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Biomedical subjects

B Wolcott

Publications and source records attributed to B Wolcott.

5 recordsLinked to original sources
PubMed1984

Prediction of pneumonia in outpatients with acute cough--a statistical approach.

Cough is the fifth most common reason for physician visits, but data on acute cough have rarely been collected in a standardized manner and have not been analyzed in a multivariate fashion. We report data on 1819 patients presenting with cough, all of whom received a standardized history and physical, and a chest X-ray. Only 48 (2.6%) were found to have an acute radiographic infiltrate (pneumonia). The prevalence of common signs and symptoms is shown for the patients with and without pneumonia. Thirty-two of these findings were significant predictors of pneumonia (p less than 0.05, one-tailed). These 32 did not include some of the expected predictors of pneumonia and did include some predictors not previously described in the literature. A diagnostic rule is developed which identifies pneumonia patients with 91% sensitivity and 40% specificity, or 74% sensitivity and 70% specificity. The study results suggest that many pneumonias could be predicted based only on the patients histories. Physician visits to determine physical findings and chest X-rays might be avoided by telephone triage, with substantial cost savings.

Acute Disease↗
PubMed1982

On the relationships among headache symptoms.

Headache classification has evolved through clinical experience because there are no objective findings which define causation or headache type. The resulting groupings are inconsistently defined, and may not be optimal for the study or treatment of headache patients. To determine whether the same headache types would have resulted if today's sophisticated statistical methods had been applied to standard data collected on unselected patients, 21 symptoms collected from 726 patients with acute headaches were analyzed. Five "natural' groupings or syndromes of symptoms were found in the data. Three were similar to traditional groupings: tension, migraine and cluster. Approximately one fourth of the patients had both tension and migraine symptoms, which suggests that the division of headaches into "tension' vs "migraine' has a large overlap. An "OCULAR' and a "URI' syndrome were also detected. Contrary to expectations, vascular headaches were not usually unilateral and patients with cluster headache symptoms were not usually males. The discrepancy between these findings and current perceptions may have been caused by differences in the populations or from biased patient selection in previous studies.

Cluster Headache↗
PubMed1982

Cluster analysis to determine headache types.

Cluster analysis was used to separate 726 headache patients into clusters of patients with similar symptoms. This was done to answer two questions: what "naturally occurring' groups of patients can be found? And how do these groups correspond to traditional headache types? When only two clusters were required, the best two clusters were tension and migraine-like. However, eight clusters could also be distinguished, and the migraine group then became very small. The clusters were tested for clinical interpretability by having 12 physicians name and prescribe treatment for the clusters. The suggested treatment was similar to what patients had actually received in about 2/3 of the cases but was rather different for the remainder. Further, the outcomes associated with different treatments appeared to vary by cluster. This suggests that the current method for classifying and treating headaches may not be optimal.

Adult↗