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Biomedical subjects
Beau B Bruce
Publications and source records attributed to Beau B Bruce.
Ophthalmoparesis in idiopathic intracranial hypertension.
PURPOSE: To report unusual ocular motility disturbances in the setting of idiopathic intracranial hypertension (IIH). DESIGN: Interventional case series. METHODS: Two cases with IIH and unusual ophthalmopareses are reported. RESULTS: Two patients with confirmed IIH presented with headache, diplopia, and papilledema. The first patient had bilateral sixth nerve palsies and a partial right third nerve palsy, which resolved rapidly after a cerebro spinal fluid (CSF) shunting procedure; the second patient had alternating skew deviation and upbeat nystagmus. Both cases had normal brain magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) and normal CSF contents, ruling out a secondary cause of intracranial hypertension. CONCLUSIONS: These exceptional vertical and horizontal ophthalmopareses in the setting of IIH may be related directly to very elevated CSF pressures and may be secondary to altered CSF flow in the posterior fossa.
Adult↗
Ischemic stroke after electroconvulsive therapy.
Stroke is an exceptionally rare complication of electroconvulsive therapy since modern anesthesia and appropriate medical screening were instituted in the 1950s. Postictal focal neurological deficits mimicking stroke are common, but the advent of acute stroke therapies has made the differentiation of these from true cerebrovascular events critical. We present the first case report of ischemic stroke after electroconvulsive therapy with radiographic confirmation.
Adult↗
Aphasia and thalamotomy: important issues.
Patients may present with classical symptoms suggesting aphasia following thalamotomy (repetition, comprehension, fluency and naming abnormalities). They may also present with 'freezing of speech', and this symptom should not be considered as a speech disorder or a symptom of Parkinson's disease progression, without careful testing to rule out language deficits, particularly dysfluency. There are important issues related to all language complications of thalamotomy, including (1) the time course of problems following surgery, (2) the impact of preexistingspeech problems, (3) the importance of the size and location of lesions, (4) the potential circuits important in the pathogenesis of a thalamic language disturbance and (5) whether laterality makes a difference (left- versus right-sided thalamic lesions). As more centers switch from thalamotomy to deep brain stimulation, the issues regarding aphasia will need to be addressed.
Aphasia↗