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Biomedical subjects

Barbara Holmes Gobel

Publications and source records attributed to Barbara Holmes Gobel.

8 recordsLinked to original sources

Nursing-sensitive patient outcomes: the development of the Putting Evidence into Practice resources for nursing practice.

The Oncology Nursing Society (ONS) has worked diligently to improve the care of patients with cancer and their families. A recent project that demonstrates this commitment toquality care is the development of nursing-sensitive patient outcomes resources. ONS has teamed researchers, advanced practice nurses, and staff nurses to develop Putting Evidence Into Practice resources that provide guidance for nursing interventions based on the evidence. The ability to provide evidence for nursing interventions is critical to all aspects of patient care, including patient teaching, development of patient care policies and procedures, and provision of direct patient care.

Evidence-Based Medicine↗

Putting evidence into practice: prevention of infection.

The prevention of infection is an important outcome to measure in patients with cancer because infectious complications are a significant cause of morbidity and mortality. Nurses play a vital role in the prevention of infection in patients with cancer through nursing practice, research, and patient education. However, many common nursing interventions to prevent infection are based on tradition or expert opinion and have not been subjected to scientific examination. The 2005 Oncology Nursing Society Prevention of Infection Outcomes Intervention Project Team reviewed, critiqued, and summarized the research evidence for nursing interventions to prevent infections in patients with cancer. Pharmacologic and nonpharmacologic interventions were included because many advanced practice nurses prescribe medications. This article is an evidence-based review of nursing interventions to prevent infection in patients with cancer.

Antibiotic Prophylaxis↗

Chemotherapy-induced hypersensitivity reactions.

PURPOSE/OBJECTIVES: To assist clinical nurses in understanding the complex nature of chemotherapy-induced hypersensitivity reactions as well as effectively preventing or managing these reactions. DATA SOURCES: Published articles and abstracts, pertinent book chapters, computerized databases. DATA SYNTHESIS: Most available chemotherapy drugs can cause hypersensitivity reactions, but certain drug groups frequently are associated with these reactions (e.g., asparaginases, taxanes, platinum compounds, epipodophyllotoxins). Preventing hypersensitivity reactions is the primary goal; however, understanding the principles of managing these reactions is critical because hypersensitivity reactions can occur despite using appropriate prevention strategies. CONCLUSIONS: Chemotherapy-induced hypersensitivity reactions are potentially life-threatening. Nurses working with chemotherapy drugs must understand which drugs are associated with a high risk of causing hypersensitivity reactions and must be prepared to attempt to prevent or manage reactions. IMPLICATIONS FOR NURSING: The potentially life-threatening nature of hypersensitivity reactions to chemotherapy requires that nurses have a plan to manage them. This may include a written policy on staff education and training, appropriate equipment, and medications.

Antineoplastic Agents↗

Management of tumor lysis syndrome: prevention and treatment.

OBJECTIVES: To provide a review of the preventive and treatment strategies for tumor lysis syndrome (TLS). DATA SOURCES: Primary and tertiary literature and clinical experience. CONCLUSIONS: The oncology nurse can optimize outcomes in the patient at risk for TLS through a variety of prevention and treatment interventions: (1) aggressive patient monitoring for early identification and treatment; (2) minimize risk factors via thorough medication and nutritional histories, and assurance of proper prophylactic regimens; (3) assessment of optimal routes of drug delivery to assure medication bioavailability; and (4) reinforcement of the above with comprehensive patient education. IMPLICATIONS FOR NURSING PRACTICE: Awareness and effective use of prophylactic and treatment regimens related to TLS will positively impact patient outcomes. The oncology nurse is at the front line to identify issues related to effective management of TLS.

Adult↗

Use of the Pleurx Pleural Catheter for the management of malignant pleural effusions.

Many patients with cancer, especially those with lung and breast cancer, experience malignant pleural effusions. Several treatment options exist, and most require hospitalization. The Pleurx Pleural Catheter (Denver Biomedical, Golden, CO) is a new treatment option that allows patients to be treated on an outpatient basis for weeks or months. With a catheter in place, pleural effusions can be drained intermittently at home by trained family members or caregivers. Nurses play a critical role in educating patients about the use of the Pleurx catheter, as well as teaching patients and family members how to drain the catheter. The purpose of this article is to familiarize nurses with the proper care of Pleurx catheters and provide a basis for patient education.

Catheterization↗