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Biomedical subjects

Barton F Branstetter

Publications and source records attributed to Barton F Branstetter.

At least 19 recordsLinked to original sources

'Wet Reads' in the age of PACS: technical and workflow considerations for a preliminary report system.

Communication between clinicians, technologists, and radiologists has become more complex, with Picture Archiving and Communication Systems (PACS) now allowing the radiologist to be removed from the physical location of the patients and the site of imaging. With these changes, effective communication becomes an ongoing challenge. Efficient communication of study interpretations has also become a priority for radiologists as they struggle to maintain relevance and provide added value to patient care when clinicians have ready access to radiology images. The purpose of this paper is to share our experience in developing and implementing the Collaborative Notification System (CNS), a communication tool used to inform referring clinicians of urgent findings-a.k.a. "wet reads." The system utilizes a system of web pages integrated into PACS for the sending and receiving of succinct messages to provide clinical information at the point of need. A second system of pager alerts provides notification of the need for such communication through a relatively unintrusive, one-way, acknowledged alert system. The CNS provides asynchronous, integrated communication for the reporting of urgent and emergent radiology findings in a complex, geographically distributed medical environment.

Efficiency, Organizational↗

Preclinical medical student training in radiology: the effect of early exposure.

OBJECTIVE: The purpose of this study was to determine whether an integrated radiology curriculum in the first year of medical school changes medical students' attitudes toward radiology or affects their knowledge of radiologic principles. SUBJECTS AND METHODS: The first-year medical curriculum of a medical school was revised between the 2003 and 2004 academic years to introduce more didactic radiology teaching. Dedicated radiology lectures were introduced, and radiology consult sessions became integral to problem-based learning sessions. A survey was administered between the first and second years of training to assess first-year medical students' attitudes toward radiology and their knowledge of basic radiologic principles. Students who had undertaken the revised curriculum (class of 2008) were compared with students who had undertaken the traditional curriculum (class of 2007). Survey responses were compared with Mann-Whitney rank sum tests. RESULTS: Students exposed to the new curriculum stated that they were more familiar with radiology as a specialty and believed that radiology had greater importance to the overall practice of medicine. They stated that they were more likely to select radiology as a clinical elective, and more of them were considering radiology as a career option. The students who had been exposed to radiology performed better on the test of basic radiologic knowledge. All results were statistically significant. CONCLUSION: Exposing students to radiology in the first year of medical school improves their impression of radiology as a specialty and increases their interest in radiology as a career. Follow-up surveys will determine whether this effect persists through the clinical years of training and improves the overall impression of radiology within the medical community.

Attitude of Health Personnel↗

Posttreatment assessment of response using FDG-PET/CT for patients treated with definitive radiation therapy for head and neck cancers.

PURPOSE: The goal of this study was to evaluate coregistered [18F] fluorodeoxyglucose (FDG)-positron emission tomography (PET)/computed tomography (CT) for the detection of persistent disease after definitive radiation therapy in head and neck cancer. METHODS AND MATERIALS: Posttreatment FDG-PET/CT was performed in 28 patients on average 8 weeks (range, 4 to 15.7 weeks) after completing definitive radiation therapy. FDG-PET/CT was visually analyzed for the entire patient group and at two time points (4-8 and >8 weeks) after treatment. The contrast-enhanced CT portion of PET/CT was separately analyzed blinded to the results of coregistered FDG-PET/CT and classified as negative or positive for residual locoregional disease. Pathologic findings and clinical follow-up served as the reference standard. RESULTS: Follow-up data were available for all 28 patients (median, 17.6 months). Regarding the detection of residual disease, the overall sensitivity and specificity of FDG-PET/CT was 76.9% and 93.3%, respectively, compared with 92.3% and 46.7% for contrast-enhanced CT. The accuracy of FDG-PET/CT was 85.7%, compared with 67.9% for CT alone. All false-negative (n = 3) and false-positive (n = 1) FDG-PET/CT results occurred between 4 and 8 weeks after treatment. At 8 weeks or later after treatment, the specificity of CT was 28%, compared with 100% for FDG-PET/CT. CONCLUSIONS: The metabolic-anatomic information from coregistered FDG-PET/CT provided the most accurate assessment for treatment response when performed later than 8 weeks after the conclusion of radiation therapy. FDG-PET/CT excelled by a higher specificity and overall diagnostic performance than CT imaging alone. These results support a potential clinical role of FDG-PET/CT in the early assessment of therapy response after definitive radiation therapy.

