Biomedical subjects

Bo Ying

Publications and source records attributed to Bo Ying.

10 recordsLinked to original sources

PubMed2006

Involvement of spinal glia in tetanically sciatic stimulation-induced bilateral mechanical allodynia in rats.

The previous study showed involvement of spinal glia in tetanically sciatic stimulation-induced long-term potentiation (LTP) of C-fiber-evoked field potentials in the spinal dorsal horn. In the present study, the electrophysiological recording and paw withdrawal threshold (PWT) to von Frey stimulation were assessed following unilaterally tetanically sciatic stimulation in rats. Tetanic stimuli elicited LTP of both A- and C-fiber-evoked field potentials. After stimulation with the same parameter, bilateral PWTs to mechanical stimuli decreased. Intrathecal administration of fluorocitrate (1 nmol/10 microl), an astrocyte inhibitor, partially inhibited tetanic stimulation-induced reduction of bilateral PWTs. A similar effect also occurred at the contralateral side. And this bilateral inhibition of mechanical threshold lasted 8 days. Similarly, intrathecal administration of d-amino acid oxygenase (50 microg/mul, 10 microl), D-serine inhibitor, partially inhibited tetanic sciatic stimulation-induced reduction of bilateral PWTs for 24 h. The results showed that spinal glia plays an important role in bilaterally mechanical allodynia by tetanic sciatic stimulation of the sciatic nerve.

Animals↗

PubMed2006

[Determination of chlorophenols in drinking water by headspace solid phase microextraction and gas chromatography].

OBJECTIVE: To study the method for determination of chlorophenols in drinking water by headspace solid phase microextraction and gas chromatography. METHODS: Chlorophenols in water samples was extracted using optimized SPME technology, separated by HP-5 chromatigraphic column and the concentration of chlorophenols was determined by electron capture detector (ECD). RESULTS: The detection limit of MCP, DCP, TCP, PCP were 60.0 microg/L, 2.64 microg/L, 0.15 microg/L and 0.84 microg/L. The correlation coefficient(r) were 0.999, 0.997, 0.997, 0.995. When adding standard material of MCP, DCP, TCP, PCP at low, middle, high concentrations, the recovery rates were 95.3% - 107%, 93.6% - 102%, 92.4% - 102%, 91.5% -99.1% and the RSD (n = 6) were 1.0% - 8.1%,1.6% - 6.6%, 2.9% - 8.6%, 2.0% - 8.2%. CONCLUSION: The method was simple, sensitive and without solvent, which was an ideal method for determination of chlorophenols in drinking water.

Chlorophenols↗

PubMed2006

[Rapid detection of toxic substances in water with ToxY-PAM].

A new type of dual-channel PAM fluorometer (ToxY-PAM) was developed for highly sensitive detection of toxic substances in water samples. In conjunction with suspension of unicellular algae as the biotest material, the ToxY-PAM provided a highly rapid and sensitive bioassay test system for the detection of toxic substances in water samples, which could directly or indirectly produce the inhibition of photosynthetic activity in algae. The development process of the detection of toxic substances in water with fluorescence technique, the basic principle and operation of the ToxY-PAM were reviewed in this paper.

Biosensing Techniques↗

PubMed2006

[Determination of trace bromate in drinking water by ion chromatography with suppressed conductivity detection].

Bromate is a common disinfection by-product produced from the ozonation of source water containing bromide. An ion exchange chromatographic method with suppressed conductivity detection for the determination of trace bromate in drinking water was developed. The separation of the bromate in drinking water was achieved on a Metrosep A Supp 5 anion exchange column and a Metrosep A Supp 4/5 Guard column with a carbonate eluent. A new dual suppressed system, an MSM II chemical suppressor combined with a CO2 suppressor, was used to suppress the background conductivity, and to improve the detection limit of bromate. Ion chromatographic experiments were carried out by using a Metrosep A Supp 5 anion exchange column with a suppressed conductivity detector and an eluent of 3.2 mmoL/L Na2CO3-1.0 mmol/L NaHCO3 at a flow rate of 0.65 mL/min. This method had good linearity (r = 0.9999) in the range of 5-100 microg/L and high precision (relative standard deviation (RSD) < 4% ) for three concentration levels of bromate. The average recoveries of the spiked samples including tap water, pure water and mineral water were 96.1%-107%, and the detection limit for bromate was 0.50 microg/L. This method has a simple operation procedure, good separation results, high sensitivity and good repeatability. It can be used as a standard method for the determination of bromate in drinking water.

Bromates↗

PubMed2006

[Determination of total sulfur in coal by ion chromatography].

OBJECTIVE: To develop a method for determination of total sulfur in coal by ion chromatography. METHODS: To pretreat the coal by high-temperature combustion with oxygen-flow in tube furnace, and the sulfur with any from in coal was oxidated and converted into oxid of sulfur, which became sulfate after oxidated by H2O2 absorption solution. The separation of sulfate was achieved on DionexAS12A anion exchange column with a carbonate eluent, and the detection is performed by the suppressed conductivity detector with the injection volume of 50 microl. The total sulfur in coals were obtained from the determined results. RESULTS: The method had been compared with the National Standard Method "High-Temperature Combustion--Neutralization Method for Determination of Total Sulfur in Coal (GB/T214-1996)", and the RSD of the method was less than 2% . This method had good relativity of the linearity (r = 0.9998) at the range of 0 to approximately 15 microg/ml for sulfate. Two kinds of national certified reference materials (GBW11104c and GBWl1110d) were determined, and the RSD were 1.92% and 0.47% respectively. CONCLUSION: Ion chromatography for determination of total sulfur in coal has simple operation, high accuracy, and fast analysis, and can be applied in determination of total sulfur in coal.

