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Biomedical subjects

B Zöller

Publications and source records attributed to B Zöller.

61 records · Page 4Linked to original sources
PubMed1979

Hepatitis B virus markers among family contacts of asymptomatic HBsAg carriers.

A study was undertaken to establish the risk of family contacts of HBsAg carriers acquiring a hepatitis B virus (HBV) infection. About one-third of all household contacts of asymptomatic HBsAg carriers had signs of past or ongoing HBV infection. Family contacts of HBsAg carriers with high numbers of circulating Dane particles were shown to have a higher risk of developing HBV infection than family contacts of HBsAg carriers without serological evidence of HBV synthesis. The probability of acquiring HBV infection was not different between spouses, parents, children, and brothers and sisters, respectively of asymptomatic HBsAg carriers.

Adult↗
PubMedDate not supplied

[Interaction of isoxicam and digoxin].

The influence of maintenance therapy with Isoxicam, 200 mg daily, on digoxin steady-state plasma levels was studied on 12 healthy volunteers. One person dropped out from the investigation program on account of cardiac sensations following the invasion phase with digoxin. No statistically significant differences could be shown during concomitant therapy or after withdrawal of Isoxicam. Neither were toxic glycoside plasma concentrations observed. There were no pathological clinicochemical parameters, in particular no changes in renal function values.

Acetyldigoxins↗
PubMedDate not supplied

[Indomethacin kinetics in synovia and plasma following administration of indomethacin Gits 7/85 in patients with chronic polyarthritis].

Patients suffering from rheumatoid arthritis received a single dose of the new therapeutic system of indomethacin (Gits 7/85). Samples of plasma and synovial fluid were taken after 1, 2, 4, 6, 8, 10, 12, and 24 h. Concentration peaks could not be observed. After 2-3 h plasma levels were achieved which remained constant over the investigational period. Indomethacin concentrations in synovial fluid were seen with some delay. All synovial fluid levels after single application were lower than the plasma concentrations. The kinetics of elimination showed no difference between the two compartments. The above findings confirm the expectations regarding the new therapeutic system of indomethacin (Gits 7/85), i.e., the maintenance of a nearly constant plasma and synovia level for at least 10 h. The avoidance of peaks is seen as an additional advantage.

Arthritis, Rheumatoid↗