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Biomedical subjects

B Zilberg

Publications and source records attributed to B Zilberg.

9 recordsLinked to original sources

A clinical and epidemiological study of gastro-enteritis.

Over a 13-year period, 2,903 Asian, Coloured and White children with gastro-enteritis were admitted to the Wilkins Infectious Diseases Hospital, Salisbury. During a pilot study of 250 patients conducted over the first 2 years, a definite seasonal variation in the occurrence of gastro-enteritis, with a peak incidence in winter, was noticed, and this led to a more detailed study of 2,653 patients over the next 11 years. Bacterial pathogens were recovered from 27% of patients, strains of Shigella accounting for 12% Salmonella for 7% and Escherichia coli for 8%. A severe outbreak of E. coli infection occurred between October 1971 and December 1972, and 4 of a total of 9 deaths occurred during this period, all in children suffering from E. coli 0111/B4 infections. The bacterial recovery rate was highest in the summer (40%) and lowest in the winter (12%). Winter diarrhoea broke out over 3-month periods during each year and accounted for 37% of the cases, but none of the children who contracted it died. The clinical picture of winter diarrhoea differed from the others and the most serious illness was that caused by enteropathogenic strains of E. coli. The over-all mortality in the series was 0,27%.

Child, Preschool↗

Virus particles and gastro-enteritis in Black and White Children in Rhodesia.

Stools from Black and White children with gastroenteritis and from controls were investigated for potentially pathogenic agents by conventional virological and bacteriological methods and by electron microscopy. Isolations were obtained in 30 percent of cases but electron microscopy more than doubled the number of agents found. Orbiviruses were present in 40 percent of all cases, often in combination with other organisms. There was no difference between the Black and White groups.

Black or African American↗