Adult↗

The radiologic evaluation of tinnitus.

Tinnitus ("ringing in the ears") is a prevalent symptom in the general population, and often brings patients to medical attention. Many causes of tinnitus are evident radiographically. The most frequently-encountered causes of tinnitus are discussed, and imaging recommendations are provided.

Contrast Media↗

Superior semicircular canal dehiscence: oblique reformatted CT images for diagnosis.

PURPOSE: To retrospectively determine, by using thin-section multi-detector row computed tomography (CT), whether additional reformations in the planes of Stenver and Pöschl change the diagnostic interpretation for superior semicircular canal dehiscence (SSCD) when compared with the diagnostic interpretation of standard coronal reformations for SSCD. MATERIALS AND METHODS: Institutional review board approval was obtained, patient anonymity was maintained, and the study was HIPAA compliant. Twenty-seven patients (17 men, 10 women; average age, 45 years; range, 19-72 years) suspected of having SSCD who underwent temporal bone multi-detector row CT were retrospectively identified from electronic medical records. An additional 27 control subjects (nine men, 18 women; average age, 50 years; range, 18-87 years), who underwent temporal bone multi-detector row CT for other reasons, were retrospectively selected from the same period. Two neuroradiologists with certificates of added qualification, one with 5 years and one with 9 years of experience interpreting temporal bone CT images, independently reviewed the 108 temporal bones twice. One review was restricted to transverse images and coronal reformations. The other review used transverse images, coronal reformations, and oblique reformations in the planes of Stenver and Pöschl. The observers were blinded to clinical history, and the two reviews took place 3 months apart to avoid recall bias. The primary outcome measure was the intraobserver discordance rate between the two reviews. kappa Statistics were used to evaluate both intraobserver and interobserver variability. RESULTS: Observer 1 diagnosed SSCD in 25 of 108 (23%) temporal bones and had no discordances between the two reviews. Observer 2 diagnosed SSCD in 21 of 108 (19%) temporal bones and had one intraobserver discordance. After a post hoc consensus review of this one discordance, the radiologic diagnosis remained equivocal. The discordance involved the right temporal bone of a patient suspected of having SSCD in the left temporal bone, so no clinical follow-up was available. CONCLUSION: Coronal reformations from multi-detector row CT of the temporal bone are sufficient for the evaluation of SSCD. Additional reformations in the planes of Stenver and Pöschl do not change the radiologic diagnosis and may be reserved for equivocal or confusing cases.

Adolescent↗

Flying blind: using a digital dashboard to navigate a complex PACS environment.

Radiology workflows have become more distributed and complicated, and fewer tangible cues are available to the radiologist to help optimize task prioritization and selection. Additionally, faster scanners, more detailed exams, and increased demand for imaging services have precipitated a potential image overload for today's radiologists who are pressured to provide efficient, quality service in less time. Radiologists are faced with the task of operating within complex systems but are lacking tools to efficiently and effectively monitor these systems in real time. Dashboard technology can help address this deficiency in radiology and facilitate informed, optimized decisions about workflow. Possible areas of application include workflow consolidation, workload distribution, and urgency evaluation. Dashboards should be optimized, context-sensitive, customizable, and workflow-integrated. Further research is needed to identify the most important dashboard metrics, determine their optimal display, and validate their utility.

Data Display↗

Normal CT appearance of the distal thoracic duct.

