PubMed Health⌕ Search

Biomedical subjects

B von Fischer

Publications and source records attributed to B von Fischer.

7 recordsLinked to original sources
PubMed1994

Kallmann syndrome and associated malformation of the uterus.

Kallmann syndrome is a rare combination of hypogonadotropic hypogonadism due to hypothalamic insufficiency and anosmia. In both patients treated at our institution for infertility, a malformation of the uterus was noted: one patient had a unicornuate uterus, the other a uterus with a fundal hypoplasia and tubes of approximately 9 cm. It is not clear if the malformation is in association with Kallmann syndrome or purely coincidental. Given the known association of other malformations with Kallmann syndrome, we suppose that probably an underlying genetic defect having to do with organogenesis is the cause of the uterine malformations.

Adult↗
PubMed1981

The rate of increase in urinary flow rate during micturition: a valuable urodynamic parameter for the diagnosis and differentiation of abnormalities of micturition in women.

The diagnostic significance of the maximum rate of increase in urinary flow during micturition, which is given by the tangent to the urinary flow curve at its point of maximum slope, was investigated at the University of Bern Women's Hospital. The micturition curves of 87 women were evaluated. Twenty four were in the control group, 36 had a variety of pathological conditions, and 27 had simple stress incontinence. For the measurement of urinary flow the bladder was filled until the subject felt the first need to micturate. The urinary stream was measured with an electronic balance (AMS flowmeter) and charted by a felt-pen recorder. In addition, continuous urethrocystotonometry was performed and urine was sampled for bacteriological examination. The results showed clearly that the maximum increase in urinary flow rate is of greater diagnostic value than the maximum and mean urinary flow or the micturition time. It is a simple, non-invasive method for differentiation between normal and pathological micturition curves. The discriminatory power of the test is age-independent. These investigations show that during the phase of active emptying of the bladder the rate of increase in urinary flow is the parameter which provides most diagnostic information.

Diagnosis, Differential↗
PubMed1980

Measurement of the transmission factor and stress factor at four points in the urethra in patients with stress incontinence.

The transmission factor and the stress factor (a new parameter introduced by us) were determined at points corresponding to 10%, 40%, 70%, and 90% of the functional length of the urethra in 25 women with stress-incontinence and were used to construct urethral closure pressure profiles. The measurements were made with the patients supine after infusion of 200 ml into the urinary bladder, and in the standing and supine positions following infusion of 300--400 ml. There was an almost linear decrease in the value of the transmission factor along the functional length of the urethra. In the distal third of the urethra we found significant differences in vesico-urethral pressure transmission between patients with differing degrees of stress incontinence. The significance of the transmission factor in the preoperative and postoperative evaluation of urethral closure pressure profiles is discussed.

Adult↗