Biomedical subjects

B Yáñez

Publications and source records attributed to B Yáñez.

3 recordsLinked to original sources

PubMed2004

[Ocular Behçet disease. Retrospective study].

OBJECTIVE: To study clinical features, visual prognosis and response to immunosuppressive drugs in patients with ocular Behçet Disease (BD). PATIENTS AND METHODS: clinical data of 17 patients (33 eyes) were retrospectively reviewed from May 1996 to May 2003. RESULTS: The male/female ratio was 12/5. The commonest manifestations were oral ulceration (100%) and skin lesions (88%). Anterior uveitis was present in 59%, posterior uveitis was in 76% and panuveitis was in 88.1%. Visual acuity improved in 11 (33.3%) eyes, remind stable in 18 (54.5%) eyes and four (12.1%) eyes lost two or more lines. Main drug therapy consisted of colchicine and cyclosporine (59%). Seven patients had received three drugs simultaneously. CONCLUSIONS: BD can lead to an irreversible visual loss; however, the visual prognosis is good (85%) if immunosuppressor treatment is implemented.

Adolescent↗

PubMed1983

[Use of Boyer's score in the differential diagnosis of meningitis].

Authors have studied reliability of Boyer's score for diagnosis of bacterial versus aseptic meningitis. This score is based upon clinical and biological data easily available in few hours since the patient's admission to hospital. They their have reviewed all cases of meningitis in hospital during the last four years. Boyer's score was very useful and its specificity (100%) and sensitivity (96,50%) were very high. Authors consider this test convenient and reliable for the presumptive diagnosis of the type of meningitis with its' therapeutic implications.

Bacterial Infections↗

PubMedDate not supplied

Experimental model of corneal haze in chickens.

PURPOSE: To develop an experimental animal model of corneal haze following photorefractive keratectomy (PRK). METHODS: Fifteen Iber Braun hens underwent unilateral PRK for -9.00 D of myopia. The animals were sacrificed at 1, 3, and 6 months postoperatively, and light microscopy was performed. RESULTS: Slit-lamp microscopy showed haze in the PRK-treated eyes. Histopathologic study disclosed epithelial hyperplasia, basement membrane abnormalities, and extensive anterior stromal disorganization. CONCLUSIONS: An easy and inexpensive model of haze after PRK was developed in an animal with Bowman's layer. This new model could be useful to understand the pathophysiology and pharmacologic modulation of corneal haze.

Animals↗