylar fractures of the humerus: prediction of the cubitus varus deformity with CT.

Rotation of the distal fracture fragment in the supracondylar fracture is a contributing factor in the development of the cubitus varus deformity. Computed tomography (CT) is superior to conventional radiography in the assessment of the position of fracture fragments and was used to study 20 patients with supracondylar fractures after reduction. These fractures were followed up with radiography until healed. As determined from CT scans, rotation of the distal fracture fragment of greater than 10 degrees resulted in an abnormal Baumann angle and a cubitus varus deformity in all patients. Use of CT should facilitate the identification of this complication and thus treatment of these fractures and prevention of subsequent deformity.

Child↗
PubMed1986

Fractures of the talus and calcaneus: evaluation by computed tomography.

Fractures of the talus and calcaneus may be difficult to evaluate using conventional imaging modalities. Failure to recognize these fractures or to appreciate their extent may result in severe deformity or disability. Patients with talar and calcaneal fractures had computed tomography to assess its role in the management of these fractures. Computed tomography is superior to other imaging modalities in showing the position of the fracture fragments, the number of fragments, the relation of the fracture to the articular surfaces, residual articular changes, and evidence of healing.

Calcaneus↗
PubMed1980

Ultrasound in the evaluation of small bowel lymphoma in children.

In seven children with small bowel lymphoma, gray scale ultrasound correctly identified the pathological process, as well as excluded the kidney, liver, and adrenal as the site of origin. In all cases, thickened bowel wall and exoenteric masses were identified. Surgical confirmation was obtained in all patients.

Barium Sulfate↗