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Biomedical subjects

B Woźniewicz

Publications and source records attributed to B Woźniewicz.

72 records · Page 4Linked to original sources
PubMedDate not supplied

Primary hyperparathyroidism in infants. Diagnostic and therapeutic difficulties.

On the basis of 3 infants with primary congenital hyperparathyroidism we discuss problems in the early diagnosis and interpretation of the results of laboratory findings. The lack of increased renal echogenicity and hypercalciuria, which is regularly present in idiopathic hypercalcaemia is emphasized. In contrast to secondary hyperparathyroidism caused by prolonged hypocalcaemia, e.g. in patients treated by longterm haemodialysis, the aetiology of primary hyperparathyroidism (pHPT) remained unclear although molecular genetic studies suggest that the development of parathyroid adenoma may be due to gene mutation in a cell. Congenital pHPT is a particularly rare condition usually due to diffuse hyperplasia of all parathyroid glands. Its inheritance is known to be autosomal. Three infants with congenital primary hyperparathyroidism were treated at the Child Health Centre in the years 1987-1988.

Diagnosis, Differential↗
PubMedDate not supplied

Rashkind's operation in treatment of complete transposition of the great vessels in the newborn and infants.

The study is a result of many years investigations of a large pediatric team consisting of physicians from various specialities on the methods of management in cases of transposition of greater arterial vessels. Trials of surgical treatment requiring thoracotomy in the newborn with severe cardiorespiratory failure gave no good results. In recent years 65 operations of atrioseptostomy without thoracotomy were carried out during cardiac catheterization. In nearly half the cases improvement of the general condition was obtained with survival for several months or even over one year, but close supervision was required and the children were being prepared for more radical cardiosurgical operations.

Female↗
PubMedDate not supplied

Procollagen type III peptide in the assessment of liver fibrosis in children with congenital alpha-1-antitrypsin deficiency.

In 31 children with congenital alpha 1-antitrypsin deficiency the concentration of procollagen type III peptide was determined in a trial establishing liver fibrosis degree and monitoring of fibrosis progression. No correlation was found between the degree liver fibrosis determined by histological examination and the serum concentration of procollagen type III peptide. The concentration of procollagen type III peptide was higher with coexistent cholestasis and in case of inflammatory processes outside the liver (pneumonia). In progressing cirrhosis with inflammatory reaction the concentration was higher than in advanced cirrhosis and non-inflammatory liver fibrosis.

Adolescent↗