PubMed Health⌕ Search

Biomedical subjects

B Zur

Publications and source records attributed to B Zur.

4 recordsLinked to original sources

Autoimmune hepatitis in a genetically susceptible patient: is it triggered by acute viral hepatitis A?

The pathogenic mechanisms for autoimmune hepatitis (AIH) are not completely known. Susceptibility to AIH is associated with the human leukocyte antigens (HLA) class II: DR3 and DR4. Nevertheless, AIH does not have a strong genetic predisposition, suggesting that other factors are involved. Perhaps the strongest evidence of a viral cause for AIH exists for hepatitis C virus. AIH has been reported to develop rarely after acute infection with hepatitis A virus. We report on a 55-year-old woman in whom AIH developed during the convalescence period of serologically proven acute viral hepatitis type A. HLA class II DRB1*0401, which was reported to be associated with AIH with a moderate coarse and late appearance in life, was found in this patient. Steroid therapy was followed by a complete clinical remission. Our case supports the possibility that acute hepatitis A may trigger the development of AIH in a genetically susceptible subject.

Acute Disease↗

Comparative responses of lactating cows to total mixed rations or computerized individual concentrates feeding.

A trial was conducted in a commercial dairy herd in which the concentrate part of the ration was fed individually to a group of cows through computerized self-feeders. Performance results were compared with those of a group fed TMR of 65 to 67% concentrates. Rationing of individual concentrates was according to parity, milk yield, milk yield potential, BW changes, and bunk feed-stuffs. Mean intake of concentrates per cow was about 1 kg/d lower in the individually supplemented cows. This was partly compensated for by a higher intake of bunk feedstuffs. Overall daily milk yield per cow was similar to those receiving a TMR in first parity cows, higher in second parity cows, and lower in third and greater parity cows. The higher performance of the second parity cows was achieved in all milk yield potential classes, and the lower yield in subsequent lactations was due to lower performance in low and high potential classes. The individually supplemented cows gained less BW than those in the TMR group. Milk yield per unit of BW was better than milk yield as a variable to refine individual cow supplementation strategy for allocation of concentrates. Results also suggest that the same criteria used for supplementation of concentrates can be beneficial to cows' assignments and movements among different TMR groups. Computerized dispensing of concentrates, when applied properly, can economize on consumption of concentrates when grouping and feeding different TMR are impossible.

Animal Feed↗

Gelatin-based sprayable foam as a skin substitute.

Physical and antimicrobial properties of a newly developed gelatin based spray-on foam bandage for use on skin wounds have been evaluated. The aqueous foam is sprayed from aerosol containers and effectively covers and washes uneven wound surfaces. The foam dries to form an adherent and stable three-dimensional matrix which diminishes evaporative water losses. The foam possesses antimicrobial activity against gram-positive, gram-negative, and fungal contaminants.

Aerosols↗