OBJECTIVE: The aims of this study were to determine how often the distal thoracic duct can be identified on neck CT and to characterize the CT appearance of the duct. MATERIALS AND METHODS: In a review of electronic medical records from January 2001 to January 2003 we identified the cases of 500 patients who had undergone CT of the neck. Because they had confounding factors such as cancer or cervical lymphadenopathy, 199 of these patients were excluded, leaving 301 patients in the study: 131 (44%) male patients and 170 (56%) female patients. The age range was 11-92 years (average age, 46 years). Two head and neck radiologists used strict diagnostic criteria and consensus to identify the distal thoracic duct on both sides of the neck. One half of the images selected at random were flipped left to right. The purpose of randomization was to avoid interpretation bias, because the thoracic duct is known to typically course within the left side of the neck. The configuration of the distal duct was tabulated, and effects of age and sex were statistically evaluated. RESULTS: The left side of the neck was unevaluable in 26 (9%) of 301 patients because of streak artifact. In the other 275 patients, the distal thoracic duct was identified in the left side of the necks of 150 (55%) of the patients. Eleven of these patients (4%) also had a visible duct in the right side of the neck, but a right-sided duct was never identified without a left-sided counterpart. The distal thoracic duct had a tubular configuration in 70 (43%), a flared configuration in 72 (45%), and a long segmental fusiform dilation in 19 (12%) of 161 patients. Patient sex had no significant effect on the appearance of the distal thoracic duct. Older patient age had a slight positive effect on the size of the duct. CONCLUSION: Familiarity with the normal CT appearance of the distal thoracic duct can be helpful in differentiating a normal duct from pathologic lesions of the lower neck, such as lymphadenopathy.

Adolescent↗

Diagnostic utility of positron emission tomography-computed tomography for predicting malignancy in cystic neck masses in adults.

OBJECTIVES: Combined positron emission tomography and computed tomography (PET-CT) is used for the diagnostic evaluation and staging of squamous cell carcinoma of the head and neck (SCCHN). By superimposing anatomic localization of CT with the physiologic data of PET, occult primary and metastatic neoplasms might be identified. Because the diagnostic algorithm for cystic neck masses in adults often overlaps with the work-up of cancer of unknown primary site, we evaluated the utility of PET-CT scans to identify the presence of malignancy and the location of primary tumor. STUDY DESIGN: Single-institution retrospective case review series. METHODS: We reviewed the PET-CT imaging of cystic neck masses occurring in five patients over 40 years of age with significant risk factors for SCCHN and correlated this information with histopathology. RESULTS: In each patient in our series, the PET portion of a combined PET-CT was misleading, whereas the CT examination was more suggestive of the correct pathology. Ultimately, clinical judgment and endoscopic evaluation, guided by CT findings, were most valuable for distinguishing malignant versus benign processes and identifying the primary tumor sites. CONCLUSIONS: PET-CT may not be a reliable modality for identifying malignancy in adults with suspicious cystic neck masses. A thorough clinical evaluation by an experienced head and neck surgeon, in conjunction with contrast-enhanced CT, may be sufficient to facilitate the optimal management of such patients.

Adult↗

Current use of 18F-fluorodeoxyglucose positron emission tomography and combined positron emission tomography and computed tomography in squamous cell carcinoma of the head and neck.

The history and physical examination, computed tomography (CT) and magnetic resonance imaging are the cornerstones for identifying new and recurrent cancers of the head and neck. The advent of positron emission tomography (PET) and combined PET/CT imaging technology is a promising development. These modalities have the potential to help stage patients presenting with head and neck cancer, identify responses to nonsurgical therapy, and allow earlier detection of recurrence in the hope of improving survival. The following paper provides a brief history of PET and PET/CT imaging. The current PET and PET/CT literature for squamous cell carcinoma of the head and neck is reviewed, and specific recommendations for its use are provided.

