Biomedical subjects

Biao Yu

Publications and source records attributed to Biao Yu.

40 records · Page 3Linked to original sources

PubMed2002

Three new homoisoflavanone glycosides from the bulbs of Ornithogalum caudatum.

Phytochemical examination of Ornithogalum caudatum led to the isolation of three new homoisoflavanone glycosides. Their structures were elucidated, on the basis of the spectroscopic data and chemical evidence and by comparing them with those of known compounds, as (-)-7-O-methyleucomol 5-O-beta-D-glucopyranoside (1), (-)-7-O-methyleucomol 5-O-beta-rutinoside (2), and (-)-7-O-methyleucomol 5-O-beta-neohesperidoside (3), respectively.

Adenocarcinoma, Bronchiolo-Alveolar↗

PubMed2002

Iridoids from the rhizomes and roots of Valeriana jatamansi.

Five new iridoids, 1-homoacevaltrate (1), 1-homoisoacevaltrate (2), 11-homohydroxyldihydrovaltrate (3), 10-acetoxy-1-homovaltrate hydrin (4), and 10-acetoxy-1-acevaltrate hydrin (5), along with 10 known analogues, were isolated from the rhizomes and roots of Valeriana jatamansi. Structural elucidation was based on spectroscopic data interpretation.

China↗

PubMed1999

First Total Synthesis of an Exceptionally Potent Antitumor Saponin, OSW-1.

OSW-1 (1), an acylated disaccharide cholestane saponin from Ornithogalum saudersiae with exceptionally potent antitumor activity, was first synthesized from commercially available dehydroisoandrosterone, L-arabinose, and D-xylose in total 27 steps with the longest linear sequence of 14 steps and in 6% yield.

Journal Article↗

PubMed1997

Total Synthesis of Tricolorin A.

Tricolorin A (1), a structurally amazing resin glycoside with promising bioactivities from Ipomoea tricolor cav. (convolvulaceae), was synthesized in a total of 45 steps, with the longest linear sequence of 20 steps and overall yield of 0.65% from D-mannitol. The AB disaccharide 19-membered lactone 2 was constructured by a regioselective macrolactonization using Corey-Nicolaou protocol. The macrolactone tetrasaccharide 33 was realized either by "one-pot two-step" glycosylation procedure or by a stepwise assembly employing the "armed-disarmed" glycosylation strategy.

Journal Article↗