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Bogdan Obrzut

Publications and source records attributed to Bogdan Obrzut.

10 recordsLinked to original sources
PubMed2006

[Discrepancies between clinical and surgical--pathologic staging of cervical carcinoma].

OBJECTIVES: Cervical cancer is the only gynecological tumor staged clinically. The aim of this study was comparison of clinical staging to surgical specimen evaluation in cervical cancer patients. DESIGN: Clinical staging of cervical cancer was compared to histopathological outcome in prospective study. MATERIALS AND METHODS: One hundred patients with cervical cancer treated with radical hysterectomy combined with pelvic lymphadenectomy were included in the study. RESULTS: Discrepancies between clinical and surgico-pathological staging occurred in 62% of cases. The tendency towards overdiagnosis was found to be increasing with local advancement of neoplasm. CONCLUSIONS: Accuracy of preliminary cervical cancer staging needs further improvement.

Adult↗
PubMed2006

Cycle dependent RCAS1 expression with respect to the immune cells presence and activity.

INTRODUCTION: The number of cytotoxic immune cells grows in the endometrium during the secretory cycle phase. RCAS1 is a protein inhibiting the activated immune cytotoxic cells. The expression of RCAS1 has been confirmed in endometrium. The aim of the present study was to evaluate the RCAS1 expression alterations with respect to the menstrual cycle changes and the number and activity of cytotoxic immune cells. MATERIAL AND METHODS: RCAS1, CD25, CD69, CD56, CD16, CD68 antigens expression was assessed by immunohistochemistry in endometrial tissue samples which were obtained from 33 patients. Tissue samples were classified according to the menstrual cycle phases, with division of the cycle into three phases: proliferative (8 cases), periovulatory (10 cases), and secretory (15 cases) ones. RESULTS: A significantly higher RCAS1 expression was observed in the periovulatory and the secretory menstrual cycle phases than in the proliferative phase. The changes in RCAS1 expression were combined with significant differences in the number of immune cells and their activity. The highest level of CD69 antigen expression was observed during the periovulatory cycle phase, while the highest level of CD25 antigen expression was observed during proliferative phase, the number of CD56 positive cells was at the highest level during the secretory cycle phase. No significant differences in the number of macrophages and CD16 antigen expression were observed with respect to the menstrual cycle phases. CONCLUSION: RCAS1 endometrial expression may favor the coexistence of active lymphocytes and endometrial cells.

Adult↗
PubMed2005

Liver dysfunction in severe ovarian hyperstimulation syndrome.

We report the case of a 32-year-old woman suffering from severe liver dysfunction in the course of ovarian hyperstimulation syndrome (OHSS). Complications occurred after successful fertilization subsequent to ovarian stimulation with human menopausal gonadotropin followed by ovulation induction with human chorionic gonadotropin. Because of nausea, vomiting, abdominal distention and enlarged ovaries on an ultrasound examination, she was admitted on the diagnosis of OHSS. During the course of hospitalization severe hepatic injury developed. An increase of more than 100-fold in blood aminotransferase activity was observed. Applied treatment resulted in gradual reduction of ovarian size and resolution of ascites, as well as pleural and pericardial effusions. The patient was discharged from hospital after 46 days. Follow-up examinations at the 13th and 32nd weeks of gestation did not reveal any abnormalities. Pregnancy developed without complications and the woman went into spontaneous labor, giving birth to a viable child at 38 weeks' gestation. Taking into account the above case and previously published reports, the issue of liver dysfunction may have a great impact on the understanding both the pathology and the treatment of OHSS.

Adult↗
PubMed2005

[Modified detachable deschamps ligature carrier (MDDLC) in sacrospinous ligament fixation (SSLF)].

OBJECTIVES: The study presents modified detachable Deschamps ligature carrier (MDDLC), which applied in sacrospinous ligament fixation (SSLF) procedure allows for suture placement through the sacrospinous ligament in a limited pararectal space. MATERIALS AND METHODS: Prototype of new surgical instrument has been applied in paravaginal procedures suspending vaginal vault to the sacrospinous ligament among other reconstructive procedures performed on nine patients with genital prolapse. RESULTS: No complications have been noticed with the use of new device. CONCLUSIONS: MDDLC, designed and accomplished by authors, is simple in its construction and easy in application.

Equipment Design↗
PubMed2004

[Preliminary evaluation of synthetic materials used in gynecologic operations through the vagina].