Carcinoma, Squamous Cell↗

Head and neck malignancy: is PET/CT more accurate than PET or CT alone?

PURPOSE: To prospectively determine whether combined positron emission tomography (PET) and computed tomography (CT) is more accurate than either PET or CT alone in depicting malignant lesions in the head and neck. MATERIALS AND METHODS: Study was approved by the institutional review board, and patient informed consent was waived. Sixty-five consecutive patients (42 men, 23 women; age range, 43-83 years) known to have or suspected of having head and neck cancer were examined with combined PET/CT. CT was performed with intravenous administration of a contrast agent, and the CT data were used for attenuation correction. Each examination was interpreted in three ways: PET images in the absence of CT data, CT images in the absence of PET data, and fused PET/CT images. Probability of malignancy of each lesion was assigned a score by using a five-point scale. Receiver operating characteristic (ROC) analyses were performed by using biopsy, imaging, or clinical follow-up as the reference standard. The minimum follow-up was 6 months (range, 6-12 months). The results were additionally analyzed to assess the degree of radiologist confidence. RESULTS: Follow-up was available for 64 (98%) of 65 patients. ROC analyses demonstrated that PET/CT is significantly superior to PET or CT alone for depiction of malignancy in the head and neck (P < .05). In this series, PET/CT had a sensitivity of 98%, a specificity of 92%, and an accuracy of 94%. Radiologist confidence was substantially higher with the combined modality. CONCLUSION: Combined PET/CT is more accurate than PET or CT alone for the depiction of malignancy in the head and neck. Radiologist confidence is improved with the combined modality.

Adult↗

Teflon granuloma in the nasopharynx: a potentially false-positive PET/CT finding.

Positron emission tomography (PET) has become a critical diagnostic tool in the discovery and staging of malignancies in the head and neck. Although PET is accurate for detecting cancer, increased 18 F-fluorodeoxyglucose (FDG) uptake can be seen in healthy tissues such as muscle, fat, and glands and uptake can be seen in tissues affected by inflammation or granulomatous disease. Combined PET and CT (PET/CT) can often overcome these difficulties by fusing anatomic and physiological data, but radiographic findings of some disease processes can be confusing even with fused imaging techniques. We present two cases of FDG uptake in the posterior pharynx, localized by combined PET/CT, which was initially interpreted as squamous cell carcinoma. The increased activity was ultimately attributed to Teflon-induced granulomas. It is important for radiologists to recognize potential causes of false-positive PET/CT findings to improve our diagnostic accuracy and to avoid unnecessary biopsies and surgeries.

Aged↗

Cricoarytenoid rheumatoid arthritis: an important consideration in aggressive lesions of the larynx.

The most frequent cause of an aggressive mass in the larynx is squamous cell carcinoma (SCC). Rheumatoid arthritis is known to affect the larynx but does not usually produce an aggressive mass. We present a case of rheumatoid arthritis in a 63-year-old woman who presented with acute upper airway obstruction. On CT scans, an erosive mass on the right cricoid cartilage with significant destruction of the surrounding structures was presumed to be an aggressive SCC. Surgical biopsies revealed rheumatoid arthritis of the cricoarytenoid joint. When a patient with rheumatoid arthritis presents with a mass in the larynx, cricoarytenoid rheumatoid arthritis should be ruled out even in the face of an aggressive lesion appearance at CT.

Arthritis, Rheumatoid↗

Uncommon CT findings in relapsing polychondritis.

Relapsing polychondritis is a rare inflammatory disorder of cartilage with well-established clinical features and imaging characteristics. Abnormal calcification and erosion of cartilaginous structures are the traditional radiographic findings. As with any disease, aberrancies of the expected clinical presentation may lead to a delayed (or missed) diagnosis. We discuss a rare case of relapsing polychondritis in which the diagnosis was suggested on the basis of CT findings, despite uncharacteristic clinical and radiographic manifestations of the disease.

Adult↗