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Biomedical subjects

B W Lagerveld

Publications and source records attributed to B W Lagerveld.

3 recordsLinked to original sources

Cryotherapy for renal-cell cancer: diagnosis, treatment, and contrast-enhanced ultrasonography for follow-up.

Cryotherapy is a curative treatment option for patients with small (<4 cm) renal-cell cancers. For the followup of ablated lesions, imaging is the only available method, but the best tool has not yet been determined. The method selected should be able to determine the presence or absence of perfusion in the area and measure the lesion. Usually, contrast-enhanced CT or MRI is used. The accompanying video shows cryotherapy treatment along with contrast-enhanced ultrasound investigations before and afterward. We used a Siemens Acuson Sequoia device with contrast pulse sequence imaging and Sonovue (Bracco) as the contrast agent. The lesion could be identified and measured easily. Because this method enables selective detection of contrast, the presence and absence of perfusion can be determined objectively.

Carcinoma, Renal Cell↗

Testicular granulocytic sarcoma without systemic leukemia.

This case report describes a unilateral testicular granulocytic sarcoma or chloroma. Because of the relatively immature nature of the tumor cells, the histological diagnosis can be difficult. Granulocytic sarcomas are well known in patients with systemic leukemia and can sometimes precede a systemic leukemic outcome. A solitary granulocytic sarcoma not followed by a hematological proliferation of the myelocytic stem cells is very rare. No prognostic factors that are able to predict a systemic outcome are known. Therefore, in this case with no signs of systemic disease, we adopted a wait-and-see policy after radical orchidectomy. Up to now, after a follow-up period of 7 years, the patient is still free of disease. Diagnosis and therapy of this urologic disease are discussed and the literature is reviewed.

Biopsy↗

Long-term results after external beam radiation therapy for T1-T2 localized prostate cancer.

The incidence of organ-confined and early-stage prostate cancer has increased. The external beam radiation therapy has proven to be a good therapeutic option in terms of biochemical survival and overall survival. It has been modified throughout the years; consequently, the available data on the long-term efficacy of external beam radiation therapy are difficult to compare with the commonly used improved radiation strategies. Intensity-modulated conformal radiotherapy and three-dimensional conformal radiotherapy result in better tumor control at a lower complication rate. External beam radiotherapy seems to be favored in intermediate- and high-risk groups for relapse of prostate cancer and radical prostatectomy is favored in the low-risk group. However, they score similarly in terms of general health-related quality of life after treatment.

Health Status↗