The National Occupational Research Agenda--the second decade of NORA.
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Biomedical subjects
Publications and source records attributed to Bonnie Rogers.
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OBJECTIVE: To assess whether exposure to standing, lifting, night work, or long work hours during 3 periods of pregnancy are associated with an increased risk of preterm or small-for-gestational-age birth. METHODS: The Pregnancy, Infection and Nutrition study is a prospective cohort with a nested case-control component that was conducted through clinic and hospital settings in Central North Carolina. A total of 1,908 women pregnant with a singleton gestation were recruited during prenatal visits from January 1995 through April 2000 and provided information during telephone and face-to-face interviews about physical exertion for the 2 longest-held jobs during pregnancy. RESULTS: No significant elevations in preterm delivery were observed among women who lifted repeatedly or stood at least 30 hours per week, with no changes in risk estimates over the course of pregnancy. A 50% elevation in the risk of preterm delivery (relative risk 1.5, 95% confidence interval 1.0-2.0; first trimester) was observed among women who reported working at night (10:00 PM to 7:00 AM), whereas a 40% reduction in risk was observed among women working at least 46 hours per week (relative risk 0.6, 95% confidence interval 0.4-0.9; first trimester), regardless of period of exposure. No elevations in small-for-gestational-age birth were observed among women exposed to any of the 4 types of occupational exertion. CONCLUSION: Physically demanding work does not seem to be associated with adverse pregnancy outcomes, whereas working at night during pregnancy may increase the risk of preterm delivery. Studies to examine the effect of shift work on uterine activity would help to clarify the possibility of a causal effect on preterm birth.
Workers as study participants are a vulnerable population and additional considerations for their protection in research are needed. Issues related to invasion of privacy and coercion to participate in research studies must be carefully weighed and closely monitored. Worker autonomy must be fostered with respect to assuring that informed consent is given, meaning the information transferred is understood. Research will add to the body of knowledge and advance nursing practice, but one must always remember that risks and benefits must be balanced to achieve appropriate end results.
Pediatric medical and nursing education currently lacks the environmental health content necessary to appropriately prepare pediatric health care professionals to prevent, recognize, manage, and treat environmental-exposure-related disease. Leading health institutions have recognized the need for improvements in health professionals' environmental health education. Parents are seeking answers about the impact of environmental toxicants on their children. Given the biologic, psychological, and social differences between children and adults, there is a need for environmental health education specific to children. The National Environmental Education and Training Foundation, in partnership with the Children's Environmental Health Network, created two working groups, one with expertise in medical education and one with expertise in nursing education. The working groups reviewed the transition from undergraduate student to professional to assess where in those processes pediatric environmental health could be emphasized. The medical education working group recommended increasing education about children's environmental health in the medical school curricula, in residency training, and in continuing medical education. The group also recommended the expansion of fellowship training in children's environmental health. Similarly, the nursing working group recommended increasing children's environmental health content at the undergraduate, graduate, and continuing nursing education levels. Working groups also identified the key medical and nursing organizations that would be important in leveraging these changes. A concerted effort to prioritize pediatric environmental health by governmental organizations and foundations is essential in providing the resources and expertise to set policy and provide the tools for teaching pediatric environmental health to health care providers.
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In most studies, the investigator reaches out to locate potential research subjects using direct strategies such as targeted radio advertising, recruitment posters, and newspaper advertisements. However, other studies may depend on indirect methods of locating potential subjects and work through intermediary contacts in clinics and hospital outpatient departments. Some agency personnel may not have had prior experience with clinical research protocols and may be unfamiliar with screening potential subjects; these personnel are likely to be employed in agencies unaffiliated with academic health sciences centers. In cases in which agency staff members are new to clinical research, special attention is required to keep agency personnel updated about the status of the research and subject recruitment efforts. This article provides an overview of practical tips designed to engage and sustain the interest of novice research agencies in subject recruitment. The article concludes with a case overview of recruitment issues that occurred during a clinical trial addressing occupational low back pain.
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