Biomedical subjects
Publications and source records attributed to Banani Poddar.
The vast majority of children with heart murmurs have an 'innocent' murmur. Differentiation of such murmurs from those due to structural cardiac disease, so called 'pathological' murmurs, is largely clinical. Pediatricians are capable of differentiating one from the other, provided a detailed evaluation is done. This article outlines the salient features of innocent murmurs that help us recognize them clinically.
Bleeding diathesis is a cardinal feature of viperine bite, which has been thought to last not more than 24 hours. There is scarcity of literature about prolonged bleeding disorder in snake envenomation. Various explanations suggested in the literature include-temporary decrease in antivenin levels, rapid elimination of antivenin from circulation or continuous release of unneutralised venom from the envenomated site. Two children with prolonged coagulopathy lasting for more than a week, correction of which required more than 300 ml of antisnake venom are reported here.
Life threatening hypokalemia can be a mode of presentation in renal salt wasting (Group-1) patients of Bartter's syndrome causing hypokalemic respiratory paralysis. Treatment on an emergent basis is required. In the long run, such patients may require higher doses of supplementary potassium and potassium sparing diuretics.
Hyperekplexia is a rare clinical syndrome of pathologic startle response to unexpected stimuli such as sound or touch. The majority of cases are familial. Sporadic cases of hyperekplexia have also been reported, mostly in association with brainstem pathology. We describe a girl with sporadic hyperekplexia secondary to previously unreported cerebellar pathology. Her symptomatology was predominantly unilateral, being ipsilateral to the cerebellar involvement. This type of presentation, which may be termed hemihyperekplexia, has not been described before. Response to clonazepam was good but showed diurnal variations. The case is being reported for its unusual features.
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