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Biomedical subjects

B Zdichynec

Publications and source records attributed to B Zdichynec.

At least 19 recordsLinked to original sources
PubMed1979

[Incidence and peculiar changes in the electrocardiogram of patients after cerebrovascular insults.--Epidemiological study of 70--105-year-old people (author's transl)].

An epidemicological study of 70 to 105-year-old people revealed a frequency of cerebrovascular insults from 1,8% of living and of 23,9 respectively 34,4% of deceased men or women. As typical changes of the electrocardiogram in recent insults are to be found prolongations of the QT-interval, large and often terminal negative T-waves as well as large and high, but over the left precordium often negative U-waves.

Age Factors↗
PubMed1978

Relative genealogic incidence of certain "civilization diseases" in a geriatric population versus pregeriatric groups.

In a prevalence epidemiologic study conducted in a characteristic submontane area in North Bohemia, the genealogic incidence of myocardial infarction, sudden brain vascular episodes, and malignant tumors was studied in a representative sample of persons aged 70 to 105 years. The incidence was then compared with that in two other samples: 1) men under age 40 with a history of transmural myocardial infarction, and 2) both men and women aged 40--60 who had a stroke. The statistical evaluation was performed according to accepted international criteria (WHO). A significantly lower genealogic incidence of myocardial infarction and sudden brain vascular episodes was found in the geriatric subjects (70--105 years old) who had symptoms of so-called physiologic aging, as compared with the incidence in the younger subjects who had symptoms of so-called pathologic aging. The difference was less clear-cut with respect to the genealogic incidence of malignant tumors.

Adult↗
PubMed1978

[Results of a comparing study concerning men under 40 years old and above 60 years, affected by myocardial infarction (author's transl)].

We examined a group of 300 men in the age of under 40 and a comparing group of 300 men in the age of 60 and more years, with clinically or histologically ascertained heart infarct (according to criterions of (WHO). Our work brought the proof that clinically unambiguous heart-infarct in the group of men under 40 years was always connected with the following main risk-factors: 1. hear-infarct of sudden death under 60 years in the family anamnesis. 2. increased hypercholesterinaemy (6.708 mol/1), hypertriglyceridenaemy (2.0g/1) and hyperuricaemy (416.5 u mol/1). 3. Increased smoking of cigarettes (a day 20 cigarettes). Time since the beginning of the attack until ringing up the physician was found out to be longer in the group of men more than 60 years old. Noteworthy is also the age-dependence of the time of out-living after myocard-infarct.

Adult↗
PubMed1978

Hypocholesterolemic effect of ascorbic acid in maturity-onset diabetes mellitus.

A significantly lower vitamin C concentration has been found in the blood and particularly in the leukocytes of hypercholesterolemic diabetic patients than of healthy blood donors. Ascorbic acid administered in a dose of 500 mg per day for 12 months to metabolically stabilized hypercholesterolemic subjects with maturity-onset diabetes mellitus (diabetic diet without insulin or diabetic drugs) brought about a striking decline of cholesterolemia and a moderate decline of triglyceridemia. The serum lipid level in the control group given placebo remained unaltered. A daily administration of 500 mg of ascorbic acid for six months failed to affect the fasting level of serum immunoreactive insulin. It is assumed that the long-term administration of ascorbic acid to maturity-onset diabetics removed the tissue ascorbate deficiency and improved the liver ability to compensate the increased endogenous synthesis of cholesterol by its enhanced transformation to bile acids.

Ascorbic Acid↗