Biomedical subjects

Beverly Wulfeck

Publications and source records attributed to Beverly Wulfeck.

8 recordsLinked to original sources

PubMed2006

Perceptual organization and visual immediate memory in children with specific language impairment.

Children with specific language impairment (LI) have deficits on some nonverbal tasks, but it is not clear if these are related to specific visuospatial deficits or to more general deficits in processing strategies. Children with LI were given two visuospatial tasks that we have shown to be sensitive to strategy use as well as specific processing deficits. In Study 1, children with LI (N=29, ages 6 to 12 years) performed significantly worse than typically developing children (N=26) on the Hierarchical Forms Memory task. In Study 2, children with LI (N=15; ages 9 to 12 years) performed significantly worse than typically developing children (N=40) on the Rey-Osterrieth Complex Figure task. Children with LI were less accurate and tended to use a fairly piecemeal (immature) strategy when copying the figure and were less likely to draw the core rectangle in a more integrated fashion during the immediate memory condition. These results suggest children with LI have subtle deficits on visuospatial tasks that may be more indicative of limitations associated with processing load and planning than of specific visuospatial processing deficits.

Child↗

PubMed2004

How 'generalized' is the 'slowed processing' in SLI? The case of visuospatial attentional orienting.

The study was designed to assess the speed and efficiency of visuospatial attentional orienting and the speed of visual processing and motor response in school-age children diagnosed with specific language impairment (SLI). Fifteen participants with SLI (7-15 years old) and their gender- and age-matched normally developing peers performed two formats of a simple visual discrimination task, one requiring the use of attentional orienting for accurate performance, and the other not requiring shifts of attention. The SLI group was characterized by (a) slower visual processing, and (b) slower motor response, but (c) similar attentional orienting speed, relative to the control group. The results are discussed in relation to the 'generalized slowing hypothesis' in SLI and the neural underpinning of visuospatial attentional orienting and SLI.

Adolescent↗

PubMed2004

Mechanisms of verbal memory impairment in four neurodevelopmental disorders.

Profiles of verbal learning and memory performance were compared for typically developing children and for four developmental disorders characterized by different patterns of language functioning: specific language impairment, early focal brain damage, Williams Syndrome, and Down Syndrome. A list-learning task was used that allowed a detailed examination of the process of verbal learning, recall, and recognition (California Verbal Learning Test--Children's Version). Distinct patterns of performance characterized the four disorders. These patterns were consistent with the language deficits typically seen in the disorders, with the exception of a dissociation seen in Williams Syndrome.

Adolescent↗

PubMed2004

The development of morphosyntactic ability in atypical populations: The acquisition of tag questions in children with early focal lesions and children with specific-language impairment.

We examined the development of some features of morphosyntactic ability, specifically the acquisition of auxiliaries and use of agreement marking, along with sentence processing capacity. We used a conceptually simple task called the Tags Question Task, which is a method for evaluating a number of language processes in the production of a commonly used, familiar linguistic device. We compared the performance of children with early focal lesions (N=21), children with specific-language impairment (N=24), and typically developing children (N=24) matched in age and nonverbal ability; additional analyses involved comparisons of children matched on performance level. The data converge to support a "delayed" development of language behavior in our clinical groups, as overall patterns of performance and age-related changes on individual tag features and tag questions were strikingly similar in all three groups across a number of methods of comparison. Implications for theories of the development of brain-language relationships as they pertain to early focal brain damage, specific-language impairment, and the language acquisition process in typically developing children are discussed.

Adolescent↗

PubMed2004

Productive use of the English past tense in children with focal brain injury and specific language impairment.

