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Biomedical subjects

Benjamin C Lopez

Publications and source records attributed to Benjamin C Lopez.

8 recordsLinked to original sources

Trigeminal neuralgia.

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Analgesics, Non-Narcotic↗

Patient reports of satisfaction after microvascular decompression and partial sensory rhizotomy for trigeminal neuralgia.

OBJECTIVE: There are no reports of patient satisfaction surveys after either a microvascular decompression (MVD) or a partial sensory rhizotomy (PSR) for trigeminal neuralgia. This study compares patient satisfaction after these two types of posterior fossa surgery for trigeminal neuralgia, because it is postulated that recurrences, complications, and previous surgical experience reduce satisfaction. METHODS: All patients who had undergone their first posterior fossa surgery at one center were sent a self-complete questionnaire by an independent physician. Among the 44 questions on four standardized questionnaires were 5 questions that related to patient satisfaction and experience of obtaining care. Patients were divided into those having their first surgical procedure (primary) and those who had had previous ablative surgery (nonprimary). RESULTS: Response rates were 90% (220 of 245) of MVD and 88% (53 of 60) of PSR patients. Groups were comparable with respect to age, sex, duration of symptoms, mean duration of follow-up, and recurrence rates. Overall satisfaction with their current situation was 89% in MVD and 72% in PSR patients. Unsatisfied with the outcome were 4% of MVD and 20% of PSR patients, and this is a significant difference (P < 0.01). Satisfaction with outcome was higher in those undergoing this as a primary procedure. In the primary group, satisfaction was dependent on recurrence and complication/side effects status (each P < 0.01), but this was not the case in the nonprimary group. Patients expressed a desire for earlier posterior fossa surgery in 73% of MVD and 58% of PSR patients, and this was highest in the primary group. The final outcome was considered to be better than expected in 80% of MVD and 54% of PSR patients, but 22% of the PSR group (P < 0.01) thought they were worse off. CONCLUSION: Patients undergoing posterior fossa surgery as a primary procedure are most satisfied and PSR patients are least satisfied, partly because of a higher rate of side effects.

Decompression, Surgical↗

Trigeminal neuralgia.

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Analgesics, Non-Narcotic↗

Systematic review of ablative neurosurgical techniques for the treatment of trigeminal neuralgia.

OBJECTIVE: There are no randomized controlled trials comparing retrogasserian percutaneous radiofrequency thermocoagulation, glycerol rhizolysis, balloon compression of the gasserian ganglion, and stereotactic radiosurgery, nor are there systematic reviews using predefined quality criteria. The objective of this study was to systematically identify all of the studies reporting outcomes and complications of ablative techniques for treatment of trigeminal neuralgia, from the development of electronic databases, and to evaluate them with predefined quality criteria. METHODS: Inclusion criteria for the outcome analysis included thorough demographic documentation, defined diagnostic and outcome criteria, a minimum of 30 patients treated and median/mean follow-up times of 12 months, not more than 20% of patients lost to follow-up monitoring, Kaplan-Meier actuarial analysis of individual procedures, less than 10% of patients retreated because of failure or early recurrence, and a minimal dose of 70 Gy for stereotactic radiosurgery. High-quality studies with no actuarial analysis were used for the evaluation of complications. RESULTS: Of 175 studies identified, 9 could be used to evaluate rates of complete pain relief on a yearly basis and 22 could be used to evaluate complications. In mixed series, radiofrequency thermocoagulation offered higher rates of complete pain relief, compared with glycerol rhizolysis and stereotactic radiosurgery, although it demonstrated the greatest number of complications. CONCLUSION: Radiofrequency thermocoagulation offers the highest rates of complete pain relief, although further data on balloon microcompression are required. It is essential that uniform outcome measures and actuarial methods be universally adopted for the reporting of surgical results. Randomized controlled trials are required to reliably evaluate new surgical techniques.

Clinical Trials as Topic↗

Trigeminal neuralgia.

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Analgesics, Non-Narcotic↗

Quality of reporting in evaluations of surgical treatment of trigeminal neuralgia: recommendations for future reports.

OBJECTIVE: There are numerous reports on the surgical treatment of trigeminal neuralgia, but the studies do not use uniform outcome measures, which makes it difficult for patients and clinicians to determine which treatment may be most appropriate. The objectives of this study were to set quality criteria and standards for outcome reporting for the surgical treatment of trigeminal neuralgia (on the basis of international expert opinion), to identify and assess all studies of the surgical treatment of trigeminal neuralgia and evaluate the studies against those criteria, and to provide recommendations for submitting reports on the outcomes of surgical treatment of trigeminal neuralgia. METHODS: The types of data that 11 neurosurgeons and 2 neurologists considered essential for articles reporting the outcomes of surgical treatment of trigeminal neuralgia were the quality criteria used by the two authors. Standards were established in terms of the minimal number and type of criteria that studies should meet to allow their use in a potential systematic review of pain outcomes of surgical treatment of trigeminal neuralgia. Studies were identified in MEDLINE searches and from other sources and were independently scored against those criteria by the two authors. The reproducibility of the method was checked with assessments of inter- and intra-rater reliability. A checklist for the reporting of studies was formulated. RESULTS: A total of 281 studies were identified, of which 222 were scored. Seventy-one (32%) of the studies reached the minimal set standards, but only 28 (13%) could be used for assessment of pain outcomes, because they included actuarial analyses. There was good agreement between the two authors in the scoring of the studies, although some criteria required stricter definitions. A checklist for the reporting of future studies on the surgical treatment of trigeminal neuralgia was proposed. CONCLUSION: When assessed against the proposed criteria and standards, the quality of reporting was generally poor. The methods for reporting surgical outcomes for trigeminal neuralgia were not uniform; therefore, the comparability of results and techniques was low. Data should be collected and reported in a standardized way. A protocol for data collection and reporting on the surgical treatment of trigeminal neuralgia has been proposed. Further research is needed to evaluate this tool.

Clinical Protocols↗

Trigeminal neuralgia.

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Analgesics, Non-Narcotic↗