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Biomedical subjects

B Wongchaowart

Publications and source records attributed to B Wongchaowart.

2 recordsLinked to original sources

Case study: trauma-related hallucinations.

Proper differential diagnosis of psychiatric disorders with psychotic symptoms is imperative, as the treatment implications of the various conditions are quite different. A case study of a 5-year-old abused child with posttraumatic stress disorder is presented to illustrate some of the characteristic features of psychotic symptoms in traumatized children. Literature reviewed suggests that trauma-related hallucinations frequently contain content which is related to children's life experiences, are exacerbated by "triggers" and safety concerns, resolve with psychotherapy or psychosocial interventions, and are resistant to standard neuroleptic treatments. They are also associated with unique clinical, familial, developmental, and psychobiological correlates, and they require multifaceted treatment interventions.

Child↗

Respiratory failure in malignant histiocytosis.

A 29-yr-old man with a fever of several days duration developed rapidly progressive bilateral lung disease with respiratory failure. An open lung biopsy showed extensive acute lung injury with atypical cells, but was not diagnostic. Subsequent cervical lymph node biopsy was consistent with malignant histiocytosis. There was a brief response to chemotherapy, but respiratory failure progressed. He died 34 days after hospital admission. Autopsy revealed extensive neoplastic involvement of both lungs as well as the spleen, cervical, mediastinal, and upper abdominal lymph nodes. This is the first report, to our knowledge, of malignant histiocytosis presenting primarily in the lung and progressing rapidly to respiratory failure. The possibility that this represents a neoplasm of the pulmonary macrophages is discussed.

Adult↗