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Biomedical subjects

B W Zhou

Publications and source records attributed to B W Zhou.

7 recordsLinked to original sources
PubMed1994

[An epidemiologic study of workers with low back pain].

To evaluate the impact of low back pain we conducted a cross-sectional epidemiologic study of 10087 workers in factories of textile, machinery auto-transportation, clothing and sea cultivation. The prevalence of pain was compared with ages, sexes, duration of employment, types of jobs as well as body posture. The prevalence of low back in males was 13.66%, and in females 8.75% (average 11.53%). The risk factors included lifting, bending, twisting prolonged sitting and vibration as well as moisture and coldness prolonged sitting was. The important contributing factor of low back pain in sedentary workers.

Adult↗
PubMed1989

[Preoperative management of scoliosis by positioning the trunk on its convex side].

A new method, hanging the scoliotic trunk on its convex side, for preoperative management of scoliosis was described and has been used on 36 patients with good result. The weight used varied individually from 10 kg to 40 kg to lift the convex side 5 to 8 cm above the bed surface on which he or she lay. Hanging in this way in about 2 weeks would stretch out and relax the soft tissues on the convex side, resulting in maximum correction. This method is simple, effective and without side effect. We would think that it is an ideal way for preoperative correction of idiopathic scoliosis.

Adolescent↗
PubMedDate not supplied

Recognition of alternating oligopurine/oligopyrimidine tracts of DNA by oligonucleotides with base-to-base linkages.

A new concept is presented to design and synthesize modified oligonucleotides in order to extend the range of double-helical DNA sequences that can be recognized by oligonucleotides via triple helix formation. The DNA target is composed of adjacent oligopurine.oligopyrimidine domains where the oligopurine sequences alternate on the two DNA strands. Canonical (C,T)-motif triple helices are formed with each oligopurine.oligopyrimidine domain of the target sequence. The two third-strand oligonucleotides were joined together via an appropriate linker between the two terminal bases with either a 3'-3' or a 5'-5' polarity. Molecular modeling was used to predict the optimal length of the linker bridging two terminal bases. The interaction of DNA with such a modified oligonucleotide containing a C3'-3'U linkage was studied by thermal dissociation, footprinting, and gel retardation experiments. They provide experimental evidence that the oligonucleotide does form a switched triple helix on this extended DNA target sequence. The binding of the so-called "switch oligonucleotide" is enhanced as compared to the two unlinked parental oligonucleotides which form triple helices with each oligopurine.oligopyrimidine domain of the target sequence.

Base Sequence↗