OBJECTIVES: The aim of the study was to evaluate the outcomes of meshes' use in gynecological vaginal operations. DESIGN: A prospective analysis of early postoperative results and complications. MATERIALS AND METHODS: All patients were operated on in Gynecological Department of District Hospital in Rzeszow. The investigated group consisted of 37 women suffering from pelvic organ prolapse. The degree of prolapse was evaluated with modified Baden Walker scale before procedure and three months after operation. Operations with use of synthetic materials (anterior and posterior colporraphy) were performed parallel with other gynecological procedures. The results of operations were compared to control group matched according to the age and parity. The control group consisted of patients operated on because of genital organs disorders excluding genital prolapse. RESULTS: The reduction of genital prolapse degree was found in all patients. In 3/4 of them it was degree 0 in Baden-Walker modified scale. CONCLUSIONS: The synthetic materials may be used in gynecological vaginal surgery together with conventional procedures. The advantages of operations with meshes' use are high efficacy and small number of complications.

Adult↗
PubMed2004

[Guillain-Barre syndrome during CMV infection complicating twin pregnancy--a case report].

A rare case of Guillain-Barre syndrome in the course of an acute CMV infection during twin pregnancy was reported. A clinical picture, diagnostic procedure and therapeutic management of CMV infection and its complications were presented. The reported case indicates that CMV infections should be taken into account in differential diagnosis in pregnant women with unclear neurological symptoms.

Adult↗
PubMed2003

[Laparoscopic-vaginal radical hysterectomy in surgical treatment of cervical cancer].

Radical vaginal hysterectomy has been performed in surgical treatment of cervical cancer for over one hundred years. After the term of decrease of popularity of this operation, nowadays we can observe gradual come back to the idea of radical vaginal hysterectomy. Possibility of association of advanced laparoscopic techniques/lymphadenectomy/with vaginal operation have changed the approach to the surgical treatment of cervical cancer. The aim of the study is to present the method of laparoscopic-vaginal radical hysterectomy based on Schauta-Amreich technique. The 51 year old women was admitted to the hospital and cervical cancer FIGO stage IIA was diagnosed according to clinical and histopathological examination. We performed laparoscopic-vaginal radical hysterectomy in general anaesthesia. First after cutting of ligamentum teres uteri and infundibulo-pelvicum, laparoscopic pelvic lymphadenectomy was done. Subsequently vaginal stage of operation was performed. Then we did laparoscopy and controlled operation field again. Combining Schauta operation with laparoscopy allows us to estimate lymph nodes as well as make vaginal phase of operation easier because of mobilization of uterus. We consider that laparoscopic-vaginal radical hysterectomy could be a valuable element in broadening the spectrum of many kinds of operations used in treatment of cervical cancer.

Carcinoma, Squamous Cell↗
PubMed2002

[Skinning vulvectomy in the treatment of carcinoma in situ of the vulva--case report].

There has been a case presented of multifoci preinvasive cancer in a twenty three years old female. In the case an operation has been performed involving a superficial excision of the changing vulvar skin. On the basis of meta-analysis we compared the efficiency of the performed surgical method and other destructive techniques used in the intraepithelial vulvar neoplasm treatment.

Adult↗
PubMedDate not supplied

The PCR assessed prevalence of Chlamydia trachomatis in aborted tissues.

BACKGROUND: Infections caused by Chlamydia trachomatis (ChT) are the most prevalent sexually transmitted bacterial infections worldwide. ChT is a cause of cervicitis, endometritis, salpingitis, tubal infertility and ectopic pregnancy. Perinatal infections with ChT have been associated with premature rupture of membranes, stillbirth, preterm delivery, and in newborns with conjunctivitis and pneumonia. There are controversial data referring to the association between colonisation by ChT and the risk of spontaneous abortion. Only few studies investigated the prevalence of ChT antigens in aborted tissues. AIM: To determine the prevalence of ChT in patients with spontaneous pregnancy loss using Polymerase Chain Reaction (PCR). MATERIALS AND METHOD: We completed prospective analysis of 50 patients after spontaneous abortions. The prevalence of ChT infections was assessed by PCR performed in samples taken during curettage following miscarriage. RESULTS: ChT was present in 16 (32%) of samples. Other pathogens of the lower genital tract were found in cultures from 11 patients. CONCLUSIONS: The prevalence of ChT infections in early abortions in this study was found to be surprisingly high. It implies the importance of screening of women planning pregnancy and pregnant women for this disease.

Aborted Fetus↗