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Biomedical subjects

Biagio Guarneri

Publications and source records attributed to Biagio Guarneri.

5 recordsLinked to original sources
PubMed2004

Correlation between endocrinological parameters and acne severity in adult women.

Many studies demonstrate increased androgen levels and high prevalence of polycystic ovaries in women affected by acne. We evaluated the relationship between clinical features, ultrasonographic data on polycystic ovaries and hormonal parameters in 129 women >17 years of age with acne. Serum levels of androgens of ovarian and adrenal origin were measured. Menstrual cycle regularity, hirsutism, body mass index and ultrasonographic evaluation of ovaries were recorded. Raised levels of at least one androgen were evident in a majority of our patients. Only 19% of them had polycystic ovary syndrome. Hirsutism and acne severity correlated negatively with serum sex hormone-binding globulin (SHBG) levels (p<0.05). No correlation between acne severity and hirsutism was found. In post-pubertal women, severity of acne seems to depend on peripheral hyperandrogenism, with a negative relationship between the acne severity and serum SHBG levels. We strongly recommend the evaluation of serum SHBG levels in women with acne in order to select patients who can have a better response to appropriate hormonal regimes.

Acne Vulgaris↗
PubMedDate not supplied

Erythematous-edematous-infiltrative plaque on the face: cutaneous angio-lupoid leishmaniasis.

The present report deals with an unusual clinical presentation of cutaneous leishmaniasis occurring in an atopic subject and discusses the possible pathogenetic mechanisms with particular attention to the role of nitric oxide in the immunological control against intracellular parasites. The altered balance between TH1 and TH2, typical of atopy, with consequent production of IL-4, might contribute to the high susceptibility to opportunistic infections and to the unusual clinical presentation. Moreover the laxity of the tissue and the great vascularization may enhance cutaneous expression of the Leishmania infestation, producing new aspects which add to the difficulty of diagnosis.

Administration, Topical↗
PubMedDate not supplied

Trombiculiasis: clinical contribution.

Neotrombicula autumnalis is an arthropod usually living in the soil, except for the short period of the larval stage when it becomes a real parasite of warm-blooded hosts. We present a case of human trombiculiasis, which is unusual because of the parasite transmission from animals to humans, as in a typical synanthropic dermatosis.

Adult↗