Air Pollution↗

PubMed2005

Geographical, spatial, and temporal distributions of multiple indoor air pollutants in four Chinese provinces.

Exposure to indoor air pollution from household energy use depends on fuel, stove, housing characteristics, and stove use behavior. We monitored three important indoor air pollutants-respirable particles (RPM), carbon monoxide (CO), and sulfur dioxide (SO2)-for a total of 457 household-days in four poor provinces in China (Gansu, 129 household-days; Guizhou, 127 household-days; Inner Mongolia, 65 household-days; and Shaanxi, 136 household-days), in two time intervals during the heating season to investigate spatial and temporal patterns of pollution. The two provinces where biomass is the primary fuel (Inner Mongolia and Gansu) had the highest RPM concentrations (719 microg/m3 in the single cooking/living/bedroom in Inner Mongolia in December and 351-661 microg/m3 in different rooms and months in Gansu); lower RPM concentration were observed in the primarily coal-burning provinces of Guizhou and Shaanxi (202-352 microg/m3 and 187-361 microg/m3 in different rooms and months in Guizhou and Shaanxi, respectively). Inner Mongolia and Gansu also had higher CO concentrations (7.4 ppm in the single cooking/living/bedroom in Inner Mongolia in December and 4.8-11.3 ppm in different rooms and months in Gansu). Among the two primarily coal-burning provinces, Guizhou had lower concentrations of CO than Shaanxi (1.2-1.8 ppm in Guizhou vs 2.0-13.3 ppm in different rooms and months in Shaanxi). In the two coal-burning provinces, SO2 concentrations were substantially higher in Shaanxi than in Guizhou. Relative concentrations in different rooms and provinces indicate that in the northern provinces heating is an important source of exposure to indoor pollutants from energy use. Day-to-day variability of concentrations within individual households, although substantial, was smaller than variation across households. The implications of the findings for designing environmental health interventions in each province are discussed.

Air Pollutants↗

PubMed2005

Patterns of household concentrations of multiple indoor air pollutants in China.

Most previous studies on indoor air pollution from household use of solid fuels have used either indirect proxies for human exposure or measurements of individual pollutants at a single point, as indicators of (exposure to) the mixture of pollutants in solid fuel smoke. A heterogeneous relationship among pollutant-location pairs should be expected because specific fuel-stove technology and combustion and dispersion conditions such as temperature, moisture, and air flow are likely to affect the emissions and dispersion of the various pollutants differently. We report on a study for monitoring multiple pollutants--including respirable particles (RPM), carbon monoxide, sulfur dioxide, fluoride, and arsenic--at four points inside homes that used coal and/or biomass fuels in Guizhou and Shaanxi provinces of China. All pollutants exhibited large variability in emissions and spatial dispersion within and between provinces and were generally poorly correlated. RPM, followed by SO2, was generally higher than common health-based guidelines/standards and provided sufficient resolution for assessing variations within and between households in both provinces. Indoor heating played an important role in the level and spatial patterns of pollution inside homes, possibly to an extent more important than cooking. The findings indicate the need for monitoring of RPM and selected other pollutants in longer-term health studies, with focus on both cooking and living/sleeping areas.

Air Pollutants↗

PubMed2003

[Relations between trace elements in drinking water and elderly residents' cognitive function].

The relationship between trace element levels in drinking water and cognitive function was studied for elderly residents in rural areas in China. Cognitive function was measured by a Chinese translation of the Community Screening Interview for Dementia (CSI "D"). The trace elements fluoride, calcium, selenium, aluminum, iron, zinc, cadmium, lead and arsenic contents of drinking water were determined using Chinese. National Standard Methods. A mixed effects model was used to evaluate the effect of each of the elements on cognitive function while adjusting for age, sex, and education level. Several of the elements examined had a significant effect on cognitive function when they were examined in a univariate context. However, after adjusting for other elements many of these results were not significant. There was a significant quadratic effect for calcium and a significant zinc-cadmium interaction. Cognitive function increased with calcium level to a certain point, and then decreased as calcium continued to increase. Zinc showed a positive relationship with cognitive function at low cadmium levels, but a negative relationship at high cadmium levels.

Aged↗

PubMed2002

[Study on the regeneration methods of the synthetic hydroxyapatite as a material for defluoridation of drinking water].

The regeneration efficiencies of the synthetic hydroxyapatite saturated by fluoride using either sodium hydroxide method or surface coating method are studied and compared. Both static and dynamic conditions for surface coating regeneration method are also tested. The results showed that the regeneration efficiency of the synthetic hydroxyapatite saturated by fluoride treated by surface coating method is 46%-64%, more than two times of that of it treated by the traditional sodium hydroxide regeneration method.

Fluoridation↗

PubMed2002

[Manufacture of hydroxyapatite as a defluoridator and the mechanism of defluoridation for drinking water].

Hydroxyapatite as a defluoridator for drinking water is characterized by a large capacity of defluoridation, and easy and simple operation in application. The quality of drinking water is not changed, the sorbent is easy to be regenerated, and the second pollution does not occur after the treatment of drinking water with the sorbent. Hydroxyapatite method has advantage over the methods such as actived alumina, bone char and electrodialysis commonly used in defluorination of drinking water. It is for this reason that the components, structural feature, synthesis and application of hydroxyapatite and its mechanism of defluoridation are summarized in this paper.

Durapatite↗