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Benedetta Boari

Publications and source records attributed to Benedetta Boari.

36 records · Page 2Linked to original sources
PubMed2004

Influence of circadian rhythm on mortality after myocardial infarction: data from a prospective cohort of emergency calls.

Myocardial infarction (MI) occurs more frequently in the morning as a result of the concomitant unfavorable timing of several physiological parameters and/or biochemical conditions. However, little is known about the possible influence of this circadian pattern on prognosis. To evaluate whether the time of symptom onset could potentially influence mortality from acute MI, this prospective study considered all consecutive MIs admitted to the ED of Ferrara, Italy, after a call to the Emergency Coordinating Unit from January 1, 1998, to December 31, 2001. The total sample consisted of 442 MIs (mean age, 68.7 years; males, 72%). Eighty patients (males, 82.5%) died in the ED; the remaining 362 were admitted to the hospital. Of these, 50 (males, 60%) died during their hospital stay. Based on the timing of their symptom onset, cases were categorized both into 24 1-hour intervals and four 6-hour intervals (midnight to 5:59 am, 6:00 am to 11:59 am, noon to 5:59 pm, and 6:00 pm to 11:59 pm), and the circadian distributions of fatal versus nonfatal MIs were compared. The circadian variation of MI peaked between 6:00 am and noon (P < .001), and in this period, there was a trend toward a higher frequency of fatal cases (41.5% vs. 35.2%; chi(2) = 1.911, P = .167). To verify whether this higher frequency of fatal events in the morning hours could be related to possible higher severity of cases observed in that hours, a further separate analysis considering age, infarct site, and peak levels of MB was made. Again, no significant temporal differences among the four 6-hour intervals were found between fatal and nonfatal Mis, although a trend toward older age was observed in morning MIs. Not only the frequency, but also the mortality, of acute MI could be increased in the morning hours. This could be of practical interest for emergency doctors and could have significant implications for acute treatment, because several studies have reported a lowered efficacy of thrombolytic drugs in the morning hours.

Age Factors↗
PubMed2004

Circadian and seasonal variation of first febrile seizures.

Time of occurrence of 188 first febrile seizures (FS) was recorded, both by four 6-hour periods and by hourly intervals. The frequency of events was significantly ( P < .001) increased from 6 to 11.59 pm with a peak between 5 and 8 pm . A seasonal peak was observed in January.

Body Temperature↗
PubMed2004

Thromboangiitis obliterans (Buerger disease) in a female mild smoker treated with spinal cord stimulation.

The authors report the case of a 42-year-old female mild smoker admitted to the Hospital of Ferrara for the onset of asymptomatic necrotic ulcerations localized to the second, third, and fourth toes of left foot. Physical examination showed asphygmia of inferior limb distal peripheral pulses, with localized extremity marbleized and cyanotic skin at the level of the left foot, where necrotic ulcers were present at the second, third, and fourth toes. Doppler ultrasonography and angiography revealed a severe obliterating arteriopathy of bilateral distal arterial circulation. Both blood chemistry panel (including autoimmune and hypercoagulable profile) and diagnostic examination findings were normal. Thus, the patient met several criteria to be diagnosed with Buerger disease. After an attempt at medical therapy with the intravenous administration of the prostaglandin-analogue iloprost, given the young age and the lack of viable distal target vessels for bypass grafting, a spinal cord stimulator was implanted. More than 2 years later, the patient has a normal life.

Adult↗
PubMed2003

Penile trauma.

Explore the source record for details and available documents.

Adolescent↗
PubMed2003

[Circadian rhythm and renal colic].

Many physiological variables show a temporal pattern characterized by rhythmic changes along a time period, e.g. a day, a week, a month, a year, and it is also known that several acute diseases show a rhythmic variability as well. In these last years, high risk periods have been so identified, probably secondary to the temporal overlapping of favouring or triggering mechanisms. Recently, a circadian variability has been reported also for the occurrence of renal colic, with a pattern characterized by a morning peak, independent of gender and presence or not of demonstrable kidney stones. Most, if not all, renal functions exhibit temporal changes e.g. glomerular filtration rate, urine production and renal excretion of solutes, leading to an increased night-time concentration of urine, which could act as a predisposing factor for the morning occurrence of renal colic attacks.

Circadian Rhythm↗
PubMed2002

Circadian pattern of emergency calls: implications for ED organization.

A circadian variation has been shown in the onset of acute medical diseases and we postulate that there is a circadian variation in emergency calls. We reviewed the 20,858 emergency calls addressed to the Emergency Coordinating Unit of the Hospital of Ferrara, Italy, from January 1 to December 31, 1998. Precise determination of the time of calls was available from the recordings. Total calls and subgroups by different diseases were categorized into 24 one-hour increments and analyzed for circadian rhythmicity by applying a partial Fourier series. A circadian variation was found for all subgroups, except for alcoholic intoxication. There was a peak frequency of calls in the morning hours for cardiologic, respiratory, and neurologic disease. There was a peak frequency of calls in the afternoon for trauma, neoplastic diseases, and acute poisoning. Organization of quantity and quality of Emergency Department (ED) staff should take into account the increased demand of specific facilities during certain hours of the day.

Circadian Rhythm↗
PubMed2002

Morning preference in onset of symptomatic third-degree atrioventricular heart block.

The aim of this study was to examine 24h patterning in the symptoms indicative of third-degree atrio-ventricular (AV) heart block. We found a total of 227 cases (126 men and 101 women) of third-degree AV block that had been diagnosed by the Emergency Medical Department of the St. Anna Hospital in Ferrara, Italy between 1990 and 2001. Determination of the hour of onset of symptomatic third-degree AV block, however, was possible and listed in the records of only 161 or 70.9% of the cases (92 men and 69 women). The onset time of every event was categorized into one of four 6h spans of the 24h: night (00:00-05:59h), morning (06:00-11:59h), afternoon (12:00-17:59h), and evening (18:00-23:59h). The onset of the symptoms of third-degree AV block in the sample of 161 cases was significantly greater in the morning between 06:00 and 11:59h than any other 6h span of the day and night (chi2-test; p < 0.001). The same phenomenon was substantiated in the subgroup of the 92 males (chi2; p < 0.0001), although it could not be detected for the smaller subgroup of 69 women. The 24h pattern, with morning preference, in the onset of symptomatic third-degree AV block is similar to the one in sudden cardiac death and cardiogenic cardiac arrest. The etiology of the 24h pattern in symptomatic AV block is unknown; it may be an expression of intrinsic biological rhythmicity within the heart tissue or its control system, and/or the timing of environmental triggers resulting in coronary ischemia.

Aged↗
PubMedDate not supplied

Circadian and seasonal variation of migraine attacks in children.

OBJECT: To investigate the rhythmicity of migraine episodes without aura in a pediatric population. METHODS: Time of occurrence of 2517 migraine attacks in 115 children was recorded, by means of a diary, both by hourly and monthly intervals. RESULTS: A significant circadian variation, characterized by a peak in the afternoon (P < .001) and one in the early morning (P= .002) was found. A seasonal peak was also observed between November and January, while a nadir was observed in July. CONCLUSIONS: The clustering of attacks in the morning and midday and in autumn-winter, with a minimum frequency in July, suggests that school activities may represent an important cause of migraine.

Adolescent↗