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Biomedical subjects

B Wuethrich

Publications and source records attributed to B Wuethrich.

16 recordsLinked to original sources
PubMed2000

Conservation biology. When protecting one species hurts another.

Biologists studying whether providing habitat for one wide-ranging species would protect another--the so-called umbrella effect--have found limited overlap between prime grizzly habitat and that of threatened fish, and grizzly conservation programs here may even be hurting the fish. Researchers are now grappling with how best to conserve habitat for multiple species.

Animals↗
PubMed2000

Conservation biology. Combined insults spell trouble for rainforests.

Scientists are now saying that a combination of interacting factors--including forest fragmentation, logging, and El Niño-driven drought--has altered the fire regimes of tropical forests and is changing regional climates and reconfiguring the landscape. These interactions are synergistic, they say--that is, the whole is greater than the sum of its parts. The concept provides a new paradigm for understanding the dynamics of fragmented rainforests and for approaching their conservation.

Borneo↗
PubMed1985

Immune response to Staphylococcus aureus in atopic dermatitis.

The skin of patients with atopic dermatitis (AD) is severely colonized with Staphylococcus aureus. Therefore, a study was conducted to assess some basic features of the S. aureus-specific immune response in patients with AD and healthy nonatopic individuals. Some particular features were found: a selective hyporesponsiveness to purified S. aureus cell walls (PCW) in delayed skin reactivity; half of our AD patients showed serum IgE to PCW and soluble S. aureus protoplast antigens; elevated PCW-IgE did not correlate with positive immediate skin reactions to whole S. aureus and their cell walls; regional lymphadenopathy but not impetiginization was associated with increased PCW-IgE and high total IgE. It is suggested that these changes in the immune response to S. aureus are related to the chronic S. aureus colonization of the skin.

Adolescent↗
PubMed1985

The immune response to S. aureus in atopic dermatitis.

The skin of patients with atopic dermatitis is heavily colonized with S. aureus, and their immune response to S. aureus shows some particular features: (1) A selective hyporesponsiveness to purified S. aureus cell walls in delayed type hypersensitivity skin reactions. (2) The presence of IgE to cell walls and soluble antigens of S. aureus in patients with high serum IgE levels. (3) Elevated cell wall IgE do not correlate with positive immediate skin reactions to whole S. aureus and their cell walls. (4) Regional lymphadenopathy but not impetiginization is associated with high total IgE and S. aureus cell wall IgE. We suggest that these changes in the immune response to S. aureus are related to the chronic S. aureus colonization of the skin.

Adult↗
PubMed1985

Staphylococcus aureus skin colonization in atopic dermatitis patients.

A study was conducted to compare the Staphylococcus aureus skin colonization of 21 patients with atopic dermatitis (AD) and 22 healthy controls. It was found that the total aerobe count (total CFU/cm2), the S. aureus fraction thereof and the S. aureus carrier frequency were significantly higher in apparently normal skin of AD patients than in healthy individuals. In addition, compared to normal skin of patients S. aureus density was 100 to 1,000 times higher in the 3 different kinds of lesional skin (dermatitic, lichenified and impetiginized sites). 190 S. aureus strains isolated from the skin of AD patients were tested for sensitivity to 5 topically used antibiotics and the results reported. Besides the biological consequences for the person affected by AD this severe colonization with S. aureus is of epidemiological importance. Several outbreaks of S. aureus infections by dispersal from dermatitic skin have been described. Therefore some preventive and therapeutic aspects are discussed.

Dermatitis, Atopic↗