In this study, 22 children with early left hemisphere (LHD) or right hemisphere (RHD) focal brain lesions (FL, n=14 LHD, n=8 RHD) were administered an English past tense elicitation test (M=6.5 years). Proportion correct and frequency of over-regularization and zero-marking errors were compared to age-matched samples of children with specific language impairment (SLI, n=27) and with typical language development (TD, n=27). Similar rates of correct production and error patterns were observed for the children with TD and FL; whereas, children with SLI produced more zero-marking errors than either their FL or TD peers. Performance was predicted by vocabulary level (PPVT-R) for children in all groups, and errors did not differ as a function of lesion side (LHD vs. RHD). Findings are discussed in terms of the nature of brain-language relations and how those relationships develop over the course of language learning.

Brain Injuries↗

PubMed2004

Grammaticality sensitivity in children with early focal brain injury and children with specific language impairment.

Grammaticality judgments and processing times associated with violation detection were examined in typically developing children, children with focal brain lesions (FL) acquired early in life, and children with specific language impairment (SLI). Grammatical sensitivity in the FL group, while below typically developing children, was above levels seen in children with SLI. Age effects were noted with developmental changes in sensitivity extending into adolescence. Developmental delays in grammatical processing were particularly pronounced for children with SLI, who showed sensitivity levels below those of younger typically developing children. Sensitivity to agreement violations was also protracted in the SLI group providing further evidence of the vulnerability of morphology, a pattern not unlike that seen in adult aphasics. Findings for the FL group provide compelling evidence of neural and behavioral plasticity in children with early unilateral brain injury. Moreover, results from these children underscore how very different compensatory organization may be compared to profiles seen in adult aphasics who have comparable lesions. In contrast, although it was expected that the SLI children would perform below the typically developing children, the disadvantage seen with respect to the FL group suggests that the underlying pathology responsible for SLI may be more pervasive and less plastic than the focal pathology of children with early brain damage.

Age Factors↗

PubMed2004

"Frog, where are you?" Narratives in children with specific language impairment, early focal brain injury, and Williams syndrome.

In this cross-population study, we use narratives as a context to investigate language development in children from 4 to 12 years of age from three experimental groups: children with early unilateral focal brain damage (FL; N=52); children with specific language impairment (SLI; N=44); children with Williams syndrome (WMS; N=36), and typically developing controls. We compare the developmental trajectories of these groups in the following domains: morphological errors, use of complex syntax, complexity of narrative structure, and types and frequency of evaluative devices. For the children with early unilateral brain damage, there is initial delay. However, by age 10, they are generally within the normal range of performance for all narrative measures. Interestingly, there are few, if any, side specific differences. Children with SLI, who have no frank neurological damage and show no cognitive impairment demonstrate significantly more delay on all morphosyntactic measures than the FL group. Quantitatively, on morphosyntactic measures, the SLI group clusters with those children with WMS who are moderately retarded. Together these data help us to understand the extent and nature of brain plasticity for language development and those aspects of language and discourse that are dissociable.

Brain Injuries↗

PubMed2004

The development of complex sentence interpretation in typically developing children compared with children with specific language impairments or early unilateral focal lesions.

This study compared sentence comprehension skills in typically developing children 5-17 years of age, children with language impairment (LI) and children with focal brain injuries (FL) acquired in the pre/perinatal period. Participants were asked to process sentences 'on-line', choosing the agent in sentences that varied in syntactic complexity (actives, passives, subject clefts and object clefts), and in the presence or absence of a subject-verb agreement contrast. Results revealed that accuracy and processing speeds vary with syntactic complexity in all groups, reflecting the frequency and regularity of sentence types. Developmental changes continued throughout childhood, as children became faster and more accurate at processing more complex sentence structures. Children with LI and children with FL were quite profoundly delayed, displaying profiles similar to, or more impaired than those of younger children, but there was no evidence in the FL group for a disadvantage in left- vs. right-hemisphere-damaged children. Children with LI showed one unique pattern: higher than normal costs (reflected in reaction times) in using converging information from subject-verb agreement, in line with studies suggesting special vulnerabilities in grammatical morphology in this group. Results are discussed in terms of the Competition Model, a theory of language processing designed to account for the statistical changes in performance that are observed during development, and the probabilistic deficits in children with language impairments.

Adolescent↗